PCE (Erythromycin Base Particles) - Side Effects and Adverse Reactions

ADVERSE REACTIONS

The most frequent side effects of oral erythromycin preparations are gastrointestinal and are dose-related. They include nausea, vomiting, abdominal pain, diarrhea and anorexia. Symptoms of hepatitis, hepatic dysfunction and/or abnormal liver function test results may occur. (See WARNINGS.)

Onset of pseudomembranous colitis symptoms may occur during or after antibacterial treatment. (See WARNINGS.)

Erythromycin has been associated with QT prolongation and ventricular arrhythmias, including ventricular tachycardia and torsades de pointes. (See WARNINGS.)

Allergic reactions ranging from urticaria to anaphylaxis have occurred. Skin reactions ranging from mild eruptions to erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis have been reported rarely.

There have been reports of interstitial nephritis coincident with erythromycin use.

There have been rare reports of pancreatitis and convulsions.

There have been isolated reports of reversible hearing loss occurring chiefly in patients with renal insufficiency and in patients receiving high doses of erythromycin.

REPORTS OF SUSPECTED PCE SIDE EFFECTS / ADVERSE REACTIONS

Possible PCE side effects / adverse reactions in 62 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-18

Patient: 62 year old female weighing 83.9 kg (184.6 pounds)

Reactions: Abdominal Pain Lower, Abdominal Pain, Osteoporosis, Peripheral Vascular Disorder, Musculoskeletal Discomfort, Osteopenia, Fall, Arthropathy, Limb Discomfort, Neck Pain, Chest Pain, Hypothyroidism, Depression, Bone Density Decreased, Influenza

Suspect drug(s):
Nexium
    Dosage: 1/day, took 2/day from february 2006 to december 2006
    Administration route: Oral
    Start date: 2001-04-01

PCE

Uromar
    Indication: Bladder Spasm

Nexium
    Dosage: 1/day, took 2/day from february 2006 to december 2006
    Administration route: Oral
    Start date: 2001-04-01

Nexium
    Administration route: Oral
    Start date: 2001-12-18

Cefzil

Nexium
    Administration route: Oral
    Indication: Gastrooesophageal Reflux Disease
    Start date: 2001-01-01

Nexium
    Administration route: Oral
    Indication: Chest Pain
    Start date: 2001-01-01

Nexium
    Administration route: Oral

Phenergan

Nexium
    Administration route: Oral

Bentyl

Metamucil-2

Nexium
    Administration route: Oral
    Start date: 2001-12-18

Other drugs received by patient: Prilosec; Premarin; Paxil; Prilosec; Prilosec; Nitroglycerin; Prilosec; Prilosec; Plavix; Norvasc; Diovan; Fosamox; Prilosec; Levothyroxine Sodium; Effexor XR; Hydrochlorothizide; Zocor; Plavix; Celexa; Cenestin; Paxil; Effexor XR; Atenolol; Avapro; Celexa; Aspirin; Citalopram Hydrobromide