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Piroxicam (Piroxicam) - Side Effects and Adverse Reactions



In patients taking piroxicam capsules or other NSAIDs, the most frequently reported adverse experiences occurring in approximately 1 to 10% of patients are:
Cardiovascular System: Edema.
Digestive System: Anorexia, abdominal pain, constipation, diarrhea, dyspepsia, elevated liver enzymes, flatulence, gross bleeding/perforation, heartburn, nausea, ulcers (gastric/duodenal), vomiting.
Hemic and Lymphatic System: Anemia, increased bleeding time.
Nervous System: Dizziness, headache.
Skin and Appendages: Pruritus, rash.
Special Senses: Tinnitus.
Urogenital System: Abnormal renal function.
Additional adverse experiences reported occasionally include:
Body As a Whole: Fever, infection, sepsis.
Cardiovascular System: Congestive heart failure, hypertension, tachycardia, syncope.
Digestive System: Dry mouth, esophagitis, gastritis, glossitis, hematemesis, hepatitis, jaundice, melena, rectal bleeding, stomatitis.
Hemic and Lymphatic System: Ecchymosis, eosinophilia, epistaxis, leukopenia, purpura, petechial rash, thrombocytopenia.
Metabolic and Nutritional: Weight changes.
Nervous System: Anxiety, asthenia, confusion, depression, dream abnormalities, drowsiness, insomnia, malaise, nervousness, paresthesia, somnolence, tremors, vertigo.
Respiratory System: Asthma, dyspnea.
Skin and Appendages: Alopecia, bruising, desquamation, erythema, photosensitivity, sweat.
Special Senses: Blurred vision.
Urogenital System: Cystitis, dysuria, hematuria, hyperkalemia, interstitial nephritis, nephrotic syndrome, oliguria/polyuria, proteinuria, renal failure.
Other adverse reactions which occur rarely are:
Body As a Whole: Anaphylactic reactions, appetite changes, death, flu-like syndrome, pain (colic), serum sickness.
Cardiovascular System: Arrhythmia, exacerbation of angina, hypotension, myocardial infarction, palpitations, vasculitis.
Digestive System: Eructation, liver failure, pancreatitis.
Hemic and Lymphatic System: Agranulocytosis, hemolytic anemia, aplastic anemia, lymphadenopathy, pancytopenia.
Hypersensitivity: Positive ANA.
Metabolic and Nutritional: Hyperglycemia, hypoglycemia.
Nervous System: Akathisia, convulsions, coma, hallucinations, meningitis, mood alterations.
Respiratory: Respiratory depression, pneumonia.
Skin and Appendages: Angioedema, toxic epidermal necrosis, erythema multiforme, exfoliative dermatitis, onycholysis, Stevens-Johnson syndrome, urticaria, vesiculobullous reaction.
Special Senses: Conjunctivitis, hearing impairment, swollen eyes.


Below is a sample of reports where side effects / adverse reactions may be related to Piroxicam. The information is not vetted and should not be considered as verified clinical evidence.

Possible Piroxicam side effects / adverse reactions in 45 year old female

Reported by a physician from India on 2011-10-07

Patient: 45 year old female

Reactions: Death, Anaphylactic Reaction

Adverse event resulted in: death

Suspect drug(s):

Possible Piroxicam side effects / adverse reactions in 35 year old male

Reported by a physician from India on 2011-10-12

Patient: 35 year old male weighing 50.0 kg (110.0 pounds)

Reactions: Respiratory Rate Increased, Tachycardia, Chills, Aphasia, Anaphylactic Shock, Sensory Loss, Quadriparesis, Asthenia

Suspect drug(s):

Possible Piroxicam side effects / adverse reactions in 45 year old female

Reported by a consumer/non-health professional from Brazil on 2011-10-17

Patient: 45 year old female weighing 91.0 kg (200.2 pounds)

Reactions: Weight Increased, Blood Pressure Increased, Haemorrhage, Increased Appetite

Suspect drug(s):
    Dosage: 50 mg, 1x/day
    Administration route: Oral
    Indication: Major Depression
    Start date: 2011-03-14

    Dosage: unk
    Start date: 2011-08-01

    Indication: Depression

    Indication: Mania

See index of all Piroxicam side effect reports >>

Drug label data at the top of this Page last updated: 2011-04-25

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