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Ponstel (Mefenamic Acid) - Summary

 
 



PONSTEL SUMMARY

Ponstel® (mefenamic acid) is a member of the fenamate group of nonsteroidal anti-inflammatory drugs (NSAIDs). Each blue-banded, ivory capsule contains 250 mg of mefenamic acid for oral administration.

Carefully consider the potential benefits and risks of PONSTEL and other treatment options before deciding to use PONSTEL. Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals (see WARNINGS).

PONSTEL is indicated:

  • For relief of mild to moderate pain in patients ≥14 years of age, when therapy will not exceed one week (7 days).
  • For treatment of primary dysmenorrhea.



See all Ponstel indications & dosage >>

NEWS HIGHLIGHTS

Published Studies Related to Ponstel (Mefenamic Acid)

Comparison of the effects of Matricaria chamomila (Chamomile) extract and mefenamic acid on the intensity of premenstrual syndrome. [2014]
The study aimed to compare the effects of Chamomile Extract and Mefenamic acid (MA) on the intensity of Premenstrual syndrome (PMS) symptoms. This study was a clinical randomized double blind trial, carried out with 90 students living in the dorms of Iran...

Efficacy of mefenamic acid and hyoscine for pain relief during saline infusion sonohysterography in infertile women: a double blind randomized controlled trial. [2011.04]
OBJECTIVES: To evaluate the efficacy and level of satisfaction from mefenamic acid and hyoscine when used for pain relief during saline infusion sonohysterography... CONCLUSION: There is no benefit in using mefenamic acid and hyoscine in the prevention of pain occurring from SIS. Copyright (c) 2010 Elsevier Ireland Ltd. All rights reserved.

Single dose oral mefenamic acid for acute postoperative pain in adults. [2011]
CONCLUSIONS: Oral mefenamic acid 500 mg was effective at treating

Comparison of efficacy of oral drotaverine plus mefenamic acid with paracervical block and with intravenous sedation for pain relief during hysteroscopy and endometrial biopsy. [2009.06]
BACKGROUND: Office hysteroscopy with endometrial biopsy is usually the first investigation for abnormal uterine bleeding and other uterine diseases. AIMS: To evaluate the effect of oral drotaverine with mefenamic acid on pain perception during hysteroscopy and endometrial biopsy and to compare it with that of paracervical block using 1% lignocaine and with that of intravenous sedation using diazepam with pentazocine. SETTINGS AND DESIGN: Outpatient gynecological department and open randomized trial... CONCLUSIONS: Oral drotaverine with mefenamic acid is effective in women undergoing hysteroscopy and endometrial biopsy.

Comparison of the effectiveness of fennel and mefenamic acid on pain intensity in dysmenorrhoea. [2006.05]
A study in Kerman, Islamic Republic of Iran in 2002 compared the effectiveness of fennel and mefenamic acid on pain relief in primary dysmenorrhoea. Two groups of high-school girls (mean age 13 years) suffering dysmenorrhoea were randomized to receive fennel extract (n = 55) or mefenamic acid (n = 55) for 2 months...

more studies >>

Clinical Trials Related to Ponstel (Mefenamic Acid)

Efficacy of Mefenamic Acid and Hyoscine for Pain Relief During Saline Infusion Sonohysterography in Infertile Women [Active, not recruiting]
The infertility patients who are performed saline infusion sonohysterography (SIS) for studying the pathology inside the uterine cavity has pain. From pilot study the pain score is 6. 80. It will have more benefits if we can manage this procedure with less or no pain. Many studies have tried to decrease pain such as types of catheter, intrauterine lidocaine infusion. Some have real effects but no study with oral Mefenamic acid or Hyoscine before the procedure. The drugs are safe and easy to administration and chief.

Efficacy and Safety Study of Meloxicam Versus Mefenamic Acid in Patients With Dysmenorrhea [Completed]
To access the efficacy and safety of Meloxicam 7. 5 mg and 15 mg once daily compared with Mefenamic acid 500 mg t. i.d. over a treatment period of 3-5 days, during an observation period of 3 menstrual cycles, for the symptomatic relief of primary dysmenorrhea

The Efficacy of Ayurved Siriraj Prasaplai for Treatment Primary Dysmenorrhea [Completed]
Ayurved Siriraj Prasaplai is a Thai traditional herbal drug for pain treatment. Mostly it was used for antipain during menstruation or dysmenorrhea. This drug has been described by alternative medical doctor for treatment of primary dysmenorrhea for more than 10 years and showed clinical satisfied response. From review about this agent, it does not have clinical trial to prove its efficacy. So the author produce this research to study in efficacy of Ayurved Siriraj Prasaplai.

Management of Initial Bleeding/Spotting Associated With the Levonorgestrel-releasing Intrauterine System (MIRENA) [Completed]
The purpose of the study is to investigate if the study drugs (tranexamic acid or mefenamic acid) can control irregular bleeding during the first 3 months of using Mirena. The study drugs tested are tested against placebo ("dummy medication not containing any active drug"). Treatment period is followed by a one-month period when study drugs are not taken but Mirena use is continued.

DLBS1442 for The Treatment of Pain in Patients Suspected Endometriosis [Not yet recruiting]
This is a 3-arm, prospective, randomized, double-blind, and controlled study of DLBS1442 for the treatment of pain in patients suspected endometriosis. It is hypothesized that the reduction of the composite-pain intensity (as measured by VAS) from baseline to the end of study (week 8th) resulting from administration of DLBS1442, regardless of the dosage regimen, is significantly greater than that of Control. In addition, the administration of DLBS1442 at higher dose also results in significantly greater reduction than that of DLBS1442 at lower dose and of Control.

more trials >>


PATIENT REVIEWS / RATINGS / COMMENTS

Based on a total of 3 ratings/reviews, Ponstel has an overall score of 9. The effectiveness score is 9.33 and the side effect score is 10. The scores are on ten point scale: 10 - best, 1 - worst.
 

Ponstel review by 25 year old female patient

  Rating
Overall rating:  
Effectiveness:   Highly Effective
Side effects:   No Side Effects
  
Treatment Info
Condition / reason:   menstrual cramps
Dosage & duration:   250 mg. taken every 8-12 hours for the period of 3-4 days
Other conditions:   none
Other drugs taken:   none
  
Reported Results
Benefits:   I was used to having cramps so badly that they would leave me balled up in bed for at least 2 days. The Ponstel doesn't take the pain away completely, but takes the edge off so much that normal activities were possible. Definitely a miracle medication!!
Side effects:   Heavier bleeding and clotting than normal.
Comments:   I took 2 pills at the onset of my menstrual cramps and then every 8-12 hours took 1 pill as needed for about 3-4 days until cramps were over. If cramps are bad, make sure to take every 8 hours on the dot because the medication stops working suddenly and unfortunately takes about an hour to an hour and a half to kick back in.. if cramps are only moderate, taking every 12 hours is okay.

 

Ponstel review by 50 year old female patient

  Rating
Overall rating:  
Effectiveness:   Considerably Effective
Side effects:   No Side Effects
  
Treatment Info
Condition / reason:   migraine
Dosage & duration:   1 to two tablets at first onset of pain taken once a month for the period of 3 years
Other conditions:   none
Other drugs taken:   none
  
Reported Results
Benefits:   Although it did not completely rid me of my migraine it helped to dull the pain. I was actually able to go to work with a migraine instead to taking a day off to just lie still.
Side effects:   no side effects.
Comments:   At the first symptoms of a migraine I wojld pop a copule of tablets. For severe migraines I would repeat the dosage about 8 hours later. However, over time I found the medication to be less effective and ultimately stopped taking it. It seems as though my body became immune to it's effectiveness.

 

Ponstel review by 50 year old female patient

  Rating
Overall rating:  
Effectiveness:   Considerably Effective
Side effects:   No Side Effects
  
Treatment Info
Condition / reason:   migraine
Dosage & duration:   1 to two tablets at first onset of pain taken once a month for the period of 3 years
Other conditions:   none
Other drugs taken:   none
  
Reported Results
Benefits:   Although it did not completely rid me of my migraine it helped to dull the pain. I was actually able to go to work with a migraine instead to taking a day off to just lie still.
Side effects:   no side effects.
Comments:   At the first symptoms of a migraine I wojld pop a copule of tablets. For severe migraines I would repeat the dosage about 8 hours later. However, over time I found the medication to be less effective and ultimately stopped taking it. It seems as though my body became immune to it's effectiveness.

See all Ponstel reviews / ratings >>

Page last updated: 2014-12-01

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