Pamine® 2.5 mg/Pamine® Forte 5 mg Tablets
Pamine® 2.5 mg/Pamine® Forte 5 mg Tablets contain methscopolamine bromide, an anticholinergic agent.
Pamine (methscopolamine cation) is indicated for the following:
Adjunctive therapy for the treatment of peptic ulcer.
METHSCOPOLAMINE BROMIDE HAS NOT BEEN SHOWN TO BE EFFECTIVE IN CONTRIBUTING TO THE HEALING OF PEPTIC ULCER, DECREASING THE RATE OF RECURRENCE OR PREVENTING COMPLICATIONS.
Media Articles Related to Pamine (Methscopolamine)
In Parkinson's disease, Chinese medicines that tonify the kidney inhibit dopaminergic neuron apoptosis
Source: Urology / Nephrology News From Medical News Today [2013.12.02]
Parkinson's disease is a common neurodegenerative disease in the elderly, which is pathologically characterized by selective loss of dopaminergic neurons. Compound preparations of Chinese medicines that can tonify the kidney have been reported to significantly improve symptoms of Parkinson's disease. However, the mechanism of action remains unclear.
ADHD cause unlikely to be dopamine dysfunction
Source: Mental Health News From Medical News Today [2013.10.29]
A new study by the University of Cambridge in the UK questions the widely held view that dysfunction in dopamine - a chemical that controls the brain's reward and pleasure centers - is the main cause of ADHD, a condition characterized by inattentiveness, hyperactivity and impulsiveness.
Dopamine Imbalance In Huntington's Disease: A Mechanism For The Lack Of Behavioral Flexibility
Source: Huntingtons Disease News From Medical News Today [2013.07.08]
Huntington's disease is a hereditary neurodegenerative disease that is caused by a mutation in the human huntingtin gene. It is characterized by uncontrollable dance-like movements (chorea) in the early stages of the disease and loss of voluntary movement (behavioral inflexibility) in the later stages.
Mutations that predispose an individual to increased risk of Parkinson's disease from pesticides
Source: Genetics News From Medical News Today [2013.12.02]
Study uses patient-derived stem cells to show that a mutation in the alpha-synuclein gene causes increased vulnerability to pesticides, leading to Parkinson's disease.A team of researchers has brought new clarity to the picture of how gene-environmental interactions can kill nerve cells that make dopamine.
Source: MedicineNet Helicobacter Pylori Specialty [2012.05.16]
Title: Peptic Ulcer
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 5/16/2012 12:00:00 AM
Published Studies Related to Pamine (Methscopolamine)
Methscopolamine bromide blocks hypothalamic-stimulated release of growth hormone in ewes. [1997.05]
Twenty-five nonlactating ewes were used to test the hypothesis that methscopolamine bromide (MB) blocks secretion of growth hormone (GH) by affecting hypothalamic rather than pituitary mechanisms. Ewes were randomly assigned to receive a s.c...
The muscarine antagonist methscopolamine and the NMDA antagonist AP-5 injected unilaterally into the nucleus accumbens cause mice to rotate in opposite directions. 
Previously, we have reported that the NMDA antagonist AP-5, injected unilaterally into the nucleus accumbens of mice, induces ipsilateral rotation in monoaminergically intact mice, but contralateral rotation in monoamine-depleted animals. In this paper we report that the muscarine antagonist methscopolamine, injected unilaterally into the nucleus accumbens, induced predominantly contralateral rotation in monoaminergically intact mice...
Dorsal striatal mechanisms involved in the dopamine D2 receptor-mediated potentiation of apomorphine-induced jaw movements. [1994.01.24]
The role of dorsal striatal mechanisms in the regulation of apomorphine-induced jaw movements was studied. Jaw movements induced by apomorphine (0.2 mg/kg i.v.) were potentiated by quinpirole (10 micrograms/0.2 microliter) injected into the dorsal part of the striatum 10 min before apomorphine...
Seizure promotion by D1 agonists does not correlate with other dopaminergic properties. 
A range of D1 receptor agonists were tested for their ability to facilitate limbic motor seizures induced by a subthreshold dose of the chemoconvulsant pilocarpine (100 mg/kg IP) in mice. ED50 values (mumol/kg) were calculated from log dose-probit analyses, giving relative proconvulsant potencies of SKF 82958 > CY 208-243 > SKF 77434 = SKF 75670 = SKF 80723 > SKF 38393...