Plegisol (Calcium Chloride / Magnesium Chloride / Potassium Chloride / Sodium Chloride Intra-Arterial) - Drug Interactions, Contraindications, Overdosage

DRUG INTERACTIONS

Drug Interactions

Additives may be incompatible. Consult with pharmacist, if available. When introducing additives, use aseptic technique, mix thoroughly and do not store. (See INSTRUCTIONS FOR USE.)

OVERDOSAGE

Overzealous instillation of the solution may result in unnecessary dilatation of the myocardial vasculature and leakage into the perivascular myocardium, possibly causing tissue edema. (SEE WARNINGS, PRECAUTIONS, and ADVERSE REACTIONS.)

CONTRAINDICATIONS

Plegisol must not be administered without the addition of 8.4% Sodium Bicarbonate Injection, USP, Hospira List 4900.

NOT FOR INTRAVENOUS INJECTION.

This solution is only for instillation into cardiac vasculature after buffering with sodium bicarbonate.