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Phrenilin (Butalbital / Acetaminophen) - Summary



PHRENILIN®: Each PHRENILIN® tablet for oral administration, contains Butalbital, USP 50 mg, Acetaminophen, USP 325 mg.

PHRENILIN® tablets and PHRENILIN® FORTE capsules are indicated for the relief of the symptom complex of tension (or muscle contraction) headache.

Evidence supporting the efficacy and safety of this combination product in the treatment of multiple recurrent headaches is unavailable. Caution in this regard is required because butalbital is habitforming and potentially abusable.

See all Phrenilin indications & dosage >>


Media Articles Related to Phrenilin (Butalbital / Acetaminophen)

Headache Far More Common Stroke Symptom in Kids
Source: Medscape Critical Care Headlines [2017.02.23]
Headaches occur in close to half of children with ischemic stroke, much more often than among adults with stroke, and are most common with dissection and transient cerebral arteriopathy of childhood.
Medscape Medical News

Headache Common Stroke Symptom in Kids
Source: MedPage Today Cardiology [2017.02.23]
(MedPage Today) -- While pediatric stroke is rare, nearly half present with pain

Headaches Often Strike Before Strokes in Kids: Study
Source: MedicineNet Headache Specialty [2017.02.23]
Title: Headaches Often Strike Before Strokes in Kids: Study
Category: Health News
Created: 2/22/2017 12:00:00 AM
Last Editorial Review: 2/23/2017 12:00:00 AM

Headache far more common stroke symptom in children than adults
Source: Headache / Migraine News From Medical News Today [2017.02.22]
Headaches were present in nearly half of all children older than 3 years of age having a stroke. Headaches were most common in children with specific forms of blood vessel abnormalities.

Vitamin D deficiency increases risk of chronic headache
Source: Headache / Migraine News From Medical News Today [2017.01.04]
Vitamin D deficiency may increase the risk of chronic headache, according to a new study from the University of Eastern Finland. The findings were published in Scientific Reports.

more news >>

Published Studies Related to Phrenilin (Butalbital / Acetaminophen)

Sumatriptan-Naproxen and Butalbital: A Double-Blind, Placebo-Controlled Crossover Study. [2011.11.21]
Objectives.- The primary objective was to compare the efficacy of a sumatriptan and naproxen combination medication (SumaRT/Nap-85 mg sumatriptan and 500 mg naproxen sodium), a butalbital-containing combination medication (BCM-50 mg butalbital, 325 mg acetaminophen, 40 mg caffeine), and placebo when used to treat moderate to severe migraine headache pain in subjects who used BCMs in the past.

Butalbital in the treatment of headache: history, pharmacology, and efficacy. [2001.11]
Analgesics containing butalbital compounded with aspirin, acetaminophen, and/or caffeine are widely used for the treatment of migraine and tension-type headache. The butalbital-containing compounds are efficacious in placebo-controlled trials among patients with episodic tension-type headaches.Because of concerns about overuse, medication-overuse headache, and withdrawal, their use should be limited and carefully monitored.

more studies >>

Page last updated: 2017-02-23

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