PHRENILIN®: Each PHRENILIN® tablet for oral administration, contains Butalbital, USP 50 mg, Acetaminophen, USP 325 mg.
PHRENILIN® tablets and PHRENILIN® FORTE capsules are indicated for the relief of the symptom complex of tension (or muscle contraction) headache.
Evidence supporting the efficacy and safety of this combination product in the treatment of multiple recurrent headaches is unavailable. Caution in this regard is required because butalbital is habitforming and potentially abusable.
Media Articles Related to Phrenilin (Butalbital / Acetaminophen)
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Can acupuncture improve quality of life for people with traumatic brain injury-related headaches?
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A study comparing the effectiveness of usual care alone to usual care plus either auricular or traditional Chinese acupuncture in treating patients with headaches due to a previous traumatic brain...
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Published Studies Related to Phrenilin (Butalbital / Acetaminophen)
Sumatriptan-Naproxen and Butalbital: A Double-Blind, Placebo-Controlled Crossover Study. [2011.11.21]
Objectives.- The primary objective was to compare the efficacy of a sumatriptan and naproxen combination medication (SumaRT/Nap-85 mg sumatriptan and 500 mg naproxen sodium), a butalbital-containing combination medication (BCM-50 mg butalbital, 325 mg acetaminophen, 40 mg caffeine), and placebo when used to treat moderate to severe migraine headache pain in subjects who used BCMs in the past.
Butalbital in the treatment of headache: history, pharmacology, and efficacy. [2001.11]
Analgesics containing butalbital compounded with aspirin, acetaminophen, and/or caffeine are widely used for the treatment of migraine and tension-type headache. The butalbital-containing compounds are efficacious in placebo-controlled trials among patients with episodic tension-type headaches.Because of concerns about overuse, medication-overuse headache, and withdrawal, their use should be limited and carefully monitored.
Page last updated: 2016-07-25