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Phendimetrazine (Phendimetrazine Tartrate) - Summary

 
 



SUMMARY

Phendimetrazine tartrate is a phenylalkylamine sympathomimetic amine with pharmacological activity similar to the prototype drugs of this class used in obesity, the amphetamines.

Phendimetrazine tartrate tablets are indicated in the management of exogenous obesity as a short term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction. The limited usefulness of agents of this class (see CLINICAL PHARMACOLOGY) should be measured against possible risk factors inherent in their use such as those described below.


See all Phendimetrazine indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Phendimetrazine

Distal vs Standard Gastric Bypass in Severe Obesity
Source: Medscape General Surgery Headlines [2016.09.23]
For patients with an extremely high BMI, distal Roux-en-Y gastric bypass is no more effective than the standard procedure, and is associated with serious adverse effects, researchers in Norway report.
Reuters Health Information

Childhood Obesity May Impact Risk for Adult Knee OA (CME/CE)
Source: MedPageToday.com - medical news plus CME for physicians [2016.09.23]
(MedPage Today) -- Review highlights need to control for risk factors early in life

Obesity Gene Shows No Effect on Weight Loss, Review Suggests
Source: Medscape Diabetes & Endocrinology Headlines [2016.09.21]
People with the FTO obesity gene respond to weight-loss treatments as well as the rest of the population; an expert emphasizes the importance of environmental factors over genes in weight loss.
Medscape Medical News

Medical News Today: Gut bacteria may affect obesity risk in youth
Source: Featured Health News from Medical News Today [2016.09.21]
Children and adolescents who are obese have different populations of gut microbes compared with youths of a normal weight, new research finds.

'Obesity gene' does not hinder weight loss
Source: Genetics News From Medical News Today [2016.09.21]
The belief that so-called obesity genes can hinder weight loss is called into question by a new study review. Genetics may not be so vital after all.

more news >>

Clinical Trials Related to Phendimetrazine

Reinforcing Effects of Cocaine During Phendimetrazine Maintenance [Recruiting]
This study will determine the initial efficacy of phendimetrazine as a pharmacotherapy for cocaine dependence. A rigorous, inpatient human laboratory study will be conducted in which the subjective, physiological and reinforcing effects of cocaine are evaluated during maintenance on placebo and phendimetrazine.

Phendimetrazine and Cocaine [Recruiting]
This study will determine the safety and tolerability of phendimetrazine (Bontril®) as a pharmacotherapy for cocaine use disorder. A rigorous, inpatient human laboratory study will be conducted in which the subjective and physiological effects of cocaine are evaluated during maintenance on placebo and phendimetrazine.

Stemcells for Radiation Induced Xerostomia [Enrolling by invitation]
The current study aims to assess the safety and feasibility of the injection of autologous adipost tissue derived MSCs on radiation-induced salivary gland hypofunction and xerostomia in head and neck cancer participants. The project can potentially help to develop a clinically relevant treatment option for the growing number of patients suffering from xerostomia after radiotherapy. The development of new therapies is especially important, since only sub-optimal symptomatic treatments are currently available and the symptom of xerostomia greatly reduces the quality of life.

Efficacy of Natural Vitamin E Tocotrienol on the Treatment of Surgical Scars [Recruiting]
The overall goal of this study is to determine the efficacy of tocotrienol (TCT), a natural form of vitamin E, in preventing or reducing scar formation in human skin wounds as well as the basal levels of TCT in normal human skin and adipose tissue.

more trials >>


PATIENT REVIEWS / RATINGS / COMMENTS

Based on a total of 1 ratings/reviews, Phendimetrazine has an overall score of 10. The effectiveness score is 10 and the side effect score is 4. The scores are on ten point scale: 10 - best, 1 - worst.
 

Phendimetrazine review by 27 year old male patient

  Rating
Overall rating:  
Effectiveness:   Highly Effective
Side effects:   Severe Side Effects
  
Treatment Info
Condition / reason:   weight loss
Dosage & duration:   35mg taken 2 times per day for the period of 4 weeks
Other conditions:   none
Other drugs taken:   none
  
Reported Results
Benefits:   A total of 20 pounds lost in one month.
Side effects:   Although I reached my goal weight, the drug made me very restless, anxious, moody. I also experienced headaches, and falling asleep was not easy while on this drug. Dizziness, light headed.
Comments:   Take one 35mg pill in the morning and one after lunch to curb appetite. I fond myself able to stay more active and run longer at the gym. It's a toss up if the results were worth the side effects. It's obvious that a drug this strong that makes you want to run a marathon and not eat can't be good for you!

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Page last updated: 2016-09-23

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