PAMINE SUMMARY
Pamine® 2.5 mg/Pamine® Forte 5 mg Tablets
Pamine® 2.5 mg/Pamine® Forte 5 mg Tablets contain methscopolamine bromide, an anticholinergic agent.
Pamine (methscopolamine cation) is indicated for the following:
Adjunctive therapy for the treatment of peptic ulcer.
METHSCOPOLAMINE BROMIDE HAS NOT BEEN SHOWN TO BE EFFECTIVE IN CONTRIBUTING TO THE HEALING OF PEPTIC ULCER, DECREASING THE RATE OF RECURRENCE OR PREVENTING COMPLICATIONS.
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NEWS HIGHLIGHTSMedia Articles Related to Pamine (Methscopolamine)
Brain Dopamine Transporter Levels Increased By Long-term ADHD Treatment
Source: ADHD News From Medical News Today [2013.05.17]
Long-term treatment of attention deficit/hyperactivity disorder (ADHD) with certain stimulant medications may alter the density of the dopamine transporter, according to research published in the open access journal PLOS ONE by Gene-Jack Wang and colleagues from Brookhaven National Laboratory and the intramural program at NIH...
Possible Link Between Childhood Obesity And ADHD, Learning Disabilities
Source: ADHD News From Medical News Today [2013.02.22]
A University of Illinois study has established a possible link between high-fat diets and such childhood brain-based conditions as attention deficit hyperactivity disorder (ADHD) and memory-dependent learning disabilities. "We found that a high-fat diet rapidly affected dopamine metabolism in the brains of juvenile mice, triggering anxious behaviors and learning deficiencies...
Peptic Ulcer
Source: MedicineNet Helicobacter Pylori Specialty [2012.05.16]
Title: Peptic Ulcer
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 5/16/2012 12:00:00 AM
Picture of Peptic Ulcer
Source: MedicineNet famotidine Specialty [2010.04.15]
Title: Picture of Peptic Ulcer
Category: Images
Created: 4/15/2010 9:58:00 AM
Last Editorial Review: 4/15/2010 9:58:47 AM
Published Studies Related to Pamine (Methscopolamine)
Methscopolamine bromide blocks hypothalamic-stimulated release of growth hormone in ewes. [1997.05]
Twenty-five nonlactating ewes were used to test the hypothesis that methscopolamine bromide (MB) blocks secretion of growth hormone (GH) by affecting hypothalamic rather than pituitary mechanisms. Ewes were randomly assigned to receive a s.c...
The muscarine antagonist methscopolamine and the NMDA antagonist AP-5 injected unilaterally into the nucleus accumbens cause mice to rotate in opposite directions. [1995]
Previously, we have reported that the NMDA antagonist AP-5, injected unilaterally into the nucleus accumbens of mice, induces ipsilateral rotation in monoaminergically intact mice, but contralateral rotation in monoamine-depleted animals. In this paper we report that the muscarine antagonist methscopolamine, injected unilaterally into the nucleus accumbens, induced predominantly contralateral rotation in monoaminergically intact mice...
Dorsal striatal mechanisms involved in the dopamine D2 receptor-mediated potentiation of apomorphine-induced jaw movements. [1994.01.24]
The role of dorsal striatal mechanisms in the regulation of apomorphine-induced jaw movements was studied. Jaw movements induced by apomorphine (0.2 mg/kg i.v.) were potentiated by quinpirole (10 micrograms/0.2 microliter) injected into the dorsal part of the striatum 10 min before apomorphine...
Seizure promotion by D1 agonists does not correlate with other dopaminergic properties. [1993]
A range of D1 receptor agonists were tested for their ability to facilitate limbic motor seizures induced by a subthreshold dose of the chemoconvulsant pilocarpine (100 mg/kg IP) in mice. ED50 values (mumol/kg) were calculated from log dose-probit analyses, giving relative proconvulsant potencies of SKF 82958 > CY 208-243 > SKF 77434 = SKF 75670 = SKF 80723 > SKF 38393...
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