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Phrenilin (Butalbital / Acetaminophen) - Summary



PHRENILIN®: Each PHRENILIN® tablet for oral administration, contains Butalbital, USP 50 mg, Acetaminophen, USP 325 mg.

PHRENILIN® tablets and PHRENILIN® FORTE capsules are indicated for the relief of the symptom complex of tension (or muscle contraction) headache.

Evidence supporting the efficacy and safety of this combination product in the treatment of multiple recurrent headaches is unavailable. Caution in this regard is required because butalbital is habitforming and potentially abusable.

See all Phrenilin indications & dosage >>


Media Articles Related to Phrenilin (Butalbital / Acetaminophen)

Health Tip: What May Trigger Tension Headaches
Source: MedicineNet Headache Specialty [2014.04.11]
Title: Health Tip: What May Trigger Tension Headaches
Category: Health News
Created: 4/11/2014 7:35:00 AM
Last Editorial Review: 4/11/2014 12:00:00 AM

Dizziness and headache can be symptoms of stroke, especially in women, minorities and younger patients
Source: Headache / Migraine News From Medical News Today [2014.04.08]
Doctors overlook or discount the early signs of potentially disabling strokes in tens of thousands of American women each year, a large number of them visitors to emergency rooms complaining of...

More ERs Treating Headaches With Narcotics, Study Finds
Source: MedicineNet acetaminophen Specialty [2014.04.03]
Title: More ERs Treating Headaches With Narcotics, Study Finds
Category: Health News
Created: 4/2/2014 5:36:00 PM
Last Editorial Review: 4/3/2014 12:00:00 AM

$1 billion a year is spent on brain scans for headache sufferers
Source: Headache / Migraine News From Medical News Today [2014.03.18]
Contrary to guidelines, 12% of patients going to their doctor with headache are given brain scans. A new study in JAMA Internal Medicine warns of the substantial health care costs.

Study finds high utilization of neuroimaging for headaches despite guidelines
Source: Headache / Migraine News From Medical News Today [2014.03.18]
Neuroimaging for headaches is frequently ordered by physicians during outpatient visits, despite guidelines that recommend against such routine procedures.

more news >>

Published Studies Related to Phrenilin (Butalbital / Acetaminophen)

Sumatriptan-Naproxen and Butalbital: A Double-Blind, Placebo-Controlled Crossover Study. [2011.11.21]
Objectives.- The primary objective was to compare the efficacy of a sumatriptan and naproxen combination medication (SumaRT/Nap-85 mg sumatriptan and 500 mg naproxen sodium), a butalbital-containing combination medication (BCM-50 mg butalbital, 325 mg acetaminophen, 40 mg caffeine), and placebo when used to treat moderate to severe migraine headache pain in subjects who used BCMs in the past.

Butalbital in the treatment of headache: history, pharmacology, and efficacy. [2001.11]
Analgesics containing butalbital compounded with aspirin, acetaminophen, and/or caffeine are widely used for the treatment of migraine and tension-type headache. The butalbital-containing compounds are efficacious in placebo-controlled trials among patients with episodic tension-type headaches.Because of concerns about overuse, medication-overuse headache, and withdrawal, their use should be limited and carefully monitored.

more studies >>

Page last updated: 2014-04-11

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