PLASMANATE SUMMARY
This product has been prepared from large pools of human plasma. Each 100 mL of Plasma Protein Fraction (Human) 5%, USP--Plasmanate® contains 5 g selected plasma proteins buffered with sodium carbonate and stabilized with 0.004 M sodium caprylate and 0.004 M acetyltryptophan. The plasma proteins consist of approximately 88% normal human albumin, 12% alpha and beta globulins and not more than 1% gamma globulin as determined by electrophoresis.1 The concentration of these proteins is such that this solution is iso-oncotic with normal human plasma and is isotonic. The approximate concentrations of the significant electrolytes in Plasmanate are: sodium 145 mEq/L, potassium 0.25 mEq/L, and chloride 100 mEq/L. Plasmanate must be administered intravenously.
Treatment of Shock
--Plasmanate is indicated in the treatment of shock due to burns, crushing injuries, abdominal emergencies, and any other cause where there is a predominant loss of plasma fluids and not red blood cells. It is also effective in the emergency treatment of shock due to hemorrhage.3,4 Following the emergency phase of therapy, blood transfusions may be indicated depending on the severity of the blood loss.
In infants and small children, Plasmanate has been found to be very useful in the initial therapy of shock due to dehydration and infection.
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PLASMANATE NEWS HIGHLIGHTS Media Articles Related to Plasmanate (Plasma Protein Fraction)
Study Shows Shocking Cost Of Multiple Sclerosis
Source: Multiple Sclerosis News From Medical News Today [2008.11.25]
Shocking Pictures To Appear On Cigarette Packets In UK On 1st October
Source: Erectile Dysfunction / Premature Ejaculation News From Medical News Today [2008.09.27]
Shock (Medical)
Source: MedicineNet Hyperthermia Specialty [2007.11.07]
Shock wave therapy for kidney stones linked to diabetes
Source: The Doctors Lounge - Urology
Still No Progress: Mixed Sex Wards And Racial Inequalities, UK
Source: Mental Health News From Medical News Today [2008.11.28]
Published Studies Related to Plasmanate (Plasma Protein Fraction)
Some biochemical parameters of blood plasma of turkey-hens following administration of 1,2,4-triasole derivative. [2007]
A prospective randomized control study to compare the effect of serum and a commercial serum substitute (Plasmanate) on the outcome of assisted reproduction program. [1998.02]
Randomised controlled trial of plasma protein fraction versus dopamine in hypotensive very low birthweight infants. [1993.09]
Plasmanate as a medium supplement for in vitro fertilization. [1993.01]
Hydroxyethyl starch: an alternative to plasma for postoperative volume expansion after cardiac surgery. [1988.07]
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