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Palladone (Hydromorphone Hydrochloride) - Published Studies

 
 



Palladone Related Published Studies

Well-designed clinical trials related to Palladone (Hydromorphone)

Potency ratio of hydromorphone and diacetylmorphine in substitution treatment for long-term opioid dependency. [2011]

Effects of acepromazine, hydromorphone, or an acepromazine-hydromorphone combination on the degree of sedation in clinically normal dogs. [2010.11.15]

Steady-state pharmacokinetics of extended-release hydromorphone (OROS hydromorphone): a randomized study in healthy volunteers. [2010.09]

A randomized study to demonstrate noninferiority of once-daily OROS((R)) hydromorphone with twice-daily sustained-release oxycodone for moderate to severe chronic noncancer pain. [2010.09]

Once-daily OROS hydromorphone ER compared with placebo in opioid-tolerant patients with chronic low back pain. [2010.06]

Double-blind injectable hydromorphone versus diacetylmorphine for the treatment of opioid dependence: a pilot study. [2010.06]

Evaluation of the abuse potential of extended release hydromorphone versus immediate release hydromorphone. [2010.02]

A comparison of the effects of hydromorphone HCl and a novel extended release hydromorphone on arterial blood gas values in conscious healthy dogs. [2010.02]

Once-daily OROS hydromorphone ER compared with placebo in opioid-tolerant patients with chronic low back pain. [2010]

Double-blind injectable hydromorphone versus diacetylmorphine for the treatment of opioid dependence: a pilot study. [2010]

Evaluation of the abuse potential of extended release hydromorphone versus immediate release hydromorphone. [2010]

Randomized clinical trial comparing a patient-driven titration protocol of intravenous hydromorphone with traditional physician-driven management of emergency department patients with acute severe pain. [2009.10]

Gastrointestinal symptoms under opioid therapy: a prospective comparison of oral sustained-release hydromorphone, transdermal fentanyl, and transdermal buprenorphine. [2009.08]

Efficacy and safety profile of a single dose of hydromorphone compared with morphine in older adults with acute, severe pain: a prospective, randomized, double-blind clinical trial. [2009.02]

A randomized, double-blind comparison of OROS(R) hydromorphone and controlled-release morphine for the control of chronic cancer pain. [2008.10.31]

The side effects of morphine and hydromorphone patient-controlled analgesia. [2008.10]

Relief of incident dyspnea in palliative cancer patients: a pilot, randomized, controlled trial comparing nebulized hydromorphone, systemic hydromorphone, and nebulized saline. [2008.07]

Comparison of the analgesic efficacy of hydromorphone and oxymorphone in dogs and cats: a randomized blinded study. [2008.07]

Relief of Incident Dyspnea in Palliative Cancer Patients: A Pilot, Randomized, Controlled Trial Comparing Nebulized Hydromorphone, Systemic Hydromorphone, and Nebulized Saline. [2008.03.19]

Conversion from standard opioid therapy to once-daily oral extended-release hydromorphone in patients with chronic cancer pain. [2008.03]

Pharmacokinetic profile of a 24-hour controlled-release OROS formulation of hydromorphone in the presence of alcohol. [2008.01]

Metoclopramide versus hydromorphone for the emergency department treatment of migraine headache. [2008.01]

Metoclopramide Versus Hydromorphone for the Emergency Department Treatment of Migraine Headache. [2007.11.02]

A comparison of single-dose caudal clonidine, morphine, or hydromorphone combined with ropivacaine in pediatric patients undergoing ureteral reimplantation. [2007.06]

Efficacy and tolerability of once-daily OROS hydromorphone and twice-daily extended-release oxycodone in patients with chronic, moderate to severe osteoarthritis pain: results of a 6-week, randomized, open-label, noninferiority analysis. [2007.05]

Dose-related thermal antinociceptive effects of intravenous hydromorphone in cats. [2007.03]

Pharmacokinetic investigation of dose proportionality with a 24-hour controlled-release formulation of hydromorphone. [2007.02.02]

Safety and efficacy of hydromorphone as an analgesic alternative to morphine in acute pain: a randomized clinical trial. [2006.08]

Effects of oxymorphone and hydromorphone on the minimum alveolar concentration of isoflurane in dogs. [2006.01]

Comparative efficacy of oral extended-release hydromorphone and immediate-release hydromorphone in patients with persistent moderate to severe pain: two randomized controlled trials. [2005.06]

Clinical pharmacology and pharmacokinetics of once-daily hydromorphone hydrochloride extended-release capsules. [2005.05]

Well-designed clinical trials possibly related to Palladone (Hydromorphone)

Relationship of negative affect and outcome of an opioid therapy trial among low back pain patients. [2013]

PCA-derived factors that may be predictive of postoperative pain in pediatric patients: a possible role for the PCA ratio. [2012]

Addition of pregabalin to multimodal analgesic therapy following ankle surgery: a randomized double-blind, placebo-controlled trial. [2012]

Nerve stimulator versus ultrasound guidance for placement of popliteal catheters for foot and ankle surgery. [2012]

The effects of preoperative intravenous acetaminophen in patients undergoing abdominal hysterectomy. [2011.12]

Intra- and postoperative very low dose intravenous ketamine infusion does not increase pain relief after major spine surgery in patients with preoperative narcotic analgesic intake. [2011.08]

Client satisfaction among participants in a randomized trial comparing oral methadone and injectable diacetylmorphine for long-term opioid-dependency. [2011.07.26]

Discriminative stimulus effects of tramadol in humans. [2011.07]

Evaluation of dexmedetomidine and ketamine in combination with opioids as injectable anesthesia for castration in dogs. [2011.05.01]

A comparison of epidural morphine with low dose bupivacaine versus epidural morphine alone on motor and respiratory function in dogs following splenectomy. [2011.05]

A comparison of sartorius versus quadriceps stimulation for femoral nerve block: a prospective randomized double-blind controlled trial. [2011.03]

History of reported sexual or physical abuse among long-term heroin users and their response to substitution treatment. [2011.01]

Client satisfaction among participants in a randomized trial comparing oral methadone and injectable diacetylmorphine for long-term opioid-dependency. [2011]

The effects of preoperative intravenous acetaminophen in patients undergoing abdominal hysterectomy. [2011]

History of reported sexual or physical abuse among long-term heroin users and their response to substitution treatment. [2011]

A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery. [2010.12]

An enhanced bunionectomy model as a potential tool for early decision-making in the development of new analgesics. [2010.12]

Sustained release d-amphetamine reduces cocaine but not 'speedball'-seeking in buprenorphine-maintained volunteers: a test of dual-agonist pharmacotherapy for cocaine/heroin polydrug abusers. [2010.12]

The influence of time of day of administration on duration of opioid labor analgesia. [2010.10]

History of reported sexual or physical abuse among long-term heroin users and their response to substitution treatment. [2010.09.18]

Effectiveness of injection of local anesthetic into the retrobulbar space for postoperative analgesia following eye enucleation in dogs. [2010.07.15]

Characteristics and response to treatment among Aboriginal people receiving heroin-assisted treatment. [2010.05]

Comparison of the prophylactic anti-emetic efficacy of ramosetron and ondansetron in patients at high-risk for postoperative nausea and vomiting after total knee replacement. [2010.05]

Effects of opioids and anesthetic drugs on body temperature in cats. [2010.01]

Behavioral economic analysis of opioid consumption in heroin-dependent individuals: effects of alternative reinforcer magnitude and post-session drug supply. [2009.09.01]

Epidural analgesia compared with intravenous analgesia after pediatric posterior spinal fusion. [2009.09]

Diacetylmorphine versus methadone for the treatment of opioid addiction. [2009.08.20]

Scientific and political challenges in North America's first randomized controlled trial of heroin-assisted treatment for severe heroin addiction: rationale and design of the NAOMI study. [2009.06]

Within-subject comparison of the psychopharmacological profiles of oral hydrocodone and oxycodone combination products in non-drug-abusing volunteers. [2009.04.01]

The hypoalgesic effect of oxycodone in human experimental pain models in relation to the CYP2D6 oxidation polymorphism. [2009.04]

The pain quality response profile of oxymorphone extended release in the treatment of low back pain. [2009.02]

Oxymorphone extended release for the treatment of chronic low back pain: a retrospective pooled analysis of enriched-enrollment clinical trial data stratified according to age, sex, and prior opioid use. [2009.02]

Continuous lumbar plexus block for postoperative pain control after total hip arthroplasty. A randomized controlled trial. [2009.01]

Brain dopamine response in human opioid addiction. [2008.07]

Effect of orally administered tramadol alone or with an intravenously administered opioid on minimum alveolar concentration of sevoflurane in cats. [2008.06.15]

A randomized double-blind crossover comparison of continuous and intermittent subcutaneous administration of opioid for cancer pain. [2008.05]

The use of dexamethasone to reduce pain after tonsillectomy in adults: a double-blind prospective randomized trial. [2008.02]

Ketamine as an adjunct to postoperative pain management in opioid tolerant patients after spinal fusions: a prospective randomized trial. [2008.02]

Pentoxifylline after conservative surgery for endometriosis: a randomized, controlled trial. [2008.01]

Femoral nerve block for diaphyseal and distal femoral fractures in the emergency department. [2007.12]

The Use of Dexamethasone to Reduce Pain After Tonsillectomy in Adults: A Double-Blind Prospective Randomized Trial. [2007.11.26]

Randomized trial comparing 3 methods of postoperative analgesia in gynecology patients: patient-controlled intravenous, scheduled intravenous, and scheduled subcutaneous. [2007.11]

Mapping MOS Sleep Scale scores to SF-6D utility index. [2007.09]

Efficacy and tolerability of oxymorphone immediate release for acute postoperative pain after abdominal surgery: a randomized, double-blind, active- and placebo-controlled, parallel-group trial. [2007.06]

The effects of surgery and anesthesia on blood magnesium and calcium concentrations in canine and feline patients. [2007.03]

Buprenorphine duration of action: mu-opioid receptor availability and pharmacokinetic and behavioral indices. [2007.01.01]

A 12-week, randomized, placebo-controlled trial assessing the safety and efficacy of oxymorphone extended release for opioid-naive patients with chronic low back pain. [2007.01]

Effects associated with double-blind omission of buprenorphine/naloxone over a 98-h period. [2006.12]

The effect of nitrous oxide on halothane, isoflurane and sevoflurane requirements in ventilated dogs undergoing ovariohysterectomy. [2006.11]

Behavioral economic analysis of opioid consumption in heroin-dependent individuals: effects of unit price and pre-session drug supply. [2006.10.15]

Continuous femoral nerve block versus intra-articular injection for pain control after anterior cruciate ligament reconstruction. [2006.08]

A 2-week, multicenter, randomized, double-blind, placebo-controlled, dose-ranging, phase III trial comparing the efficacy of oxymorphone extended release and placebo in adults with pain associated with osteoarthritis of the hip or knee. [2006.03]

Evaluation of a single-dose, extended-release epidural morphine formulation for pain after knee arthroplasty. [2006.02]

Comparison of oxycodone pharmacokinetics after buccal and sublingual administration in children. [2006]

Efficacy and safety of oxymorphone immediate release for the treatment of mild to moderate pain after ambulatory orthopedic surgery: results of a randomized, double-blind, placebo-controlled trial. [2005.12]

A prospective, randomized, double-blind study evaluating the efficacy of postoperative continuous local anesthetic infusion at the iliac crest bone graft site after spinal arthrodesis. [2005.11.15]

The effect of preemptive pudendal nerve blockade on pain after transvaginal pelvic reconstructive surgery. [2005.10]

Oxymorphone Extended-Release Tablets Relieve Moderate to Severe Pain and Improve Physical Function in Osteoarthritis: Results of a Randomized, Double-Blind, Placebo- and Active-Controlled Phase III Trial. [2005.09]

The effects of femoral nerve blockade in conjunction with epidural analgesia after total knee arthroplasty. [2005.09]

Acetaminophen decreases early post-thoracotomy ipsilateral shoulder pain in patients with thoracic epidural analgesia: a double-blind placebo-controlled study. [2005.08]

Efficacy of continuous local anesthetic infusion for postoperative pain after radical retropubic prostatectomy. [2005.08]

Comparison of perioperative analgesic protocols for dogs undergoing tibial plateau leveling osteotomy. [2005.07]

Oxymorphone extended release does not affect CYP2C9 or CYP3A4 metabolic pathways. [2005.03]

The risk of cesarean delivery with neuraxial analgesia given early versus late in labor. [2005.02.17]

Efficacy and safety of oxymorphone extended release in chronic low back pain: results of a randomized, double-blind, placebo- and active-controlled phase III study. [2005.01]

Single- and multiple-dose pharmacokinetic and dose-proportionality study of oxymorphone immediate-release tablets. [2005]

Other research related to Palladone (Hydromorphone)

Onset and quality of sedation after intramuscular administration of dexmedetomidine and hydromorphone in various muscle groups in dogs. [2013]

Intradialytic clearance of opioids: methadone versus hydromorphone. [2013]

Evaluation of thermal antinociceptive effects after intramuscular administration of hydromorphone hydrochloride to American kestrels (Falco sparverius). [2013]

Randomized clinical trial of the 2 mg hydromorphone bolus protocol versus the "1+1" hydromorphone titration protocol in treatment of acute, severe pain in the first hour of emergency department presentation. [2013]

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