Media Articles Related to Plan B One-Step (Levonorgestrel)
Actavis and Medicines360 announce FDA approval of LILETTA (levonorgestrel-releasing intrauterine system)
Source: Sexual Health / STDs News From Medical News Today [2015.03.03]
Actavis plc, a leading global specialty pharmaceutical company, and Medicines360, a nonprofit women's health pharmaceutical company, have announced the approval of LILETTA (levonorgestrel-releasing...
'15 million unwanted pregnancies' created by low contraception in 35 poorer countries
Source: Abortion News From Medical News Today [2015.02.05]
Some 90% of the 16.7 million unwanted pregnancies across a third of the world's population every year are due to a failure to use modern contraception, study suggests.
Research reveals more than half of young women who have abortions were using contraception when they fell pregnant
Source: Abortion News From Medical News Today [2014.04.30]
Reproductive health charity Marie Stopes UK has launched the findings of the first research in the UK into the contraceptive use of women aged 16-24 having one or more abortions.
Contraceptive study seeks to reduce unintended pregnancies, Australia
Source: Medical Students / Training News From Medical News Today [2015.01.16]
A major four-year trial will offer GPs across Victoria specialised training on contraception to reduce the number of unintended pregnancies by increasing uptake of Long Acting Reversible...
New research shows a statistical significant association between increased LARC usage and reduction in teenage pregnancy and abortion rates in England
Source: Abortion News From Medical News Today [2014.11.27]
New findings, published in the International Journal of Women's Health, show increased long-acting reversible contraception (LARC) usage in England was significantly associated with decreased...
Published Studies Related to Plan B One-Step (Levonorgestrel)
An overview of four studies of a continuous oral contraceptive (levonorgestrel 90
mcg/ethinyl estradiol 20 mcg) on premenstrual dysphoric disorder and premenstrual
and premenstrual syndrome (PMS)... CONCLUSIONS: These data, although not consistent, indicate that continuous LNG/EE
Ethinyl estradiol and levonorgestrel pharmacokinetics with a low-dose transdermal contraceptive delivery system, AG200-15: a randomized controlled trial. [2011.11.29]
BACKGROUND: This study evaluated the ethinyl estradiol (EE) and levonorgestrel (LNG) pharmacokinetic profiles of AG200-15, a transdermal contraceptive delivery system, compared with a combination oral contraceptive (COC) containing EE 35 mcg and norgestimate 250 mcg... CONCLUSIONS: EE and LNG daily exposure during AG200-15 treatment was within the range reported for a low-dose COC. The daily EE dose with AG 200-15 was equivalent to a 30-mcg COC and was safe and well tolerated. Copyright (c) 2011 Elsevier Inc. All rights reserved.
Naproxen or estradiol for bleeding and spotting with the levonorgestrel intrauterine system: a randomized controlled trial. [2011.09.24]
OBJECTIVE: The purpose of this study was to evaluate whether oral naproxen or transdermal estradiol decreases bleeding and spotting in women who are initiating the levonorgestrel-releasing intrauterine system... CONCLUSION: The administration of naproxen resulted in a reduction in bleeding and spotting days compared with placebo. Copyright A(c) 2011 Mosby, Inc. All rights reserved.
Immediate versus delayed insertion of the levonorgestrel-releasing intrauterine device following dilation and evacuation: a randomized controlled trial. [2011.09.13]
BACKGROUND: The study was conducted to compare 6-month usage of the levonorgestrel-releasing intrauterine device (LNG-IUD) when placed immediately or 3 to 6 weeks after dilation and evacuation (D&E) procedure... CONCLUSION: Significantly more participants had the LNG-IUD placed in the immediate insertion group compared with the delayed insertion group. Given the low risk of complications, immediate post-D&E insertion of the LNG-IUD should be offered, especially for populations that may have difficulty returning for follow-up. Copyright (c) 2011 Elsevier Inc. All rights reserved.
Efficacy and safety of a levonorgestrel enteric-coated tablet as an over-the-counter drug for emergency contraception: a Phase IV clinical trial. [2011.09]
BACKGROUND: An enteric-coated levonorgestrel emergency contraceptive pill (E-LNG-ECP) is an improved formulation, in terms of side effects, which both dissolves and is absorbed in the intestine. Our aim was to evaluate the efficacy and safety of E-LNG-ECP as an over-the-counter (OTC) drug for emergency contraception (EC) in Chinese women... CONCLUSIONS: The study found that E-LNG-ECP was effective, safe and well tolerated as an OTC drug. However, an randomized controlled trial should be performed to compare standard LNG tablets with E-LNG-ECP.
Clinical Trials Related to Plan B One-Step (Levonorgestrel)
Medifast 5 & 1 Plan [Not yet recruiting]
The purpose of this study is to compare the effectiveness of the Medifast 5 & 1 Plan to a
food-based, reduced-energy diet plan. The study will be conducted over 52 weeks, including a
26-week weight-loss phase and a 26-week weight-maintenance phase. 120 participants will be
enrolled, with 60 randomized to the Medifast 5 & 1 Plan and 60 randomized to food-based,
reduced-energy diet plan. Multiple measures will be performed at baseline, 26 weeks, and 52
weeks, including anthropometry, body composition, blood pressure, blood assays, and appetite
Planned CORR: Planned Care for Obesity and Risk Reduction [Recruiting]
The researchers propose a randomized controlled trial to evaluate how well an intervention,
Planned Care for Obesity & Risk Reduction (Planned CORR), supports primary care treatment of
obesity in adults with at least one cardiovascular risk factor (CVRF).
Comparing Asthma Action Plans for Pediatric Asthma [Recruiting]
The purpose of this study is to evaluate and compare the relative effectiveness of two
asthma action plans (pictorial versus written) in terms of asthma action plan knowledge,
medication use, and family satisfaction with asthma education.
The Electronic Asthma Action Plan System for Implementation in Primary Care [Recruiting]
Asthma is a common and potentially fatal chronic disease. An asthma action plan (AAP) is a
written plan produced by a physician for a patient with asthma, to provide education and
guidelines for self-management of worsening asthma symptoms. Studies have shown that AAPs
effectively improve asthma control, but physicians fail to provide AAPs due to lack of time
and adequate skills. The investigators propose to develop a computerized tool that will
automatically generate an electronic version of the AAP, based on patient responses to
questions about their current asthma control. The investigators hope that this system will
eliminate the barriers that physicians face in delivery of an AAP and will increase the
frequency with which physicians are able to deliver AAPs to patients with asthma. The
objectives of the study are to determine the impact of an electronic asthma action plan
system on asthma action plan delivery by primary care physicians, to determine the impact of
an electronic asthma action plan system on patient hospitalisations, emergency room (ER)
visits, unscheduled visits to the doctor, total visits to the doctor, days off work or
school, nocturnal asthma symptoms, daytime asthma symptoms, daytime rescue puffer use, and
quality of life , and to measure physicians' perceptions of and satisfaction with the
Improving Parent Understanding of Instructions About Asthma Care [Recruiting]
Asthma has an especially great impact on poor urban children and their families. In
addition to higher asthma prevalence and morbidity, those in low SES urban areas are at risk
for low health literacy. Low health literacy is associated with poorer asthma outcomes.
The provision of a written asthma action plan has been shown to help with asthma management
and to reduce hospitalizations and ER visits. Poor urban families who may have low literacy
may need an alternative asthma action plan to convey the treatment plan.
This pilot study proposes to investigate whether a plain language asthma action plan can
improve parent understanding and adherence with medication instructions, compared to
standard written materials, among parents of children with asthma. This is an RCT in which
parents of children with asthma will be randomized to either receive a pictogram-based low
literacy asthma action plan, or a standard action plan (AAAAI), to examine whether those who
receive the low literacy plan have improved asthma action plan knowledge when presented with
a hypothetical scenario.
A second part of the study is to examine whether providers who are given the pictogram-based
low literacy asthma action plan will be more likely to counsel about certain aspects of
asthma management (eg. need for daily medications even when sick, spacer use, confusion
between everyday and rescue inhaler)compared to providers who receive use a standard action
plan (AAAAI). This is an RCT in which pediatric providers are randomized to counsel a
hypothetical patient using the pictogram-based action plan or the standard action plan
Reports of Suspected Plan B One-Step (Levonorgestrel) Side Effects
Menstruation Irregular (3534),
Pelvic Pain (665),
Menstruation Delayed (446),
Abdominal Pain (289),
Breast Tenderness (216), more >>