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Pamine (Methscopolamine Bromide) - Summary

 
 



PAMINE SUMMARY

Pamine® 2.5 mg/Pamine® Forte 5 mg Tablets

Pamine 2.5 mg/Pamine Forte 5 mg Tablets contain methscopolamine bromide, an anticholinergic agent.

Pamine (methscopolamine cation) is indicated for the following:

Adjunctive therapy for the treatment of peptic ulcer.

METHSCOPOLAMINE BROMIDE HAS NOT BEEN SHOWN TO BE EFFECTIVE IN CONTRIBUTING TO THE HEALING OF PEPTIC ULCER, DECREASING THE RATE OF RECURRENCE OR PREVENTING COMPLICATIONS.


See all Pamine indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Pamine (Methscopolamine)

Schizophrenia: Impaired activity of the selective dopamine neurons
Source: Schizophrenia News From Medical News Today [2015.02.19]
German-American team of researchers finds neurophysiological correlates for cognitive and emotional symptoms in a Schizophrenia mouse model.

Study on dopamine neurons could instruct research into mobility and neurological disorders
Source: Schizophrenia News From Medical News Today [2015.02.02]
University of Leicester team find for the first time when and why dopamine releasing cells in the forebrain are activated Dopamine releasing cells in the forebrain are difficult to access in...

New Internal Clock Identified
Source: Medscape Psychiatry & Mental Health Headlines [2015.02.27]
Researchers have identified a second internal clock in the brain that is desynchronized by changes in dopamine tone, leading to aberrant patterns of arousal similar those in bipolar disorder.
Medscape Medical News

Parkinson's trial suggests growth factor has regenerative effects in brain
Source: Biology / Biochemistry News From Medical News Today [2015.02.19]
Small trial to test safety and tolerability of the growth factor PDGF in Parkinson's patients finds it not only stops deterioration of dopamine signaling, but may even increase it.

Common pesticide may increase risk of ADHD
Source: ADHD News From Medical News Today [2015.02.02]
Rutgers study suggests that pregnant women and young children are more susceptibleA commonly used pesticide may alter the development of the brain's dopamine system -- responsible for emotional...

more news >>

Published Studies Related to Pamine (Methscopolamine)

Methscopolamine bromide blocks hypothalamic-stimulated release of growth hormone in ewes. [1997.05]
Twenty-five nonlactating ewes were used to test the hypothesis that methscopolamine bromide (MB) blocks secretion of growth hormone (GH) by affecting hypothalamic rather than pituitary mechanisms. Ewes were randomly assigned to receive a s.c...

The muscarine antagonist methscopolamine and the NMDA antagonist AP-5 injected unilaterally into the nucleus accumbens cause mice to rotate in opposite directions. [1995]
Previously, we have reported that the NMDA antagonist AP-5, injected unilaterally into the nucleus accumbens of mice, induces ipsilateral rotation in monoaminergically intact mice, but contralateral rotation in monoamine-depleted animals. In this paper we report that the muscarine antagonist methscopolamine, injected unilaterally into the nucleus accumbens, induced predominantly contralateral rotation in monoaminergically intact mice...

Dorsal striatal mechanisms involved in the dopamine D2 receptor-mediated potentiation of apomorphine-induced jaw movements. [1994.01.24]
The role of dorsal striatal mechanisms in the regulation of apomorphine-induced jaw movements was studied. Jaw movements induced by apomorphine (0.2 mg/kg i.v.) were potentiated by quinpirole (10 micrograms/0.2 microliter) injected into the dorsal part of the striatum 10 min before apomorphine...

Seizure promotion by D1 agonists does not correlate with other dopaminergic properties. [1993]
A range of D1 receptor agonists were tested for their ability to facilitate limbic motor seizures induced by a subthreshold dose of the chemoconvulsant pilocarpine (100 mg/kg IP) in mice. ED50 values (mumol/kg) were calculated from log dose-probit analyses, giving relative proconvulsant potencies of SKF 82958 > CY 208-243 > SKF 77434 = SKF 75670 = SKF 80723 > SKF 38393...

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Page last updated: 2015-02-27

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