PHRENILIN®: Each PHRENILIN® tablet for oral administration, contains Butalbital, USP 50 mg, Acetaminophen, USP 325 mg.
PHRENILIN® tablets and PHRENILIN® FORTE capsules are indicated for the relief of the symptom complex of tension (or muscle contraction) headache.
Evidence supporting the efficacy and safety of this combination product in the treatment of multiple recurrent headaches is unavailable. Caution in this regard is required because butalbital is habitforming and potentially abusable.
Media Articles Related to Phrenilin (Butalbital / Acetaminophen)
Vitamin D deficiency increases risk of chronic headache
Source: Headache / Migraine News From Medical News Today [2017.01.04]
Vitamin D deficiency may increase the risk of chronic headache, according to a new study from the University of Eastern Finland. The findings were published in Scientific Reports.
Source: MedicineNet Dehydration Specialty [2016.11.30]
Title: Headache Remedies
Category: Diseases and Conditions
Created: 4/12/2016 12:00:00 AM
Last Editorial Review: 11/30/2016 12:00:00 AM
Visits to pediatric emergency departments for headache pain in children are on the rise
Source: Headache / Migraine News From Medical News Today [2016.10.24]
At 1 hospital, rates of emergency department visits and subsequent hospital admission doubled over a 7-year period.
Can You Blame Your Headaches on Your Thyroid?
Source: MedicineNet Hypothyroidism Specialty [2016.09.30]
Title: Can You Blame Your Headaches on Your Thyroid?
Category: Health News
Created: 9/29/2016 12:00:00 AM
Last Editorial Review: 9/30/2016 12:00:00 AM
Headaches and Menopause: What's the Connection?
Source: Headache / Migraine News From Medical News Today [2016.09.29]
Headaches are among the symptoms some women report during menopause. Learn more about what causes them, what other symptoms occur, and treatment options.
Published Studies Related to Phrenilin (Butalbital / Acetaminophen)
Sumatriptan-Naproxen and Butalbital: A Double-Blind, Placebo-Controlled Crossover Study. [2011.11.21]
Objectives.- The primary objective was to compare the efficacy of a sumatriptan and naproxen combination medication (SumaRT/Nap-85 mg sumatriptan and 500 mg naproxen sodium), a butalbital-containing combination medication (BCM-50 mg butalbital, 325 mg acetaminophen, 40 mg caffeine), and placebo when used to treat moderate to severe migraine headache pain in subjects who used BCMs in the past.
Butalbital in the treatment of headache: history, pharmacology, and efficacy. [2001.11]
Analgesics containing butalbital compounded with aspirin, acetaminophen, and/or caffeine are widely used for the treatment of migraine and tension-type headache. The butalbital-containing compounds are efficacious in placebo-controlled trials among patients with episodic tension-type headaches.Because of concerns about overuse, medication-overuse headache, and withdrawal, their use should be limited and carefully monitored.
Page last updated: 2017-01-04