NEWS HIGHLIGHTSMedia Articles Related to Plan B (Levonorgestrel)
California Legislature Takes Up Multiple Health Care Bills
Source: Cleft Palate News From Medical News Today [2008.06.05]
"More than a dozen health bills are advancing through the [California] Legislature," some of which contain elements of a health care overhaul plan backed by Gov. Arnold Schwarzenegger (R) that passed the state Assembly but was rejected in the Senate earlier this year, the
US funding revamps African contraceptive drive (AFP)
Source: Y! Health News Search RSS Feed [2009.11.18]
AFP - A new 12 million dollar family planning drive launched here Wednesday highlights how Obama administration funding has revamped a contraception drive in Africa and developing states, UN officials said, noting a sharp turnaround from the Bush era.
Terrence Higgins Trust Welcomes Department Of Health Nursing Degree Announcement, UK
Source: HIV / AIDS News From Medical News Today [2009.11.15]
HIV and sexual health charity Terrence Higgins Trust has welcomed the announcement by the Department of Health that all new nurses will be educated to degree level from 2013. Terrence Higgins Trust (THT) currently employs nurses who work in Chlamydia screening programmes for young people, HIV testing clinics and clinics that offer contraception services and screening for sexually transmitted infections.
Published Studies Related to Plan B (Levonorgestrel)
Prevention of tamoxifen induced endometrial polyps using a levonorgestrel releasing intrauterine system long-term follow-up of a randomised control trial. [2009.09]
OBJECTIVES: In a RCT, we have previously shown that the levonorgestrel intrauterine system (LNG-IUS, Mirena) produces a decidual response protecting the endometrium at one year follow-up. We here report on the long-term follow-up of this group of women, to test the hypothesis that a LNG-IUS could prevent the pro-proliferative uterine responses of tamoxifen for up to 4.5 years... CONCLUSION: This study confirms that LNG-IUS induces benign endometrial changes and prevents endometrial polyps but only during its use in women taking tamoxifen. Endometrial thickness is a risk factor for the development of polyps.
The effect of levonorgestrel-releasing intrauterine device on menorrhagia in women taking anticoagulant medication after cardiac valve replacement. [2009.08]
BACKGROUND: This study was conducted to evaluate the effect of levonorgestrel-releasing intrauterine devices (LNG-IUDs) on menorrhagia in patients receiving anticoagulant therapy after cardiac valve replacement... CONCLUSION: LNG-IUDs can be considered as an effective non-surgical treatment for menorrhagia in women receiving anticoagulant therapy after cardiac valve replacement.
Effects of doxycycline on serum and endometrial levels of MMP-2, MMP-9 and TIMP-1 in women using a levonorgestrel-releasing subcutaneous implant. [2009.06]
BACKGROUND: Endometrial spotting and/or bleeding (ESB) occurs in levonorgestrel subcutaneous implant (LNG SI) users. Matrix metalloproteinases (MMPs) may play a role in ESB... CONCLUSION: LNG SI increased serum MMP-9 and TIMP-1 levels, while DOX decreased both serum and endometrial MMP-9 levels.
A Canadian, multicentre study comparing the efficacy of a levonorgestrel-releasing intrauterine system to an oral contraceptive in women with idiopathic menorrhagia. [2009.04]
OBJECTIVES: To evaluate the efficacy of a levonorgestrel-releasing intrauterine system (LNG-IUS) compared with a combined oral contraceptive containing 1 mg norethindrone acetate and 20 mg ethinyl estradiol (OC1/20) in reducing menstrual blood loss (MBL) in women with idiopathic menorrhagia... CONCLUSION: Both the LNG-IUS and the combined oral contraceptive effectively decreased menstrual blood loss in women with idiopathic menorrhagia. The overall clinical benefit was more pronounced with LNG-IUS than with OC1/20.
Uterine ultrasonographic changes during endometriosis treatment: a comparison between levonorgestrel-releasing intrauterine devices and a gonadotropin-releasing hormone agonist. [2008.12]
We compared the effects of levonorgestrel-releasing intrauterine devices (LNG-IUD) and a gonadotropin-releasing hormone agonist (GnRHa) on uterine volume, uterine arteries pulsatility index (PI) and endometrial thickness before and after six months of endometriosis treatment...
Clinical Trials Related to Plan B (Levonorgestrel)
Specific Care and Assistance Plan for Alzheimer's Disease [Completed]
The main objective of this work is to assess the feasibility and efficacy of a specific Care
and Assistance Plan for Alzheimer's disease (PLASA). The main outcome measure selected is
incapacity in carrying out the basic activities of daily living, evaluated by the ADCS-ADL
scale .
The PLASA was developed by a working group appointed by the Direction Générale de la Santé as
part of the government programme of action on Alzheimer's disease (October 2001, Ministère de
l'Emploi et de la Solidarité).
RCT of a Written Action Plan vs. Usual Care in Children With Acute Asthma [Completed]
The objective of the proposed large, high-intensity, randomised controlled trial is to
evaluate the real-life effectiveness of providing a written action plan to asthmatic children
discharged from the emergency department (ED) or hospital on the short-term adherence to
written recommendations (including medication, attendance to asthma education and medical
follow-up). main outcome is adherence to prescribed inhaled preventive medication measured
by an electronic counter. Secondary outcomes include attendance to asthma education and to
medical follow-up, serving by pharmacy of prescription of oral steroids, as well as asthma
control measured by questionnaire (Asthma Quiz for Kidz),2 use of rescue ß2-agonists, relapse
to emergency room.
Comparison of Tomotherapy Versus Intensity-Modulated Step-and-Shoot and Conventional Radiation Treatment Plans for Patients With Locally-Advanced Squamous Cell Carcinoma of the Cervix [Completed]
Standard treatment for non-operable cervix cancer is radiation and chemotherapy. This
treatment combination can result in significant radiation side-effects involving the bladder,
small bowel and rectum. To improve results with radiation/chemotherapy, higher radiation
doses have been tried for cervix cancer patients. Results from using higher radiation doses
show that cervix tumours may be better controlled, but the radiation side-effects are
worsened. Intensity modulated radiotherapy (IMRT) and Tomotherapy are new radiation planning
and delivery technologies which may allow for delivery of higher radiation doses with less
damage to normal organs. The purpose of this project is to determine whether or not IMRT
and/or Tomotherapy technology can produce radiation plans that deliver higher doses of
radiation to the tumor and lower doses to normal organs when compared to standard radiation
plans. The results from this project will provide the basis for possibly treating future
cervix cancer patients with Tomotherapy and providing them with improved cure rates along
with decreased rates of radiation side effects. No patients will be treated on this
protocol, as the investigators plan to only compare radiation dose calculations from
different treatment plans created for test cervix cancer cases. There will be absolutely no
patient contact in this protocol.
Written Treatment Plan Versus Usual Care for Treating Individuals With Asthma [Recruiting]
The overall goal of this randomized, controlled study is to compare a model written treatment
plan with the usual care that is provided by a group of adult and pediatric pulmonologists
and allergists in their practice settings. The written treatment plan is a form that allows a
treatment regimen that is consistent with National Heart, Lung, and Blood Institute (NHLBI)
guidelines to be conveyed to patients. Barriers to the use of written plans will be
identified to better understand why some patients and physicians use written treatment plans
more frequently and effectively than others. An additional goal is to assess how patients
from different racial/ethnic backgrounds utilize treatments plans. Because asthma
disproportionately affects African American and Latino patients, another goal of this study
is to better understand if there are fundamental differences in the way patients from
racial/ethnic minority groups self-manage asthma in comparison to their white counterparts.
The study will also try to determine if differences exist in the way physicians care for
minority patients. If there are differences, it is important to determine if the disparities
can be overcome with the use of a written treatment plan form.
Advance Supply of Emergency Contraception Compared to Routine Postpartum Care in Teens [Active, not recruiting]
This is a pilot randomized controlled trial to asses the effects of advanced supply of
emergency contraception versus routine care in a teen postpartum population. The goals are
to assess feasibility of recruiting and retaining postpartum teens; to obtain estimates of
the prevalence of (use of Plan B, primary contraceptive continuation, unprotected intercourse
exposure, and pregnancy rates), in postpartum teens given advanced supply of Plan B; to
assess whether or not (lack of use of Plan B, contraceptive method non-continuation, and
unprotected intercourse exposure), are surrogate markers for risk of unintended pregnancy.
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