Pentazocine hydrochloride and acetaminophen tablets are a combination of pentazocine hydrochloride USP, equivalent to 25 mg base and acetaminophen USP, 650 mg. Pentazocine is a member of the benzazocine series (also known as the benzomorphan series).
Pentazocine hydrochloride and acetaminophen tablets are indicated for the relief of mild to moderate pain.
Media Articles Related to Pentazocine and Acetaminophen (Pentazocine / Acetaminophen)
Tackling inflammatory pain
Source: Immune System / Vaccines News From Medical News Today [2014.08.29]
Pain from inflammation sidelines thousands of Americans each year. Many face a tough choice: deal with the pain, take a potentially addictive opioid or use a nonsteroidal anti-inflammatory drug that...
'Doctor-Shopping' for Painkillers Common After Broken-Bone Surgery, Study Finds
Source: MedicineNet Chronic Pain Specialty [2014.08.29]
Title: 'Doctor-Shopping' for Painkillers Common After Broken-Bone Surgery, Study Finds
Category: Health News
Created: 8/29/2014 9:35:00 AM
Last Editorial Review: 8/29/2014 12:00:00 AM
Iroko Pharmaceuticals gains FDA approval of ZORVOLEX® for management of osteoarthritis pain
Source: Arthritis / Rheumatology News From Medical News Today [2014.08.28]
Iroko Pharmaceuticals, LLC, a global specialty pharmaceutical company dedicated to advancing the science of analgesia, has announced the United States Food and Drug Administration (FDA) has...
States that legalize medical marijuana 'have fewer deaths from opioid painkillers'
Source: Alcohol / Addiction / Illegal Drugs News From Medical News Today [2014.08.26]
Annual deaths from prescription painkillers are, on average, 25% lower in states that legalize medical marijuana, according to a new study from Johns Hopkins researchers.
The effect of serotonin on sensitivity to pain
Source: Depression News From Medical News Today [2014.08.26]
In a study published in the scientific journal PLoS One, researchers at the Champalimaud Neuroscience Programme establish the effect of serotonin on sensitivity to pain using a combination of...
Published Studies Related to Pentazocine and Acetaminophen (Pentazocine / Acetaminophen)
[Postoperative nausea and vomiting after laparoscopic cholecystectomy under total intravenous anesthesia using propofol combined with fentanyl or pentazocine] [2007.11]
BACKGROUND: The aim of this study was to compare the incidence of postoperative nausea and vomiting (PONV) in propofol-anesthetized patients receiving either fentanyl or pentazocine as opioid supplement... CONCLUSIONS: The incidence of PONV in propofol-anesthetized patients receiving pentazocine as opioid supplement is not different from that in patients receiving fentanyl.
Clinical Trials Related to Pentazocine and Acetaminophen (Pentazocine / Acetaminophen)
Effects of Pentazocine Versus Lorazepam or Placebo on Manic Symptoms [Recruiting]
Pilot data indicates that pentazocine decreases manic symptoms in hospitalized individuals.
To follow up these initial findings, we plan to conduct a larger, more rigorous,
double-blind study. We will examine whether pentazocine, an agent with kappa-opiate
activity, decreases manic symptoms.
Effects of Pentazocine on Manic Symptoms [Active, not recruiting]
The opiate neurotransmitter system is thought to be involved in many abnormal mood states.
Some researchers have suggested that changes in this system may trigger the switch to/from
manic and depressive states in bipolar disorder. One problem with most of the currently
available opiate medications is that they can produce addiction/dependence. A particular
kind of opiate medication known as kappa-opiates may be able to produce changes in this
system with much less risk of addiction. This study looks at Talwin (a combination of
pentazocine and naloxone), a medication which affects the kappa and mu opiate systems. The
study will examine whether two doses of Talwin affect manic symptoms in people who have been
admitted to the hospital. This study will give more information about the involvement of the
opiate system in bipolar disorder, and give important information for use in developing new