Pitocin (Oxytocin) - Side Effects and Adverse Reactions

ADVERSE REACTIONS

The following adverse reactions have been reported in the mother:

Anaphylactic reaction	Premature ventricular contractions
Postpartum hemorrhage	Pelvic hematoma
Cardiac arrhythmia	Subarachnoid hemorrhage
Fatal afibrinogenemia	Hypertensive episodes
Nausea	Rupture of the uterus
Vomiting

Excessive dosage or hypersensitivity to the drug may result in uterine hypertonicity, spasm, tetanic contraction, or rupture of the uterus.

The possibility of increased blood loss and afibrinogenemia should be kept in mind when administering the drug.

Severe water intoxication with convulsions and coma has occurred, associated with a slow oxytocin infusion over a 24-hour period. Maternal death due to oxytocin-induced water intoxication has been reported.

The following adverse reactions have been reported in the fetus or neonate:

Due to induced uterine motility:	Due to use of oxytocin in the mother:
Bradycardia	Low Apgar scores at five minutes
Premature ventricular contractions and other arrhythmias	Neonatal jaundice
Permanent CNS or brain damage	Neonatal retinal hemorrhage
Fetal death
Neonatal seizures have been reported with the use of Pitocin.

REPORTS OF SUSPECTED PITOCIN SIDE EFFECTS / ADVERSE REACTIONS

Possible Pitocin side effects / adverse reactions in 26 year old female

Reported by a consumer/non-health professional from United States on 2012-07-31

Patient: 26 year old female

Reactions: Procedural Pain, Foetal Growth Restriction, Maternal Exposure During Pregnancy, Drug Withdrawal Syndrome, Hypertension, Foetal Heart Rate Decreased, Postpartum Depression

Suspect drug(s):
Buprenorphine
    Indication: Drug Dependence
    Start date: 2010-01-01
    End date: 2011-11-01

Buprenorphine
    Start date: 2011-11-01
    End date: 2011-11-01

Buprenorphine
    Start date: 2011-11-01

Pitocin
    Dosage: unknown dosage details
    Indication: Induced Labour
    Start date: 2011-11-02
    End date: 2011-11-02

Other drugs received by patient: Zoloft; Multi-Vitamins; Biotin; Fish OIL

Possible Pitocin side effects / adverse reactions in 22 year old female

Reported by a health professional (non-physician/pharmacist) from India on 2012-08-14

Patient: 22 year old female

Reactions: Haemoglobin Decreased, Retained Placenta or Membranes

Suspect drug(s):
Pitocin

Possible Pitocin side effects / adverse reactions in 32 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-15

Patient: 32 year old female

Reactions: Postpartum Haemorrhage, Drug Ineffective

Suspect drug(s):
Pitocin