PHRENILIN®: Each PHRENILIN® tablet for oral administration, contains Butalbital, USP 50 mg, Acetaminophen, USP 325 mg.
PHRENILIN® tablets and PHRENILIN® FORTE capsules are indicated for the relief of the symptom complex of tension (or muscle contraction) headache.
Evidence supporting the efficacy and safety of this combination product in the treatment of multiple recurrent headaches is unavailable. Caution in this regard is required because butalbital is habitforming and potentially abusable.
Media Articles Related to Phrenilin (Butalbital / Acetaminophen)
Headache: Questions To Ask Your Doctor About Headaches
Source: MedicineNet Chronic Pain Specialty [2014.12.09]
Title: Headache: Questions To Ask Your Doctor About Headaches
Category: Doctor's Views
Created: 7/15/2005 12:00:00 AM
Last Editorial Review: 12/9/2014 12:00:00 AM
The Worst Headache of Your Life: Brain Hemorrhage Symptoms
Source: MedicineNet Brain Aneurysm Specialty [2014.12.01]
Title: The Worst Headache of Your Life: Brain Hemorrhage Symptoms
Category: Doctor's Views
Created: 4/23/2010 12:00:00 AM
Last Editorial Review: 12/1/2014 12:00:00 AM
Differences in nerve structure and function may help to explain how migraine headaches occur
Source: Headache / Migraine News From Medical News Today [2014.11.06]
Migraine linked to defective 'insulation' around nerve fibers, suggests study in Plastic and Reconstructive SurgeryA new study shows cellular-level changes in nerve structure and function that...
Preliminary results further confirms the effectiveness of electroCore's non-invasive vagus nerve stimulation treatment for headache
Source: Headache / Migraine News From Medical News Today [2014.10.27]
Preliminary results of an open-label trial carried in the journal of Headache and Pain reported that a single treatment with electroCore's hand held non-invasive vagus nerve stimulation (nVNS)...
Bariatric surgery may be risk factor for severe headache
Source: Headache / Migraine News From Medical News Today [2014.10.23]
Spontaneous intracranial hypotension - a leaking of spinal fluid - causes severe headaches. Weight-loss surgery patients may be particularly at risk for this condition.
Published Studies Related to Phrenilin (Butalbital / Acetaminophen)
Sumatriptan-Naproxen and Butalbital: A Double-Blind, Placebo-Controlled Crossover Study. [2011.11.21]
Objectives.- The primary objective was to compare the efficacy of a sumatriptan and naproxen combination medication (SumaRT/Nap-85 mg sumatriptan and 500 mg naproxen sodium), a butalbital-containing combination medication (BCM-50 mg butalbital, 325 mg acetaminophen, 40 mg caffeine), and placebo when used to treat moderate to severe migraine headache pain in subjects who used BCMs in the past.
Butalbital in the treatment of headache: history, pharmacology, and efficacy. [2001.11]
Analgesics containing butalbital compounded with aspirin, acetaminophen, and/or caffeine are widely used for the treatment of migraine and tension-type headache. The butalbital-containing compounds are efficacious in placebo-controlled trials among patients with episodic tension-type headaches.Because of concerns about overuse, medication-overuse headache, and withdrawal, their use should be limited and carefully monitored.