Pamine® 2.5 mg/Pamine® Forte 5 mg
Pamine® 2.5 mg/Pamine® Forte 5 mg Tablets contain methscopolamine bromide, an anticholinergic, which occurs as white crystals, or as a white odorless crystalline powder. Methscopolamine bromide melts at about 225°C with decomposition. The drug is freely soluble in water, slightly soluble in alcohol, and insoluble in acetone and in chloroform.
PAMINE (METHSCOPOLAMINE) is indicated for the following:
Adjunctive therapy for the treatment of peptic ulcer.
METHSCOPOLAMINE BROMIDE HAS NOT BEEN SHOWN TO BE EFFECTIVE IN CONTRIBUTING TO THE HEALING OF PEPTIC ULCER, DECREASING THE RATE OF RECURRENCE OR PREVENTING COMPLICATIONS.
Media Articles Related to Pamine (Methscopolamine)
Researchers uncover how dopamine transports within the brain
Source: Alcohol / Addiction / Illegal Drugs News From Medical News Today [2016.01.25]
Researchers at University of Florida Health have discovered the mechanics of how dopamine transports into and out of brain cells, a finding that could someday lead to more effective treatment of...
Unexpected connections: Calcium refill mechanisms in nerve cells affects gene expression
Source: ADHD / ADD News From Medical News Today [2015.10.08]
Researchers at the National Centre for Biological Sciences, identify new roles for calcium refill mechanisms in regulating dopamine in the brainThese are dopaminergic neuron clusters (green) of...
Source: MedicineNet Bernard-Soulier Disease Specialty [2014.07.17]
Title: Peptic Ulcer
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 7/17/2014 12:00:00 AM
Novel insights in the attachment of the bacterial carcinogen Helicobacter pylori
Source: GastroIntestinal / Gastroenterology News From Medical News Today [2016.01.14]
The gastric pathogen Helicobacter pylori is highly adapted to survival in the human stomach and responsible for the majority of peptic ulcer and gastric cancer cases worldwide.
Published Studies Related to Pamine (Methscopolamine)
Methscopolamine bromide blocks hypothalamic-stimulated release of growth hormone in ewes. [1997.05]
Twenty-five nonlactating ewes were used to test the hypothesis that methscopolamine bromide (MB) blocks secretion of growth hormone (GH) by affecting hypothalamic rather than pituitary mechanisms. Ewes were randomly assigned to receive a s.c...
The muscarine antagonist methscopolamine and the NMDA antagonist AP-5 injected unilaterally into the nucleus accumbens cause mice to rotate in opposite directions. 
Previously, we have reported that the NMDA antagonist AP-5, injected unilaterally into the nucleus accumbens of mice, induces ipsilateral rotation in monoaminergically intact mice, but contralateral rotation in monoamine-depleted animals. In this paper we report that the muscarine antagonist methscopolamine, injected unilaterally into the nucleus accumbens, induced predominantly contralateral rotation in monoaminergically intact mice...
Dorsal striatal mechanisms involved in the dopamine D2 receptor-mediated potentiation of apomorphine-induced jaw movements. [1994.01.24]
The role of dorsal striatal mechanisms in the regulation of apomorphine-induced jaw movements was studied. Jaw movements induced by apomorphine (0.2 mg/kg i.v.) were potentiated by quinpirole (10 micrograms/0.2 microliter) injected into the dorsal part of the striatum 10 min before apomorphine...
Seizure promotion by D1 agonists does not correlate with other dopaminergic properties. 
A range of D1 receptor agonists were tested for their ability to facilitate limbic motor seizures induced by a subthreshold dose of the chemoconvulsant pilocarpine (100 mg/kg IP) in mice. ED50 values (mumol/kg) were calculated from log dose-probit analyses, giving relative proconvulsant potencies of SKF 82958 > CY 208-243 > SKF 77434 = SKF 75670 = SKF 80723 > SKF 38393...