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Pamine (Methscopolamine Bromide) - Summary



Pamine® 2.5 mg/Pamine® Forte 5 mg

Pamine® 2.5 mg/Pamine® Forte 5 mg Tablets contain methscopolamine bromide, an anticholinergic, which occurs as white crystals, or as a white odorless crystalline powder. Methscopolamine bromide melts at about 225°C with decomposition. The drug is freely soluble in water, slightly soluble in alcohol, and insoluble in acetone and in chloroform.

PAMINE (METHSCOPOLAMINE) is indicated for the following:

Adjunctive therapy for the treatment of peptic ulcer.


See all Pamine indications & dosage >>


Media Articles Related to Pamine (Methscopolamine)

Declining dopamine may explain why older people take fewer risks
Source: Seniors / Aging News From Medical News Today [2016.06.03]
Older people are less willing to take risks for potential rewards and this may be due to declining levels of dopamine in the brain, finds a new UCL study of over 25,000 people funded by Wellcome.

Dopamine key to vocal learning, songbird study finds
Source: Hearing / Deafness News From Medical News Today [2016.03.16]
The neurotransmitter dopamine is essential to correcting vocal mistakes, suggests a study on Bengalese finches.

Obesity linked to abnormal reward response to sugary foods
Source: Obesity / Weight Loss / Fitness News From Medical News Today [2016.06.19]
Preference for sweet treats is influenced by age and dopamine levels in healthy-weight people, but this is not the case for those who are obese.

Peptic Ulcer
Source: MedicineNet Antiemetics Specialty [2016.02.26]
Title: Peptic Ulcer
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 2/26/2016 12:00:00 AM

H. pylori infection may reduce risk of allergic esophageal condition
Source: Allergy News From Medical News Today [2016.03.02]
New research suggests that Helicobacter pylori (H. pylori) infection of the stomach, which occurs in about half of the world's population and can cause peptic ulcers and stomach cancer in minority of...

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Published Studies Related to Pamine (Methscopolamine)

Methscopolamine bromide blocks hypothalamic-stimulated release of growth hormone in ewes. [1997.05]
Twenty-five nonlactating ewes were used to test the hypothesis that methscopolamine bromide (MB) blocks secretion of growth hormone (GH) by affecting hypothalamic rather than pituitary mechanisms. Ewes were randomly assigned to receive a s.c...

The muscarine antagonist methscopolamine and the NMDA antagonist AP-5 injected unilaterally into the nucleus accumbens cause mice to rotate in opposite directions. [1995]
Previously, we have reported that the NMDA antagonist AP-5, injected unilaterally into the nucleus accumbens of mice, induces ipsilateral rotation in monoaminergically intact mice, but contralateral rotation in monoamine-depleted animals. In this paper we report that the muscarine antagonist methscopolamine, injected unilaterally into the nucleus accumbens, induced predominantly contralateral rotation in monoaminergically intact mice...

Dorsal striatal mechanisms involved in the dopamine D2 receptor-mediated potentiation of apomorphine-induced jaw movements. [1994.01.24]
The role of dorsal striatal mechanisms in the regulation of apomorphine-induced jaw movements was studied. Jaw movements induced by apomorphine (0.2 mg/kg i.v.) were potentiated by quinpirole (10 micrograms/0.2 microliter) injected into the dorsal part of the striatum 10 min before apomorphine...

Seizure promotion by D1 agonists does not correlate with other dopaminergic properties. [1993]
A range of D1 receptor agonists were tested for their ability to facilitate limbic motor seizures induced by a subthreshold dose of the chemoconvulsant pilocarpine (100 mg/kg IP) in mice. ED50 values (mumol/kg) were calculated from log dose-probit analyses, giving relative proconvulsant potencies of SKF 82958 > CY 208-243 > SKF 77434 = SKF 75670 = SKF 80723 > SKF 38393...

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Page last updated: 2016-06-19

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