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Phytonadione (Phytonadione) - Side Effects and Adverse Reactions

 
 



ADVERSE REACTIONS

Severe hypersensitivity reactions, including anaphylactoid reactions and deaths have been reported following parenteral administration. The majority of these reported events occurred following intravenous administration (see Box Warning.)

The possibility of allergic sensitivity, including an anaphylactoid reaction, should be kept in mind following parenteral administration.

Transient "flushing sensations" and "peculiar" sensations of taste have been observed, as well as rare instances of dizziness, rapid and weak pulse, profuse sweating, brief hypotension dyspnea and cyanosis.

Pain, swelling, and tenderness at the injection site may occur.

Infrequently, usually after repeated injection, erythematous, indurated, pruritic plaques have occurred; rarely, these have progressed to scleroderma-like lesions that have persisted for long periods. In other cases, these lesions have resembled erythema perstans.

Hyperbilirubinemia has been observed in the newborn following administration of phytonadione. The has occurred rarely and primarily with doses above those recommended (See Precautions, Pediatric Use.)



REPORTS OF SUSPECTED PHYTONADIONE SIDE EFFECTS / ADVERSE REACTIONS

Below is a sample of reports where side effects / adverse reactions may be related to Phytonadione. The information is not vetted and should not be considered as verified clinical evidence.

Possible Phytonadione side effects / adverse reactions in 79 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2011-12-29

Patient: 79 year old male weighing 73.6 kg (161.9 pounds)

Reactions: Renal Impairment, Anaphylactic Reaction, Hepatic Failure

Suspect drug(s):
Phytonadione



Possible Phytonadione side effects / adverse reactions in female

Reported by a pharmacist from United States on 2011-12-30

Patient: female weighing 2.6 kg (5.7 pounds)

Reactions: Injection Site Haemorrhage, Injection Site Haematoma, Needle Issue

Suspect drug(s):
Phytonadione



Possible Phytonadione side effects / adverse reactions in 60 year old male

Reported by a pharmacist from United States on 2012-02-15

Patient: 60 year old male weighing 77.6 kg (170.7 pounds)

Reactions: Deep Vein Thrombosis

Suspect drug(s):
Factor VIIA
    Dosage: 1 mg; total; iv
    Indication: International Normalised Ratio Increased
    Start date: 2011-05-27
    End date: 2011-05-27

Factor VIIA
    Dosage: 1 mg; total; iv
    Indication: Extradural Haematoma
    Start date: 2011-05-27
    End date: 2011-05-27

Phytonadione
    Dosage: 5 mg; total; iv
    Indication: Extradural Haematoma
    Start date: 2011-05-27
    End date: 2011-05-27

Phytonadione
    Dosage: 5 mg; total; iv
    Indication: International Normalised Ratio Increased
    Start date: 2011-05-27
    End date: 2011-05-27

Profilnine SD
    Dosage: 3530 iu; total; iv
    Indication: International Normalised Ratio Increased
    Start date: 2011-05-27
    End date: 2011-05-27

Profilnine SD
    Dosage: 3530 iu; total; iv
    Indication: Extradural Haematoma
    Start date: 2011-05-27
    End date: 2011-05-27

Other drugs received by patient: Warfarin Sodium



See index of all Phytonadione side effect reports >>

Drug label data at the top of this Page last updated: 2009-12-16

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