Periostat Related Published Studies
Well-designed clinical trials related to Periostat (Doxycycline Hyclate)
Effect of doxycycline vs placebo on retinal function and diabetic retinopathy
progression in mild to moderate nonproliferative diabetic retinopathy: a
randomized proof-of-concept clinical trial. [2014]
The effect of prolonged systemic doxycycline therapy on serum tissue degrading
proteinases in coronary bypass patients: a randomized, double-masked,
placebo-controlled clinical trial. [2014]
Subantimicrobial-dose doxycycline treatment increases serum cholesterol efflux
capacity from macrophages. [2013]
A study of the clinical activity of a gel combining monocaprin and doxycycline: a
novel treatment for herpes labialis. [2012]
Clinical studies on the management of periodontal diseases utilizing subantimicrobial dose doxycycline (SDD). [2011.02]
Comparative evaluation of the efficacy of 10% doxycycline hyclate in the periodontal treatment of smokers - a clinical and microbiological study. [2011]
Sub-antimicrobial doxycycline for periodontitis reduces hemoglobin A1c in
subjects with type 2 diabetes: a pilot study. [2011]
Pulsed azithromycin treatment is as effective and safe as 2-week-longer daily
doxycycline treatment of acne vulgaris: a randomized, double-blind,
noninferiority study. [2011]
The effect of subantimicrobial-dose-doxycycline periodontal therapy on serum
biomarkers of systemic inflammation: a randomized, double-masked,
placebo-controlled clinical trial. [2011]
Comparison of therapeutic effects of oral doxycycline and azithromycin in
patients with moderate acne vulgaris: What is the role of age? [2011]
Effective and safe combination therapy for severe acne vulgaris: a randomized, vehicle-controlled, double-blind study of adapalene 0.1%-benzoyl peroxide 2.5% fixed-dose combination gel with doxycycline hyclate 100 mg. [2010.02]
A single dose of doxycycline in combination with diethylcarbamazine for treatment
of bancroftian filariasis. [2010]
Doxycycline vs. levofloxacin in the treatment of community-acquired pneumonia. [2010]
Oral steroids and doxycycline: two different approaches to treat nasal polyps. [2010]
Doxycycline 40 mg capsules (30 mg immediate-release/10 mg delayed-release beads): anti-inflammatory dose in rosacea. [2010]
Doxycycline effects on serum bone biomarkers in post-menopausal women. [2010]
Administration of doxycycline in drinking water for treatment of spiral bacterial infection in cockatiels. [2008.02.01]
Regeneration of degree ii furcation defects with a 4% doxycycline hyclate bioabsorbable barrier. [2008.01]
A randomized-controlled trial of low-dose doxycycline for periodontitis in smokers. [2007.04]
Pharmacokinetic and bioequivalence study of meloxicam tablets in healthy male subjects. [2007]
The effect of topical doxycycline usage on gingival crevicular fluid MMP-8 levels of chronic and aggressive periodontitis patients: a pilot study. [2006.08]
A randomized, double-blind, placebo-controlled trial of the combined effect of doxycycline hyclate 20-mg tablets and metronidazole 0.75% topical lotion in the treatment of rosacea. [2005.11]
Effect of locally delivered doxycycline hyclate on human fibroblast attachment to subgingival calculus. [2005.02]
The treatment of acne vulgaris with low dosage doxycycline. [2005]
Effect of subantimicrobial dose doxycycline as an effective adjunct to scaling and root planing. [2004.11]
Sustained release of doxycycline for the treatment of peri-implantitis: randomised controlled trial. [2004.10]
Initial antimicrobial effect of controlled-release doxycycline in subgingival sites. [2004.10]
Therapy with adjunctive doxycycline local delivery in patients with type 1 diabetes mellitus and periodontitis. [2004.08]
Comparative bioavailability study of doxycycline hyclate (equivalent to 100 mg doxycycline) capsules (doxycin vs vibramycin) for bioequivalence evaluation in healthy adult volunteers. [2004.07]
Comparison of the pharmacokinetic profiles of two locally administered doxycycline gels in crevicular fluid and saliva. [2004.04]
Effects of subantimicrobial-dose doxycycline in the treatment of moderate acne. [2003.04]
Tolerability of doxycycline monohydrate salt vs. chloroquine-proguanil in malaria chemoprophylaxis. [2002.11]
Utilisation of locally delivered doxycycline in non-surgical treatment of chronic periodontitis. A comparative multi-centre trial of 2 treatment approaches. [2001.08]
The effect of locally delivered controlled-release doxycycline or scaling and root planing on periodontal maintenance patients over 9 months. [2000.01]
Effects of smoking on local delivery of controlled-release doxycycline as compared to scaling and root planing. [1999.10]
Two multi-center studies evaluating locally delivered doxycycline hyclate, placebo control, oral hygiene, and scaling and root planing in the treatment of periodontitis. [1999.05]
Long-term sub-antimicrobial doxycycline (Periostat) as adjunctive management in adult periodontitis: effects on subgingival bacterial population dynamics. [1998.11]
The pharmacokinetic profile of a biodegradable controlled-release delivery system containing doxycycline compared to systemically delivered doxycycline in gingival crevicular fluid, saliva, and serum. [1998.10]
Doxycycline hyclate treatment of experimental canine ehrlichiosis followed by challenge inoculation with two Ehrlichia canis strains. [1998.02]
Multi-center comparative evaluation of subgingivally delivered sanguinarine and doxycycline in the treatment of periodontitis. II. Clinical results. [1997.02]
Randomized comparison of ofloxacin and doxycycline for chlamydia and ureaplasma urethritis and cervicitis. [1990]
Effect of oral antacid administration on the pharmacokinetics of intravenous doxycycline. [1989.04]
Well-designed clinical trials possibly related to Periostat (Doxycycline Hyclate)
Preventive study in subjects at risk of fatal familial insomnia: Innovative
approach to rare diseases. [2015]
Effects of centrally acting angiotensin converting enzyme inhibitors on
functional decline in patients with Alzheimer's disease. [2014]
The association between clinical and radiographic periodontitis measurements
during periodontal maintenance. [2013]
Safety and efficacy of WC2031 versus vibramycin for the treatment of
uncomplicated urogenital Chlamydia trachomatis infection: a randomized,
double-blind, double-dummy, active-controlled, multicenter trial. [2012]
Short-term combination therapy and long-term relapse prevention in the treatment
of severe acne vulgaris. [2012]
Serum bone biomarkers and oral/systemic bone loss in humans. [2011]
Antibiotics in addition to systemic corticosteroids for acute exacerbations of
chronic obstructive pulmonary disease. [2010]
Systemic MMP inhibition for periodontal wound repair: results of a multi-centre randomized-controlled clinical trial. [2009.02]
Combining host modulation and topical antimicrobial therapy in the management of moderate to severe periodontitis: a randomized multicenter trial. [2008.01]
Reduction in antimicrobial substantivity of MTAD after initial sodium hypochlorite irrigation. [2006.10]
Clinical experience results with clindamycin 1% benzoyl peroxide 5% gel (Duac) as monotherapy and in combination. [2005.03]
Local antimicrobial therapy after initial periodontal treatment. [2002.06]
The effect of postsurgical antibiotics and a bioabsorbable membrane on regenerative healing in Class II furcation defects. [1999.08]
Clinical evaluation of the use of calcium sulfate in regenerative periodontal surgery for the treatment of Class III furcation involvement. [1999]
Other research related to Periostat (Doxycycline Hyclate)
The efficacy of artesunate, chloroquine, doxycycline, primaquine and a
combination of artesunate and primaquine against avian malaria in broilers. [2014]
A 2-year randomised placebo-controlled trial of doxycycline for
lymphangioleiomyomatosis. [2014]
Evaluation of single-dose azithromycin versus standard azithromycin/doxycycline
treatment and clinical assessment of regression course in patients with adult
inclusion conjunctivitis. [2013]
Single application of topical doxycycline hyclate in the management of recurrent
aphthous stomatitis. [2013]
Doxycycline reduces cardiac matrix metalloproteinase-2 activity but does not
ameliorate myocardial dysfunction during reperfusion in coronary artery bypass
patients undergoing cardiopulmonary bypass. [2013]
The effect of sub-antimicrobial dose-doxycycline periodontal therapy on serum
inflammatory biomarker C-reactive protein levels in post-menopausal Women: A
2-year, double-blinded, randomized clinical trial. [2013]
Experimental determination of a subantimicrobial dosage of doxycycline hyclate
for treatment of periodontitis in Beagles. [2013]
Randomized masked controlled clinical trial to compare 7-day and 14-day course
length of doxycycline in the treatment of Mycoplasma felis infection in shelter
cats. [2013]
A double-blind controlled field trial of doxycycline and albendazole in
combination for the treatment of bancroftian filariasis in India. [2013]
Comparison of the efficacy of amoxicillin-clavulanic acid, cefovecin, and
doxycycline in the treatment of upper respiratory tract disease in cats housed in
an animal shelter. [2012]
Doxycycline in the treatment of bleeding with DMPA: a double-blinded randomized
controlled trial. [2012]
Comparison of doxycycline-streptomycin, doxycycline-rifampin, and
ofloxacin-rifampin in the treatment of brucellosis: a randomized clinical trial. [2012]
Effects of combination therapy with celecoxib and doxycycline on neointimal
hyperplasia and inflammatory biomarkers in coronary artery disease patients
treated with bare metal stents. [2012]
Matrix metalloproteinase activity in stifle synovial fluid of cranial cruciate
ligament deficient dogs and effect of postoperative doxycycline treatment. [2012]
A randomized controlled trial of subantimicrobial-dose doxycycline to prevent
unscheduled bleeding with continuous oral contraceptive pill use. [2012]
A randomized study comparing levofloxacin, omeprazole, nitazoxanide, and
doxycycline versus triple therapy for the eradication of Helicobacter pylori. [2011]
Biowaiver monographs for immediate release solid oral dosage forms: Doxycycline hyclate. [2010.04]
Doxycycline-mediated inhibition of matrix metalloproteinases improves healing after rotator cuff repair. [2010.02]
Comparative evaluation of subgingivally delivered 10% doxycycline hyclate and xanthan-based chlorhexidine gels in the treatment of chronic periodontitis. [2008.11.01]
The use and safety of doxycycline hyclate and other second-generation tetracyclines. [2008.09]
Pharmacokinetics after administration of an injectable experimental long-acting parenteral formulation of doxycycline hyclate in goats. [2008.08]
Pharmacokinetic study of an injectable long-acting parenteral formulation of doxycycline hyclate in calves. [2008.06]
A doxycycline hyclate rodent bait formulation for prophylaxis and treatment of tick-transmitted Borrelia burgdorferi. [2008.05]
A sustained-release formulation of doxycycline hyclate (Atridox) prevents simultaneous infection of Anaplasma phagocytophilum and Borrelia burgdorferi transmitted by tick bite. [2008.04]
Pharmacokinetics of doxycycline and tissue concentrations of an experimental long-acting parenteral formulation of doxycycline in Wistar rats. [2008]
Antibacterial activity and drug release of chitosan sponge containing doxycycline hyclate. [2008]
Intra-articular administration of doxycycline in calves. [2007.12]
Tick acquisition of Ehrlichia canis from dogs treated with doxycycline hyclate. [2007.09]
The use of doxycycline in periodontology. Histologic in vivo study on mice affected by diabetes mellitus. [2006.01]
Assessment of salivary levels of the chosen exoglycosidases in patients with aggressive periodontitis after treatment with doxycycline. [2006]
Sustained-release formulation of doxycycline hyclate for prophylaxis of tick bite infection in a murine model of Lyme borreliosis. [2004.07]
Assessment of plasma concentrations of doxycycline in budgerigars fed medicated seed or water. [2003.10.01]
Subantimicrobial dose doxycycline for acne and rosacea. [2003.07]
The effects of subgingival calculus on the clinical outcomes of locally-delivered controlled-release doxycycline compared to scaling and root planing. [2002.02]
The significance of prior mechanical therapy for changes of periodontal status achieved by local delivery of a doxycyclinehyclate containing gel. [2001.12]
The role of Periostat in the management of adult periodontitis: a critical assessment. [1999.07]
Evaluation of Periostat for patient management. [1999.05]
Locally delivered doxycycline hyclate: case selection, preparation, and application. [1999]
The use of locally delivered doxycycline in the treatment of periodontitis. Clinical results. [1998.11]
Periodontal pocket treatment in beagle dogs using subgingival doxycycline from a biodegradable system. I. Initial clinical responses. [1996.11]
Histologic changes of doxycycline pleurodesis in rabbits. Effect of concentration and pH. [1994.10]
Effect of doxycycline hyclate on corneal epithelial wound healing in the rabbit alkali-burn model. Preliminary observations. [1993.09]
Pharmacokinetics and bioavailability of doxycycline hyclate after oral administration in calves. [1993.03]
Comparative pharmacokinetics of doxycycline in cats and dogs. [1990.12]
Pharmacokinetics and metabolic inertness of doxycycline in young pigs. [1990.08]
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