Pamine® 2.5 mg/Pamine® Forte 5 mg Tablets
Pamine® 2.5 mg/Pamine® Forte 5 mg Tablets contain methscopolamine bromide, an anticholinergic agent.
Pamine (methscopolamine cation) is indicated for the following:
Adjunctive therapy for the treatment of peptic ulcer.
METHSCOPOLAMINE BROMIDE HAS NOT BEEN SHOWN TO BE EFFECTIVE IN CONTRIBUTING TO THE HEALING OF PEPTIC ULCER, DECREASING THE RATE OF RECURRENCE OR PREVENTING COMPLICATIONS.
Media Articles Related to Pamine (Methscopolamine)
Dopamine signals the value of delayed rewards
Source: Endocrinology News From Medical News Today [2015.05.12]
Dopamine is the chemical messenger in the brain most closely associated with pleasure and reward. Recent scientific advances now shed light on precise roles for dopamine in the reward process.
Study shows dopamine may play role in chronic pain
Source: Pain / Anesthetics News From Medical News Today [2015.05.11]
In chronic pain, nerve cells continue to send pain signals to brain even in absence of injury. Now, a new study reveals how dopamine-containing cells may contribute to this state.
Nerve cells in the fast lane
Source: Schizophrenia News From Medical News Today [2015.05.15]
Dopamine-producing neurons fulfil important function in the brainNerve cells that produce dopamine for the purpose of transmitting signals to other cells affect numerous crucial brain functions.
Scientists reconcile three unrelated theories of schizophrenia
Source: Schizophrenia News From Medical News Today [2015.05.06]
Mouse model will help scientists parse brain-based findingsOveractive neurons in the front of the mouse brain, shown in green, trigger excessive release of the brain chemical dopamine, which...
Rates of ADHD appear to decrease at higher altitudes
Source: ADHD / ADD News From Medical News Today [2015.04.10]
Higher levels of dopamine might play a role, researchers believeRecent research has linked the thin air of higher elevations to increased rates of depression and suicide.
Published Studies Related to Pamine (Methscopolamine)
Methscopolamine bromide blocks hypothalamic-stimulated release of growth hormone in ewes. [1997.05]
Twenty-five nonlactating ewes were used to test the hypothesis that methscopolamine bromide (MB) blocks secretion of growth hormone (GH) by affecting hypothalamic rather than pituitary mechanisms. Ewes were randomly assigned to receive a s.c...
The muscarine antagonist methscopolamine and the NMDA antagonist AP-5 injected unilaterally into the nucleus accumbens cause mice to rotate in opposite directions. 
Previously, we have reported that the NMDA antagonist AP-5, injected unilaterally into the nucleus accumbens of mice, induces ipsilateral rotation in monoaminergically intact mice, but contralateral rotation in monoamine-depleted animals. In this paper we report that the muscarine antagonist methscopolamine, injected unilaterally into the nucleus accumbens, induced predominantly contralateral rotation in monoaminergically intact mice...
Dorsal striatal mechanisms involved in the dopamine D2 receptor-mediated potentiation of apomorphine-induced jaw movements. [1994.01.24]
The role of dorsal striatal mechanisms in the regulation of apomorphine-induced jaw movements was studied. Jaw movements induced by apomorphine (0.2 mg/kg i.v.) were potentiated by quinpirole (10 micrograms/0.2 microliter) injected into the dorsal part of the striatum 10 min before apomorphine...
Seizure promotion by D1 agonists does not correlate with other dopaminergic properties. 
A range of D1 receptor agonists were tested for their ability to facilitate limbic motor seizures induced by a subthreshold dose of the chemoconvulsant pilocarpine (100 mg/kg IP) in mice. ED50 values (mumol/kg) were calculated from log dose-probit analyses, giving relative proconvulsant potencies of SKF 82958 > CY 208-243 > SKF 77434 = SKF 75670 = SKF 80723 > SKF 38393...