Phendimetrazine tartrate is a phenylalkylamine sympathomimetic
amine with pharmacological activity similar to the prototype drugs of this class
used in obesity, the amphetamines.
Phendimetrazine tartrate tablets are indicated in the management of exogenous
obesity as a short term adjunct (a few weeks) in a regimen of weight reduction
based on caloric restriction. The limited usefulness of agents of this class
PHARMACOLOGY) should be measured against possible risk factors
inherent in their use such as those described below.
Media Articles Related to Phendimetrazine
Morning Report: New T2DM Guideline, Metformin, New Term for Obesity
Source: Medscape Family Medicine Headlines [2017.01.13]
Dr Arefa Cassoobhoy highlights some of this week's most important medical news, including new ACP guidelines for type 2 diabetes, expanded use of metformin, and adiposity-based chronic disease.
Medscape Internal Medicine
No silver bullet to beating obesity, study finds
Source: Nutrition / Diet News From Medical News Today [2017.01.12]
As many seek to battle festive bulge in January, new research challenges previous findings that any single aspect of diet or lifestyle can be targeted to reduce the risk of obesity in adults with a...
Obesity-associated protein could be linked to leukemia development
Source: Biology / Biochemistry News From Medical News Today [2016.12.30]
Cancer researchers at the University of Cincinnati (UC) College of Medicine have found an obesity-associated protein's role in leukemia development and drug response which could lead to more...
Children with higher genetic risk for obesity respond more strongly to fast food ads
Source: Obesity / Weight Loss / Fitness News From Medical News Today [2016.12.23]
Dartmouth researchers have found that children with a genetic risk for obesity had greater activity in brain reward centers when watching fast food commercials, which could help us to understand...
Sleep disruption has genetic links with obesity, schizophrenia
Source: Obesity / Weight Loss / Fitness News From Medical News Today [2016.12.20]
Genome analysis of over 112,500 participants in the UK Biobank links self-reported sleep disruption to obesity, restless legs syndrome, and schizophrenia.
Clinical Trials Related to Phendimetrazine
Reinforcing Effects of Cocaine During Phendimetrazine Maintenance [Recruiting]
This study will determine the initial efficacy of phendimetrazine as a pharmacotherapy for
cocaine dependence. A rigorous, inpatient human laboratory study will be conducted in which
the subjective, physiological and reinforcing effects of cocaine are evaluated during
maintenance on placebo and phendimetrazine.
Phendimetrazine and Cocaine [Recruiting]
This study will determine the safety and tolerability of phendimetrazine (Bontril®) as a
pharmacotherapy for cocaine use disorder. A rigorous, inpatient human laboratory study will
be conducted in which the subjective and physiological effects of cocaine are evaluated
during maintenance on placebo and phendimetrazine.
Stemcells for Radiation Induced Xerostomia [Enrolling by invitation]
The current study aims to assess the safety and feasibility of the injection of autologous
adipost tissue derived MSCs on radiation-induced salivary gland hypofunction and xerostomia
in head and neck cancer participants. The project can potentially help to develop a
clinically relevant treatment option for the growing number of patients suffering from
xerostomia after radiotherapy. The development of new therapies is especially important,
since only sub-optimal symptomatic treatments are currently available and the symptom of
xerostomia greatly reduces the quality of life.
Efficacy of Natural Vitamin E Tocotrienol on the Treatment of Surgical Scars [Recruiting]
The overall goal of this study is to determine the efficacy of tocotrienol (TCT), a natural
form of vitamin E, in preventing or reducing scar formation in human skin wounds as well as
the basal levels of TCT in normal human skin and adipose tissue.
PATIENT REVIEWS / RATINGS / COMMENTS
Based on a total of 1 ratings/reviews, Phendimetrazine has an overall score of 10. The effectiveness score is 10 and the side effect score is 4. The scores are on ten point scale: 10 - best, 1 - worst.
Phendimetrazine review by 27 year old male patient
|Overall rating:|| || |
|Effectiveness:|| || Highly Effective|
|Side effects:|| || Severe Side Effects|
|Condition / reason:|| || weight loss|
|Dosage & duration:|| || 35mg taken 2 times per day for the period of 4 weeks|
|Other conditions:|| || none|
|Other drugs taken:|| || none|
|Benefits:|| || A total of 20 pounds lost in one month. |
|Side effects:|| || Although I reached my goal weight, the drug made me very restless, anxious, moody. I also experienced headaches, and falling asleep was not easy while on this drug. Dizziness, light headed.|
|Comments:|| || Take one 35mg pill in the morning and one after lunch to curb appetite. I fond myself able to stay more active and run longer at the gym. It's a toss up if the results were worth the side effects. It's obvious that a drug this strong that makes you want to run a marathon and not eat can't be good for you!|
Page last updated: 2017-01-13