News related to Plenaxis (Abarelix) and/or conditions it is approved for
Prostate Cancer Promotes The Growth Of New Nerves And The Branching Axons That Carry Their Messages
Source: Health News from Medical News Today [2008.12.01]
Prostate cancer - and perhaps other cancers - promotes the growth of new nerves and the branching axons that carry their messages, a finding associated with more aggressive tumors, said researchers from Baylor College of Medicine in the first report of the phenomenon that appears today in the journal Clinical Cancer Research.
Dynamic Change In Phosphorylated PDGFR In Peripheral Blood Leukocytes After Docetaxel Therapy Predicts Overall Survival In Prostate Cancer
Source: Cancer / Oncology News From Medical News Today [2008.12.01]
UroToday.com - Accurate molecular markers for targeted therapy that correlate with traditional clinical outcomes are not common. An online article from a distinguished group of researchers demonstrates how useful this approach may be. As background, the combination of platelet-derived growth factor receptor (PDGFR) inhibition and taxane chemotherapy for CaP patients with bone metastasis has not demonstrated improved progression-free survival or overall survival benefit.
Plumbagin, A Medicinal Plant-Derived Naphthoquinone, Is A Novel Inhibitor Of The Growth And Invasion Of Hormone-Refractory Prostate Cancer
Source: Cancer / Oncology News From Medical News Today [2008.12.01]
UroToday.com - Dr. Moammir Aziz and colleagues from the University of Wisconsin reported in the November 1, 2008 issue of Cancer Research that plumbagin, a medicinal plant derived naphthoquinone, inhibits castration-resistant prostate cancer (CaP) growth and invasion. Plumbagin was isolated from the roots of plumbago zeylannica L. (Chitrak), which has been used in Indian medicine for thousands of years.
Prostate cancer radiotherapy safe for HIV patients (Reuters)
Source: Y! Health Cancer & Chemotherapy News [2008.12.01]
Reuters - The results of small study suggest that radiotherapy can be safely used to treat prostate cancer in HIV-infected men. Treatment appears to have no long-term effect on CD4+ cell count or viral load.
Age And Grade Trends In Prostate Cancer (1974-2003): A Surveillance, Epidemiology, And End Results Registry Analysis
Source: Cancer / Oncology News From Medical News Today [2008.11.30]
UroToday.com - In this study we report an analysis of prostate cancer grade migration trends, by age, using Surveillance, Epidemiology, and End Results (SEER) data over a 30-year period from 1974 to 2003. Age and grade are critical factors in guiding treatment decision-making and outcomes reporting in prostate cancer.
Comparing Biochemical Relapse-Free Survival Between Primary Gleason Score 3 & Primary Gleason Score 4 For Biopsy Gleason Score 7 Prostate Cancer
Source: Prostate / Prostate Cancer News From Medical News Today [2008.11.29]
UroToday.com - We feel that this work is an important contribution to the literature as it compares outcomes across three different modalities. One aspect with which the authors struggled was how to address the poor outcomes for surgical patients. Three randomized trials have shown a biochemical benefit for adjuvant external beam radiation after surgery.
2008 Prostate Cancer Retreat Available Online - Prostate Cancer Foundation
Source: Cancer / Oncology News From Medical News Today [2008.11.27]
The Prostate Cancer Foundation (PCF) has made presentations from its 2008 Scientific Retreat available online. The PCF's annual retreat provides a forum to review advances in prostate cancer research aimed at reducing death and suffering from this prevalent men's disease. The three-day event was held in October at Incline Village, Nevada, and was attended by 293 of the world's leading physicians and scientists engaged in prostate cancer research.
Researchers Identify Novel Approach For Suppressing Prostate Cancer Development
Source: Prostate / Prostate Cancer News From Medical News Today [2008.11.26]
Researchers at the University of Southern California (USC) have found that inactivating a specific biomarker for aggressive prostate cancer blocks the development of prostate cancer in animal models. Researchers say the upcoming study in the Proceedings of the National Academy of Sciences now available online may lead to a novel cancer therapy for humans. "This research has far-reaching implications in a wide range for human cancers," says Amy Lee, Ph.D.
USC Researchers Identify Novel Approach For Suppressing Prostate Cancer Development
Source: Prostate / Prostate Cancer News From Medical News Today [2008.11.25]
Inactivation of a specific protein associated with cancer development halts prostate tumor progression in animal model Los Angeles, Calif. Nov. 24, 2008 California (USC) have found that inactivating a specific biomarker for aggressive prostate cancer blocks the development of prostate cancer in animal models. Researchers say the finding of the upcoming study in the Proceedings of the National Academy of Sciences therapy for humans.
Inverse Association Between Histologic Inflammation In Needle Biopsy Specimens And Prostate Cancer In Men With Serum PSA Of 10-50 Ng/ML
Source: Prostate / Prostate Cancer News From Medical News Today [2008.11.24]
UroToday.com - In the online edition of Urology, Dr. Tomoaki Terakawa and associates reported on parameters that may help determine whether a man with a PSA between 10 and 50ng/ml with a negative prostate biopsy is likely to have prostate cancer (CaP) later on. Specifically, they evaluated the role of histological inflammation on the biopsy specimen as a cause of the elevated PSA.
Prediagnostic BMI, Plasma C-Peptide Concentration, And Prostate Cancer-Specific Mortality In Men With Prostate Cancer: A Long-Term Survival Analysis
Source: Prostate / Prostate Cancer News From Medical News Today [2008.11.24]
UroToday.com - A significant level of interest has developed in the association of prostate cancer (CaP) specific mortality (PCSM) with nutrition, lifestyle variables, and treatment effects. The data surrounding a man's body mass index (BMI) and PCSM is mixed, but likely suggest an association between high BMI and an increased risk of dying from CaP. But is there a test that links obesity with this increased risk? In the online edition of Lancet Oncology, Dr. Jing Ma and associates of Dr.
Growing Number Of Young Prostate Cancer Patients Need 'sexual Rehabilitation'
Source: Erectile Dysfunction / Premature Ejaculation News From Medical News Today [2008.11.18]
Prostate cancer is being detected and treated at an earlier age, resulting in more cases of erectile dysfunction in younger men. While for many this is a temporary setback, for some it can take much longer and others will never recover their former capability. Dr Michael Lowy from Sydney Men's Health, said the result was a growing demand for "sexual rehabilitation" services, an evolving scientific and clinical branch of sexual medicine and urology.
Genetic Risk Factors May Tailor Prostate Cancer Screening Approaches
Source: Prostate / Prostate Cancer News From Medical News Today [2008.11.18]
Men with a family history of prostate cancer and African-American men are particularly susceptible to the disease, with a twofold to sevenfold increased risk. Assessing risk in these populations has been difficult. "There have been years of effort to try to identify genes and genetic mutations associated with prostate cancer as there are for breast cancer," said Veda N. Giri, M.D.
Diabetes drugs tied to lower prostate cancer risk (Reuters)
Source: Y! Health Prostate Cancer News [2008.11.18]
Reuters - Drugs used to control diabetes may lower the risk of prostate cancer, investigators at the University of Tampere in Finland report.
Gene Screen Might Predict Prostate Cancer
Source: MedicineNet Cancer Prevention Specialty [2008.11.18]
Title: Gene Screen Might Predict Prostate Cancer
Category: Health News
Created: 11/18/2008 2:00:00 AM
Last Editorial Review: 11/18/2008
Gene Screen Might Predict Prostate Cancer (HealthDay)
Source: Y! Health Prostate Cancer News [2008.11.17]
HealthDay - MONDAY, Nov. 17 (HealthDay News) -- Doctors may someday be able
to use five genetic markers to assess whether a man is at high risk to
develop prostate cancer, a new study suggests.
Aspirin may mask prostate cancer, study hints (Reuters)
Source: Y! Health Prostate Cancer News [2008.11.17]
Reuters - Middle-aged men who take aspirin or other "nonsteroidal anti-inflammatory drug" (NSAID) have significantly lower levels of a blood protein used to spot prostate cancer than men who don't take these widely used drugs, a study shows.
New Findings Offer Fresh Hope To Men With Prostate Cancer That Has Returned After Attempted Cure
Source: Prostate / Prostate Cancer News From Medical News Today [2008.11.16]
The link between the PSA (prostate-specific antigen) blood test and the detection of prostate cancer is well-established. In new findings released publicly for the first time today, Australian and New Zealand researchers have demonstrated how two serial measures of PSA can be used to accurately predict a patient's prognosis when prostate cancer returns after attempted cure.
Treatment Of Patients After Failed High Intensity Focused Ultrasound And Radiotherapy For Localized Prostate Cancer
Source: Prostate / Prostate Cancer News From Medical News Today [2008.11.16]
UroToday.com - One of the international leaders in laparoscopic radical prostatectomy, Jens-Uwe Stozenburg from Leipzig, Germany and associates has reported on the use of salvage laparoscopic extra-peritoneal radical prostatectomy (EERPE) following failed high intensity focused ultrasound therapy (HIFU), external beam radiotherapy (ERBT) or brachytherapy.
Agent Orange exposure linked to prostate cancer (Reuters)
Source: Y! Health Prostate Cancer News [2008.11.10]
Reuters - A study of Vietnam War era veterans shows that exposure to Agent Orange is associated with more than a two-fold increased risk of prostate cancer, earlier disease onset, and prostate cancer with more aggressive features.
Statins Lower Blood Marker for Prostate Cancer
Source: MedicineNet Mens Health Specialty [2008.10.31]
Title: Statins Lower Blood Marker for Prostate Cancer
Category: Health News
Created: 10/31/2008 2:00:00 AM
Last Editorial Review: 10/31/2008
Statins Lower Prostate Cancer Marker
Source: MedicineNet Prostate Cancer Specialty [2008.10.29]
Title: Statins Lower Prostate Cancer Marker
Category: Health News
Created: 10/29/2008
Last Editorial Review: 10/29/2008
Prostate Cancer Prevention Study Halted
Source: MedicineNet Prostate Cancer Specialty [2008.10.29]
Title: Prostate Cancer Prevention Study Halted
Category: Health News
Created: 10/29/2008
Last Editorial Review: 10/29/2008
Rethinking Prostate Cancer in Older Men
Source: MedicineNet Skin Cancer Specialty [2008.10.20]
Title: Rethinking Prostate Cancer in Older Men
Category: Health News
Created: 10/18/2008 2:00:00 AM
Last Editorial Review: 10/20/2008
ASTRO: Rectum Changes During Prostate Cancer Radiation May Affect Therapy
Source: MedPage Today Radiology [2008.09.30]
BOSTON (MedPage Today) -- Because the size and shape of the rectum can change after the start of high-dose radiotherapy for prostate cancer, reliance on pretreatment CT for planning may underestimate the radiation toxicity, investigators reported here.
ASTRO: Proton Radiation Fails to Impress in Prostate Cancer Study
Source: MedPage Today Radiology [2008.09.26]
BOSTON (MedPage Today) -- Proton radiation for prostate cancer had an acceptable tolerability profile but produced little evidence of a "gee whiz" impact to justify its cost, according to preliminary results from a phase I/II clinical trial.
Drug Can Slow Bone Loss in Prostate Cancer Patients
Source: MedicineNet alendronate Specialty [2008.09.19]
Title: Drug Can Slow Bone Loss in Prostate Cancer Patients
Category: Health News
Created: 9/19/2008 2:00:00 AM
Last Editorial Review: 9/19/2008
Study Links Serum Calcium, Prostate Cancer Death
Source: MedicineNet Cancer Causes Specialty [2008.09.04]
Title: Study Links Serum Calcium, Prostate Cancer Death
Category: Health News
Created: 9/4/2008 2:00:00 AM
Last Editorial Review: 9/4/2008
Study Links Agent Orange to Prostate Cancer in Vietnam Vets
Source: MedicineNet Asbestos-Related Disorders Specialty [2008.08.07]
Title: Study Links Agent Orange to Prostate Cancer in Vietnam Vets
Category: Health News
Created: 8/7/2008 2:00:00 AM
Last Editorial Review: 8/7/2008
Prostate Cancer Therapy May Not Help
Source: MedicineNet leuprolide Specialty [2008.07.09]
Title: Prostate Cancer Therapy May Not Help
Category: Health News
Created: 7/9/2008
Last Editorial Review: 7/9/2008
Prostate Cancer Screening
Source: MedicineNet Benign Prostatic Hyperplasia Specialty [2008.06.09]
Title: Prostate Cancer Screening
Category: Procedures and Tests
Created: 6/9/2008
Last Editorial Review: 6/9/2008
Lowering Cholesterol May Also Lower Prostate Cancer Risk
Source: MedicineNet Prostate Specific Antigen Specialty [2008.05.22]
Title: Lowering Cholesterol May Also Lower Prostate Cancer Risk
Category: Health News
Created: 5/22/2008 2:00:00 AM
Last Editorial Review: 5/22/2008
Radiation for Prostate Cancer Raises Risk of Other Cancers
Source: MedicineNet Bladder Cancer Specialty [2008.05.20]
Title: Radiation for Prostate Cancer Raises Risk of Other Cancers
Category: Health News
Created: 5/20/2008 2:00:00 AM
Last Editorial Review: 5/20/2008
Prostate Cancer Vaccine Looks Promising in Early Trial
Source: MedicineNet Prostate Specific Antigen Specialty [2008.05.19]
Title: Prostate Cancer Vaccine Looks Promising in Early Trial
Category: Health News
Created: 5/19/2008 2:00:00 AM
Last Editorial Review: 5/19/2008
Genes Play Part in Prostate Cancer Among Races
Source: MedicineNet Prostate Specific Antigen Specialty [2008.05.16]
Title: Genes Play Part in Prostate Cancer Among Races
Category: Health News
Created: 5/16/2008 2:00:00 AM
Last Editorial Review: 5/16/2008
Celebrex Plus Lipitor Could Fight Prostate Cancer
Source: MedicineNet celecoxib Specialty [2008.04.15]
Title: Celebrex Plus Lipitor Could Fight Prostate Cancer
Category: Health News
Created: 4/15/2008 2:00:00 AM
Last Editorial Review: 4/15/2008
Did Medicare Reimbursement Changes Affect Prostate Cancer Treatment?
Source: MedicineNet Testicular Cancer Specialty [2008.04.08]
Title: Did Medicare Reimbursement Changes Affect Prostate Cancer Treatment?
Category: Health News
Created: 4/8/2008 2:00:00 AM
Last Editorial Review: 4/8/2008
Chemo Break Benefits Some Men With Prostate Cancer
Source: MedicineNet Hair Loss Specialty [2008.03.03]
Title: Chemo Break Benefits Some Men With Prostate Cancer
Category: Health News
Created: 3/1/2008 2:00:00 AM
Last Editorial Review: 3/3/2008
Drug Combo May Fight Prostate Cancer
Source: MedicineNet docetaxel Specialty [2008.02.19]
Title: Drug Combo May Fight Prostate Cancer
Category: Health News
Created: 2/19/2008
Last Editorial Review: 2/19/2008
Diet, Drugs May Stop Prostate Cancer
Source: MedicineNet finasteride Specialty [2007.09.25]
Title: Diet, Drugs May Stop Prostate Cancer
Category: Health News
Created: 9/25/2007
Last Editorial Review: 9/25/2007
Prostate Cancer
Source: MedicineNet Hydronephrosis Specialty [2007.06.04]
Title: Prostate Cancer
Category: Diseases and Conditions
Created: 12/31/1997
Last Editorial Review: 6/4/2007
Lifestyle, diet may stop or reverse prostate cancer progression
Source: The Doctors Lounge - Urology
The research is the first randomized, controlled trial to show that lifestyle changes may affect cancer progression.
Diffusion And Perfusion MR Imaging Of The Prostate
Source: MRI / PET / Ultrasound News From Medical News Today [2008.11.29]
UroToday.com - The current gold standard for diagnosis of prostate cancer is the Transrectal Ultrasound (TRUS) guided prostate biopsy, initiated by elevated PSA-levels or a Digital Rectal Examination (DRE) suspicious for prostate cancer. However TRUS and TRUS-guided biopsies are known to have high false-negative rates, up to 30% with random sextant biopsies 1, 2.
EMR At 1.5 Tesla To Assess Local Recurrence After Radical Prostatectomy Using T2-Weighted & Contrast-Enhanced Imaging
Source: Prostate / Prostate Cancer News From Medical News Today [2008.11.24]
UroToday.com - Imaging accuracy for local recurrence of prostate cancer (CaP) and the use of endorectal magnetic resonance (eMR) has not been significantly assessed. In the online version of European Radiology, Dr. Stefano Cirillo and colleagues from Italy evaluated the diagnostic performance of eMR for diagnosing local CaP recurrence following radical prostatectomy (RP) in the face of an increasing serum PSA level.
Significantly Lower PSA Levels Discovered In Men Who Take Aspirin
Source: Prostate / Prostate Cancer News From Medical News Today [2008.11.18]
The use of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) is significantly associated with lower PSA levels, especially among men with prostate cancer, say researchers at Vanderbilt University. This large analysis known as the Nashville Men's Health Study included 1,277 participants referred to a urologist for a biopsy of their prostate. Approximately 46 percent of the men reported taking an NSAID, mostly aspirin (37 percent of all men).
Cardium's InnerCool Announces New Tissue-Specific UroCool(TM) System For Use In Prostate Surgeries
Source: Prostate / Prostate Cancer News From Medical News Today [2008.11.17]
Cardium Therapeutics (Amex: CXM) and its operating unit InnerCool Therapies, Inc., today announced that it has developed a pelvic cooling catheter system called UroCool(TM), which is designed to induce localized cooling during surgery for prostate cancer (radical prostatectomy). The new technology is being applied in collaboration with renowned prostate surgeon, Thomas E. Ahlering, M.D.
Cancer Treatment May Result In Bone Loss
Source: Bones / Orthopaedics News From Medical News Today [2008.11.16]
New cross-Canada study in Journal of Clinical Oncology outlines risks A new cross-Canada study has found that breast and prostate cancer treatment can foster bone loss. In the online edition of the Journal of Clinical Oncology, the scientists explain how loss of bone mass might affect 46,000 people diagnosed with breast and prostate cancer each year* and place them at increased risk for osteoporosis and fractures.
The Influence Of Statin Medications On Prostate-specific Antigen Levels
Source: Cholesterol News From Medical News Today [2008.11.15]
UroToday.com - According to a report by Dr. Robert J. Hamilton and associates that appears in the November 5, 2008 issue of the Journal of the National Cancer Institute, statin use lowers PSA levels, and as a result may confound the detection of prostate cancer (CaP) in these patients. Statins are lipid-lowering agents in widespread use in the US. Several reports suggest that men on statins have a reduction in the risk of advanced CaP that ranges from 25% to 75%.
Prevalence Of A Tertiary Gleason Grade And Its Impact On Adverse Histopathologic Parameters In A Contemporary Radical Prostatectomy Series
Source: Prostate / Prostate Cancer News From Medical News Today [2008.11.15]
UroToday.com - Almost 40 years ago, Donald F. Gleason pioneered his well acknowledged grading system of prostate adenocarcinoma. In the ensuing years, the reliability of the Gleason system in predicting the outcomes of patients with prostate cancer (PCa) undergoing surgery, radiation therapy or surveillance has been proven in several single and multi-institutional studies. In its original version, the Gleason system considered only the two most predominant Gleason patterns.
Cancer Treatment May Result In Bone Loss - New Cross Canada Study
Source: Bones / Orthopaedics News From Medical News Today [2008.11.14]
A new cross-Canada study has found that breast and prostate cancer treatment can foster bone loss. In the online edition of the American Society of Clinical Oncology, the scientists explain how loss of bone mass might affect 46,000 people diagnosed with breast and prostate cancer each year* and place them at increased risk for osteoporosis and fractures. "Our study also looked at possible medications that can reverse or halt bone loss," says Dr.
Reduction In Prostate Specific Antigen Levels Associated With Statin Use
Source: Statins News From Medical News Today [2008.10.29]
Use of cholesterol-lowering statins is associated with a statistically significant decline in prostate specific antigen (PSA) levels, according to a report in the October 28 online issue of the Journal of the National Cancer Institute. Previous studies examined whether statin use was associated with a reduction in prostate cancer risk. The results, however, have been inconsistent. Few studies have examined the association between statins and PSA level.
Urology Week, 15-19 September, Asks Attention For Urological Conditions
Source: Erectile Dysfunction / Premature Ejaculation News From Medical News Today [2008.09.10]
Every year 346,000 new cases of prostate cancer are detected in Europe, every day 240 men die of the condition. At least 1 in 10 people age 65 or older suffers from urinary incontinence, the involuntary loss of urine. And epidemiologic data indicate that erectile dysfunction (ED) is a significant problem among men worldwide. As many as 42.8 million men are expected to suffer from ED in Europe alone in 2025.
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