Pamine® 2.5 mg/Pamine® Forte 5 mg
Pamine® 2.5 mg/Pamine® Forte 5 mg Tablets contain methscopolamine bromide, an anticholinergic, which occurs as white crystals, or as a white odorless crystalline powder. Methscopolamine bromide melts at about 225°C with decomposition. The drug is freely soluble in water, slightly soluble in alcohol, and insoluble in acetone and in chloroform.
PAMINE (METHSCOPOLAMINE) is indicated for the following:
Adjunctive therapy for the treatment of peptic ulcer.
METHSCOPOLAMINE BROMIDE HAS NOT BEEN SHOWN TO BE EFFECTIVE IN CONTRIBUTING TO THE HEALING OF PEPTIC ULCER, DECREASING THE RATE OF RECURRENCE OR PREVENTING COMPLICATIONS.
Media Articles Related to Pamine (Methscopolamine)
Medication against schizophrenia inhibits pancreatic cancer
Source: Schizophrenia News From Medical News Today [2016.09.09]
A receptor for the dopamine neurotransmitter promotes growth and spread of pancreatic cancer - and schizophrenia drugs, which block the function of this receptor, slowed tumor growth and metastatic...
Even Without PPI, Oozing Peptic Ulcers Rarely Rebleed After Endoscopic Hemostasis
Source: Medscape Gastroenterology Headlines [2017.02.16]
The rebleeding rate of oozing peptic ulcer bleeds (PUB) after successful endoscopic therapy is low, and 72 hours of IV proton pump inhibitor (PPI) does not lower the rate further, according to results of a large multinational randomized trial.
Reuters Health Information
Peptic Ulcer (Stomach Ulcer)
Source: MedicineNet Antiemetics Specialty [2016.08.03]
Title: Peptic Ulcer (Stomach Ulcer)
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 8/3/2016 12:00:00 AM
Stomach Ulcer (Peptic Ulcer)
Source: MedicineNet cimetidine Specialty [2016.08.02]
Title: Stomach Ulcer (Peptic Ulcer)
Category: Symptoms and Signs
Created: 12/4/2013 12:00:00 AM
Last Editorial Review: 8/2/2016 12:00:00 AM
Published Studies Related to Pamine (Methscopolamine)
Methscopolamine bromide blocks hypothalamic-stimulated release of growth hormone in ewes. [1997.05]
Twenty-five nonlactating ewes were used to test the hypothesis that methscopolamine bromide (MB) blocks secretion of growth hormone (GH) by affecting hypothalamic rather than pituitary mechanisms. Ewes were randomly assigned to receive a s.c...
The muscarine antagonist methscopolamine and the NMDA antagonist AP-5 injected unilaterally into the nucleus accumbens cause mice to rotate in opposite directions. 
Previously, we have reported that the NMDA antagonist AP-5, injected unilaterally into the nucleus accumbens of mice, induces ipsilateral rotation in monoaminergically intact mice, but contralateral rotation in monoamine-depleted animals. In this paper we report that the muscarine antagonist methscopolamine, injected unilaterally into the nucleus accumbens, induced predominantly contralateral rotation in monoaminergically intact mice...
Dorsal striatal mechanisms involved in the dopamine D2 receptor-mediated potentiation of apomorphine-induced jaw movements. [1994.01.24]
The role of dorsal striatal mechanisms in the regulation of apomorphine-induced jaw movements was studied. Jaw movements induced by apomorphine (0.2 mg/kg i.v.) were potentiated by quinpirole (10 micrograms/0.2 microliter) injected into the dorsal part of the striatum 10 min before apomorphine...
Seizure promotion by D1 agonists does not correlate with other dopaminergic properties. 
A range of D1 receptor agonists were tested for their ability to facilitate limbic motor seizures induced by a subthreshold dose of the chemoconvulsant pilocarpine (100 mg/kg IP) in mice. ED50 values (mumol/kg) were calculated from log dose-probit analyses, giving relative proconvulsant potencies of SKF 82958 > CY 208-243 > SKF 77434 = SKF 75670 = SKF 80723 > SKF 38393...