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Piroxicam (Piroxicam) - Summary

Piroxicam Rx
Summary Description Indications and Dosage Warnings and Precautions Side Effects and Adverse Reactions Drug Interactions, Overdosage and Contraindications Clinical Pharmacology Other Rx Information Active Ingredients Adverse Event Reports
 

Piroxicam News
News in Media Published Studies Curr't Clinical Trials

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Cardiovascular Risk

  • NSAIDs1 may cause an increased risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal. This risk may increase with duration of use. Patients with cardiovascular disease or risk factors for cardiovascular disease may be at greater risk (see WARNINGS).
  • Piroxicam capsules are contraindicated for the treatment of peri-operative pain in the setting of coronary artery bypass graft (CABG) surgery (see WARNINGS).

Gastrointestinal Risk

  • NSAIDs cause an increased risk of serious gastrointestinal adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms. Elderly patients are at greater risk for serious gastrointestinal events (see WARNINGS).
1 Throughout this package insert, the term NSAID refers to a non-aspirin non-steroidal anti-inflammatory drug.
 

PIROXICAM SUMMARY

PIROXICAM CAPSULES USP

Piroxicam capsules contain piroxicam which is a member of the oxicam group of non-steroidal anti-inflammatory drugs (NSAIDs). Each dark green and olive capsule contains 10 mg piroxicam, each dark green capsule contains 20 mg piroxicam for oral administration.

Carefully consider the potential benefits and risks of piroxicam capsules and other treatment options before deciding to use piroxicam capsules. Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals (see WARNINGS).

Piroxicam capsules are indicated:

  • For relief of the signs and symptoms of osteoarthritis.
  • For relief of the signs and symptoms of rheumatoid arthritis.

PIROXICAM NEWS HIGHLIGHTS

Published Studies Related to Piroxicam

Double-blind, placebo-controlled, randomized clinical trial of sublingual or intramuscular piroxicam in the treatment of renal colic. A comparative study. [2007]

[Randomized study comparing piroxicam analgesia and tramadol analgesia during outpatient electromagnetic extracorporeal lithotripsy] [2006.04]

Sublingual piroxicam for postoperative analgesia: preoperative versus postoperative administration: a randomized, double-blind study. [2006.03]

Comparison of prednisolone with piroxicam in complex regional pain syndrome following stroke: a randomized controlled trial. [2006.02]

Clinical evaluation of piroxicam-FDDF and azithromycin in the prevention of complications associated with impacted lower third molar extraction. [2005.12]

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Clinical Trials Related to Piroxicam

A Double Blind, Double Dummy, Randomized, Comparative Study Of The Efficacy And Safety Of Valdecoxib 40 Mg Twice Daily, As Needed In The First Menstrual Cycle Day And Then Once A Day, And Piroxicam 40 Mg Once A Day In The Treatment Of Patients With Primary Dysmenorrhea [Completed]

Comparative Study of Olive Oil With Piroxicam Gel in Osteoarthritis of the Knee [Recruiting]

Interaction Between Antihypertensives and Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) [Completed]

Multi-Centre European Photopatch Test Study [Not yet recruiting]

Study of Lornoxicam or Ketorolac or Placebo for Post-Operative Pain After Bunionectomy [Completed]

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Page last updated: 2007-08-04

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