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Prednisone (Prednisone) - Side Effects and Adverse Reactions

 
 



ADVERSE REACTIONS

Fluid and Electrolyte Disturbances:

  •  Sodium retention.
  •  Fluid retention.
  •  Congestive heart failure in susceptible patients.
  •  Potassium loss.
  •  Hypokalemic alkalosis.
  •  Hypertension.

Musculoskeletal:

  •  Muscle weakness.
  •  Steroid myopathy.
  •  Loss of muscle mass.
  •  Osteoporosis.
  •  Vertebral compression fractures.
  •  Aseptic necrosis of femoral and humeral heads.
  •  Pathologic fracture of long bones.

Gastrointestinal:

  •  Peptic ulcer with possible perforation and hemorrhage.
  •  Pancreatitis.
  •  Abdominal distention.
  •  Ulcerative esophagitis.

Dermatologic:

  •  Impaired wound healing.
  •  Thin fragile skin.
  •  Petechiae and ecchymoses.
  •  Facial erythema.
  •  Increased sweating.
  •  May suppress reactions to skin tests.

Neurological:

  •  Convulsions.
  •  Increased intracranial pressure with papilledema (pseudo-tumor cerebri) usually after treatment.
  •  Vertigo.
  •  Headache.

Endocrine:

  •  Menstrual irregularities.
  •  Development of cushingoid state.
  •  Suppression of growth in children.
  •  Secondary adrenocortical and pituitary unresponsiveness, particularly in times of stress, as in trauma, surgery or illness.
  •  Decreased carbohydrate tolerance.
  •  Manifestations of latent diabetes mellitus.
  •  Increased requirements for insulin or oral hypoglycemic agents in diabetics.

Ophthalmic:

  •  Posterior subcapsular cataracts.
  •  Increased intraocular pressure.
  •  Glaucoma.
  •  Exophthalmos.

Metabolic:

  •  Negative nitrogen balance due to protein catabolism.


REPORTS OF SUSPECTED PREDNISONE SIDE EFFECTS / ADVERSE REACTIONS

Below is a sample of reports where side effects / adverse reactions may be related to Prednisone. The information is not vetted and should not be considered as verified clinical evidence.

Possible Prednisone side effects / adverse reactions in 82 year old female

Reported by a health professional (non-physician/pharmacist) from Turkey on 2011-10-03

Patient: 82 year old female

Reactions: Febrile Neutropenia

Adverse event resulted in: death

Suspect drug(s):
Cyclophosphamide
    Dosage: cycle 2

Rituximab

Doxorubicin Hydrochloride
    Dosage: cycle 1

Vincristine
    Indication: non-Hodgkin's Lymphoma

Rituximab
    Indication: non-Hodgkin's Lymphoma

Prednisone
    Dosage: cycle 2
    Indication: non-Hodgkin's Lymphoma

Doxorubicin Hydrochloride
    Dosage: cycle 1

Doxorubicin Hydrochloride
    Dosage: cycle 2

Cyclophosphamide
    Indication: non-Hodgkin's Lymphoma

Vincristine
    Dosage: cycle 2

Prednisone

Doxorubicin Hydrochloride
    Dosage: cycle 2

Doxorubicin Hydrochloride
    Dosage: cycle 2

Doxorubicin Hydrochloride
    Dosage: cycle 1
    Indication: non-Hodgkin's Lymphoma



Possible Prednisone side effects / adverse reactions in 80 year old male

Reported by a physician from Italy on 2011-10-03

Patient: 80 year old male

Reactions: Transient Ischaemic Attack

Adverse event resulted in: hospitalization

Suspect drug(s):
Prednisone
    Administration route: Oral
    Indication: Prostate Cancer
    Start date: 2011-06-01
    End date: 2011-06-01

Docetaxel
    Indication: Prostate Cancer
    Start date: 2011-06-01
    End date: 2011-06-01

Lenalidomide
    Administration route: Oral
    Indication: Prostate Cancer
    Start date: 2011-06-01
    End date: 2011-06-14

Prednisone
    Administration route: Oral
    Start date: 2011-08-05
    End date: 2011-08-24

Lenalidomide
    Administration route: Oral
    Start date: 2011-08-05
    End date: 2011-08-18

Docetaxel
    Start date: 2011-08-05
    End date: 2011-08-05

Other drugs received by patient: Lansoprazole; Phenobarbital TAB; Filgrastim; Furosemide; Ticlopidine HCL



Possible Prednisone side effects / adverse reactions in 86 year old male

Reported by a physician from Taiwan, Province of China on 2011-10-04

Patient: 86 year old male weighing 65.8 kg (144.8 pounds)

Reactions: Pyrexia

Adverse event resulted in: death, hospitalization

Suspect drug(s):
Prednisone
    Administration route: Oral
    Indication: Prostate Cancer Metastatic

Cabazitaxel
    Indication: Prostate Cancer Metastatic
    Start date: 2011-07-25
    End date: 2011-07-25

Cabazitaxel
    Start date: 2011-09-19
    End date: 2011-09-19



See index of all Prednisone side effect reports >>

Drug label data at the top of this Page last updated: 2008-07-15

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