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Phrenilin (Butalbital / Acetaminophen) - Summary



PHRENILIN®: Each PHRENILIN® tablet for oral administration, contains Butalbital, USP 50 mg, Acetaminophen, USP 325 mg.

PHRENILIN® tablets and PHRENILIN® FORTE capsules are indicated for the relief of the symptom complex of tension (or muscle contraction) headache.

Evidence supporting the efficacy and safety of this combination product in the treatment of multiple recurrent headaches is unavailable. Caution in this regard is required because butalbital is habitforming and potentially abusable.

See all Phrenilin indications & dosage >>


Media Articles Related to Phrenilin (Butalbital / Acetaminophen)

17 Natural Headache Remedies and Headache Trigger Foods
Source: MedicineNet Dehydration Specialty [2016.04.12]
Title: 17 Natural Headache Remedies and Headache Trigger Foods
Category: Diseases and Conditions
Created: 4/12/2016 12:00:00 AM
Last Editorial Review: 4/12/2016 12:00:00 AM

New hope on headache 'worse than childbirth': world's first fast track clinic for cluster condition opens
Source: Headache / Migraine News From Medical News Today [2016.03.20]
Health experts today launch a world first as a major boost for people who suffer what is ranked the most painful medical condition known to humankind, with its pain described by a majority of...

Migraine Headache
Source: MedicineNet Antiphospholipid Syndrome Specialty [2016.03.02]
Title: Migraine Headache
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 3/2/2016 12:00:00 AM

Could IBS, migraines and tension headaches be genetically linked?
Source: Headache / Migraine News From Medical News Today [2016.02.24]
Researchers have uncovered a possible genetic link between irritable bowel syndrome, migraines and tension-type headaches in a new study.

Source: MedicineNet Anthrax Specialty [2015.11.13]
Title: Headache
Category: Diseases and Conditions
Created: 5/31/2002 12:00:00 AM
Last Editorial Review: 11/13/2015 12:00:00 AM

more news >>

Published Studies Related to Phrenilin (Butalbital / Acetaminophen)

Sumatriptan-Naproxen and Butalbital: A Double-Blind, Placebo-Controlled Crossover Study. [2011.11.21]
Objectives.- The primary objective was to compare the efficacy of a sumatriptan and naproxen combination medication (SumaRT/Nap-85 mg sumatriptan and 500 mg naproxen sodium), a butalbital-containing combination medication (BCM-50 mg butalbital, 325 mg acetaminophen, 40 mg caffeine), and placebo when used to treat moderate to severe migraine headache pain in subjects who used BCMs in the past.

Butalbital in the treatment of headache: history, pharmacology, and efficacy. [2001.11]
Analgesics containing butalbital compounded with aspirin, acetaminophen, and/or caffeine are widely used for the treatment of migraine and tension-type headache. The butalbital-containing compounds are efficacious in placebo-controlled trials among patients with episodic tension-type headaches.Because of concerns about overuse, medication-overuse headache, and withdrawal, their use should be limited and carefully monitored.

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Page last updated: 2016-04-12

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