Precedex (Dexmedetomidine Hydrochloride) - Summary

PRECEDEX SUMMARY

Precedex^®
Dexmedetomidine
Hydrochloride
Injection

PPrecedex^® (dexmedetomidine hydrochloride injection) is a sterile, nonpyrogenic solution suitable for intravenous infusion following dilution. Dexmedetomidine hydrochloride is the S-enantiomer of medetomidine and is chemically described as (+)-4-(S)-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole monohydrochloride.

Precedex^® is indicated for sedation of initially intubated and mechanically ventilated patients during treatment in an intensive care setting. Precedex^® should be administered by continuous infusion not to exceed 24 hours.

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PRECEDEX NEWS HIGHLIGHTS

Published Studies Related to Precedex (Dexmedetomidine)

Dexmedetomidine weakens dynamic cerebral autoregulation as assessed by transfer function analysis and the thigh cuff method. [2008.10]

The effect of dexmedetomidine on perioperative hemodynamics in patients undergoing craniotomy. [2008.10]

Motor and somatosensory evoked potentials are well maintained in patients given dexmedetomidine during spine surgery. [2008.09]

Effect of intra-articular dexmedetomidine on postoperative analgesia after arthroscopic knee surgery. [2008.09]

[Postoperative management of carotid endarterectomy with dexmedetomidine--a comparison with propofol] [2008.06]

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Clinical Trials Related to Precedex (Dexmedetomidine)

Awake Intubation - Precedex Used for Sedation During Elective Awake Fiberoptic Intubation [Active, not recruiting]

Dexmedetomidine for the Control of Post-Operative Pain in Thoracotomy Patients [Recruiting]

Dexmedetomidine for Immediate Perioperative Analgesia in Pediatric Patients Undergoing Tonsillectomy [Recruiting]

Dexmedetomidine for Peri-Operative Sedation and Analgesia in Children Undergoing Bilateral Myringotomy With Tube Placement (BMT) [Recruiting]

Susceptibility of Motor-Evoked Potentials to Varying Targeted Blood Levels of Dexmedetomidine [Recruiting]

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