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Pamine (Methscopolamine Bromide) - Summary

 
 



PAMINE SUMMARY

Pamine® 2.5 mg/Pamine® Forte 5 mg Tablets

Pamine 2.5 mg/Pamine Forte 5 mg Tablets contain methscopolamine bromide, an anticholinergic agent.

Pamine (methscopolamine cation) is indicated for the following:

Adjunctive therapy for the treatment of peptic ulcer.

METHSCOPOLAMINE BROMIDE HAS NOT BEEN SHOWN TO BE EFFECTIVE IN CONTRIBUTING TO THE HEALING OF PEPTIC ULCER, DECREASING THE RATE OF RECURRENCE OR PREVENTING COMPLICATIONS.


See all Pamine indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Pamine (Methscopolamine)

Reports of pathological gambling, hypersexuality, compulsive shopping associated with dopamine agonist drugs
Source: Alcohol / Addiction / Illegal Drugs News From Medical News Today [2014.10.21]
During a 10-year period, there were 1,580 adverse drug events reported in the United States and 21 other countries that indicated impulse control disorders in patients, including 628 cases of...

Serious Impulse Control Disorders With Dopamine Agonists
Source: Medscape NeurologyHeadlines [2014.10.20]
Researchers 'confirm and extend' evidence for the link between serious impulse control disorders, such as compulsive shopping and gambling and hypersexuality, and all 6 dopamine agonists used to treat Parkinson's disease.
Medscape Medical News

Eating breakfast reduces cravings, overeating
Source: Obesity / Weight Loss / Fitness News From Medical News Today [2014.10.16]
Researchers find the increase in dopamine levels in the brain that result from eating protein-rich breakfasts may reduce food cravings and overeating later in the day.

Supercomputer used to study a common link between addiction and neurological disease
Source: ADHD News From Medical News Today [2014.07.25]
Recent published research in the Journal of Clinical Investigation demonstrates how changes in dopamine signaling and dopamine transporter function are linked to neurological and psychiatric...

Peptic Ulcer
Source: MedicineNet Antiemetics Specialty [2014.07.17]
Title: Peptic Ulcer
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 7/17/2014 12:00:00 AM

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Published Studies Related to Pamine (Methscopolamine)

Methscopolamine bromide blocks hypothalamic-stimulated release of growth hormone in ewes. [1997.05]
Twenty-five nonlactating ewes were used to test the hypothesis that methscopolamine bromide (MB) blocks secretion of growth hormone (GH) by affecting hypothalamic rather than pituitary mechanisms. Ewes were randomly assigned to receive a s.c...

The muscarine antagonist methscopolamine and the NMDA antagonist AP-5 injected unilaterally into the nucleus accumbens cause mice to rotate in opposite directions. [1995]
Previously, we have reported that the NMDA antagonist AP-5, injected unilaterally into the nucleus accumbens of mice, induces ipsilateral rotation in monoaminergically intact mice, but contralateral rotation in monoamine-depleted animals. In this paper we report that the muscarine antagonist methscopolamine, injected unilaterally into the nucleus accumbens, induced predominantly contralateral rotation in monoaminergically intact mice...

Dorsal striatal mechanisms involved in the dopamine D2 receptor-mediated potentiation of apomorphine-induced jaw movements. [1994.01.24]
The role of dorsal striatal mechanisms in the regulation of apomorphine-induced jaw movements was studied. Jaw movements induced by apomorphine (0.2 mg/kg i.v.) were potentiated by quinpirole (10 micrograms/0.2 microliter) injected into the dorsal part of the striatum 10 min before apomorphine...

Seizure promotion by D1 agonists does not correlate with other dopaminergic properties. [1993]
A range of D1 receptor agonists were tested for their ability to facilitate limbic motor seizures induced by a subthreshold dose of the chemoconvulsant pilocarpine (100 mg/kg IP) in mice. ED50 values (mumol/kg) were calculated from log dose-probit analyses, giving relative proconvulsant potencies of SKF 82958 > CY 208-243 > SKF 77434 = SKF 75670 = SKF 80723 > SKF 38393...

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Page last updated: 2014-10-21

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