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Prednisone (Prednisone) - Drug Interactions, Contraindications, Overdosage, etc



Drug Interactions

Amphotericin B Injection and Potassium-Depleting Agents

When corticosteroids are administered concomitantly with potassium-depleting agents (e.g.,), patients should be observed closely for development of hypokalemia. In addition, there have been cases reported in which concomitant use of amphotericin B and hydrocortisone was followed by cardiac enlargement and congestive heart failure. amphotericin B, diuretics


Prednisone tablets and oral solutions are contraindicated in systemic fungal infections and known hypersensitivity to components.


  1. Fekety R. Infections associated with corticosteroids and immunosuppressive therapy. In: Gorbach SL, Bartlett JG, Blacklow NR, eds.. 1. Infectious Diseases
  2. Philadelphia: WBSaunders Company 1992:1050-1.  
  3. Stuck AE, Minder CE, Frey FJ. Risk of infectious complications in patients taking glucocorticoids. 1989:11(6):954-63. 2. Rev Infect Dis

Roxane Laboratories, Inc.

Columbus, Ohio 43216

10002425/05 Revised November 2012

© RLI, 2012

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