Phendimetrazine tartrate is a phenylalkylamine sympathomimetic
amine with pharmacological activity similar to the prototype drugs of this class
used in obesity, the amphetamines.
Phendimetrazine tartrate tablets are indicated in the management of exogenous
obesity as a short term adjunct (a few weeks) in a regimen of weight reduction
based on caloric restriction. The limited usefulness of agents of this class
PHARMACOLOGY) should be measured against possible risk factors
inherent in their use such as those described below.
Media Articles Related to Phendimetrazine
Unsaturated fatty acid may reverse aging effect of obesity
Source: Immune System / Vaccines News From Medical News Today [2017.02.17]
Obesity, or a high fat diet, can lead to changes in the immune system similar to those observed with aging. That's what research published in Experimental Physiology suggests.
Worm gene could be key to developing obesity treatment
Source: Genetics News From Medical News Today [2017.02.15]
Monash University and Danish researchers have discovered a gene in worms that could help break the cycle of overeating and under-exercising that can lead to obesity.
FDA Issues Warning About Balloon Obesity Treatments
Source: MedicineNet Obesity (Weight Loss) Specialty [2017.02.14]
Title: FDA Issues Warning About Balloon Obesity Treatments
Category: Health News
Created: 2/13/2017 12:00:00 AM
Last Editorial Review: 2/14/2017 12:00:00 AM
Air Pollution 'a Catalyst' for Obesity, Diabetes in Children
Source: Medscape Allergy & Clinical Immunology Headlines [2017.02.13]
"Poor air quality appears to be a catalyst for obesity and diabetes in children," conclude authors of a study finding a role for exposure to air pollution in the etiology of type 2 diabetes in youth.
Medscape Medical News
Obesity may raise heart risk by triggering harmful immune response
Source: Cardiovascular / Cardiology News From Medical News Today [2017.02.13]
New research suggests that obesity caused by a high-fat diet increases immune system T cells, resulting in inflammation that raises cardiovascular risk.
Clinical Trials Related to Phendimetrazine
Reinforcing Effects of Cocaine During Phendimetrazine Maintenance [Recruiting]
This study will determine the initial efficacy of phendimetrazine as a pharmacotherapy for
cocaine dependence. A rigorous, inpatient human laboratory study will be conducted in which
the subjective, physiological and reinforcing effects of cocaine are evaluated during
maintenance on placebo and phendimetrazine.
Phendimetrazine and Cocaine [Recruiting]
This study will determine the safety and tolerability of phendimetrazine (Bontril®) as a
pharmacotherapy for cocaine use disorder. A rigorous, inpatient human laboratory study will
be conducted in which the subjective and physiological effects of cocaine are evaluated
during maintenance on placebo and phendimetrazine.
Stemcells for Radiation Induced Xerostomia [Enrolling by invitation]
The current study aims to assess the safety and feasibility of the injection of autologous
adipost tissue derived MSCs on radiation-induced salivary gland hypofunction and xerostomia
in head and neck cancer participants. The project can potentially help to develop a
clinically relevant treatment option for the growing number of patients suffering from
xerostomia after radiotherapy. The development of new therapies is especially important,
since only sub-optimal symptomatic treatments are currently available and the symptom of
xerostomia greatly reduces the quality of life.
Efficacy of Natural Vitamin E Tocotrienol on the Treatment of Surgical Scars [Recruiting]
The overall goal of this study is to determine the efficacy of tocotrienol (TCT), a natural
form of vitamin E, in preventing or reducing scar formation in human skin wounds as well as
the basal levels of TCT in normal human skin and adipose tissue.
PATIENT REVIEWS / RATINGS / COMMENTS
Based on a total of 1 ratings/reviews, Phendimetrazine has an overall score of 10. The effectiveness score is 10 and the side effect score is 4. The scores are on ten point scale: 10 - best, 1 - worst.
Phendimetrazine review by 27 year old male patient
|Overall rating:|| || |
|Effectiveness:|| || Highly Effective|
|Side effects:|| || Severe Side Effects|
|Condition / reason:|| || weight loss|
|Dosage & duration:|| || 35mg taken 2 times per day for the period of 4 weeks|
|Other conditions:|| || none|
|Other drugs taken:|| || none|
|Benefits:|| || A total of 20 pounds lost in one month. |
|Side effects:|| || Although I reached my goal weight, the drug made me very restless, anxious, moody. I also experienced headaches, and falling asleep was not easy while on this drug. Dizziness, light headed.|
|Comments:|| || Take one 35mg pill in the morning and one after lunch to curb appetite. I fond myself able to stay more active and run longer at the gym. It's a toss up if the results were worth the side effects. It's obvious that a drug this strong that makes you want to run a marathon and not eat can't be good for you!|