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Phrenilin (Butalbital / Acetaminophen) - Summary



PHRENILIN®: Each PHRENILIN® tablet for oral administration, contains Butalbital, USP 50 mg, Acetaminophen, USP 325 mg.

PHRENILIN® tablets and PHRENILIN® FORTE capsules are indicated for the relief of the symptom complex of tension (or muscle contraction) headache.

Evidence supporting the efficacy and safety of this combination product in the treatment of multiple recurrent headaches is unavailable. Caution in this regard is required because butalbital is habitforming and potentially abusable.

See all Phrenilin indications & dosage >>


Media Articles Related to Phrenilin (Butalbital / Acetaminophen)

Migraine Headaches Pictures Slideshow: 14 Non-Drug Treatments for Migraines
Source: MedicineNet Headache Specialty [2015.06.26]
Title: Migraine Headaches Pictures Slideshow: 14 Non-Drug Treatments for Migraines
Category: Slideshows
Created: 6/25/2012 12:00:00 AM
Last Editorial Review: 6/26/2015 12:00:00 AM

Pediatric Primary Headache From A to Z
Source: Medscape Emergency Medicine Headlines [2015.06.24]
A special symposium at this year's PAS addressed pediatric headache and migraine, emphasizing the need to approach them as functional problems.
Medscape Pediatrics

Consensus Criteria for Refractory Chronic Cluster Headache
Source: Medscape NeurologyHeadlines [2015.06.23]
The European Headache Federation has developed a consensus statement on what constitutes refractory chronic cluster headache.
Medscape Medical News

NeuroBreak: Opioid Overload in Headache, A-Beta Still Drawing Big Bucks
Source: MedPage Today Neurology [2015.06.23]
(MedPage Today) -- News and commentary from the world of neurology and neuroscience

Tension Headache
Source: MedicineNet Cauliflower Ear Specialty [2015.06.22]
Title: Tension Headache
Category: Diseases and Conditions
Created: 2/4/2005 12:00:00 AM
Last Editorial Review: 6/22/2015 12:00:00 AM

more news >>

Published Studies Related to Phrenilin (Butalbital / Acetaminophen)

Sumatriptan-Naproxen and Butalbital: A Double-Blind, Placebo-Controlled Crossover Study. [2011.11.21]
Objectives.- The primary objective was to compare the efficacy of a sumatriptan and naproxen combination medication (SumaRT/Nap-85 mg sumatriptan and 500 mg naproxen sodium), a butalbital-containing combination medication (BCM-50 mg butalbital, 325 mg acetaminophen, 40 mg caffeine), and placebo when used to treat moderate to severe migraine headache pain in subjects who used BCMs in the past.

Butalbital in the treatment of headache: history, pharmacology, and efficacy. [2001.11]
Analgesics containing butalbital compounded with aspirin, acetaminophen, and/or caffeine are widely used for the treatment of migraine and tension-type headache. The butalbital-containing compounds are efficacious in placebo-controlled trials among patients with episodic tension-type headaches.Because of concerns about overuse, medication-overuse headache, and withdrawal, their use should be limited and carefully monitored.

more studies >>

Page last updated: 2015-06-26

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