NEWS HIGHLIGHTSMedia Articles Related to Oxycodone and Aspirin (Oxycodone / Oxycodone / Aspirin)
62-Year-Old Man Becomes First Patient In China Implanted With Rechargeable Neurostimulator For Chronic Pain
Source: Health News from Medical News Today [2009.11.19]
St. Jude Medical, Inc. (NYSE:STJ) announced that a 62-year-old man from Shenzhen, Guangdong province has become the first patient in China to be implanted with the Eon™ neurostimulator, a rechargeable device used to help manage chronic pain. Despite prior back surgeries, the patient suffered from chronic back pain for more than a decade.
Common Pain Relief Medication May Encourage Cancer Growth
Source: Cancer / Oncology News From Medical News Today [2009.11.19]
Although morphine has been the gold-standard treatment for postoperative and chronic cancer pain for two centuries, a growing body of evidence is showing that opiate-based painkillers can stimulate the growth and spread of cancer cells. Two new studies advance that argument and demonstrate how shielding lung cancer cells from opiates reduces cell proliferation, invasion and migration in both cell-culture and mouse models.
CNSBio Inc. To Present Latest Clinical Trial Data For CNSB015 At Neuropathic Pain Conference In San Francisco
Source: Clinical Trials / Drug Trials News From Medical News Today [2009.11.19]
CNSBio Inc. will present recent Phase IIa proof-of-concept clinical trial data for CNSB015, an orally administered potassium channel modulator used in combination with opioids for the treatment of neuropathic pain, at the 12th International Conference on the Mechanisms and Treatment of Neuropathic Pain on November 20-21, 2009 in San Francisco, CA. Dr.
Transplanting People's Own Stem Cells Into Heart Lessens Pain, Improves Ability To Walk
Source: Clinical Trials / Drug Trials News From Medical News Today [2009.11.19]
The largest national stem cell study for heart disease showed the first evidence that transplanting a potent form of adult stem cells into the heart muscle of subjects with severe angina results in less pain and an improved ability to walk. The transplant subjects also experienced fewer deaths than those who didn't receive stem cells.
FDA Approves New Drug For Pain That Persists After Shingles
Source: Dermatology News From Medical News Today [2009.11.18]
The US Food and Drug Administration (FDA) announced yesterday that it has approved Qutenza (capsaicin) 8% patch for the treatment of post-herpetic neuralgia (PHN), an often excruciating pain that can persist for weeks, months and even years in 10 to 15 per cent of people who get shingles. The medicated skin patch, which is made by Lohmann Therapie-Systems AD of Andernach, Germany and distributed in the US by NeurogesX Inc.
Clinical Trials Related to Oxycodone and Aspirin (Oxycodone / Oxycodone / Aspirin)
Oxycodone-Naloxone in Relieving Opioid-Related Constipation [Active, not recruiting]
The primary objective of this study is to demonstrate that subjects with moderate to severe
non-malignant pain taking oxycodone/naloxone prolonged release tablets have improvement in
symptoms of constipation compared to subjects taking oxycodone prolonged release tablets
alone.
Oxycodone-Naloxone Prolonged Release Tablets in Relieving Opioid-Related Constipation [Active, not recruiting]
OXY-1: The Pharmacogenetics of Oxycodone Analgesia in Postoperative Pain [Completed]
Patients undergoing surgery (thyroidectomy and hysterectomy) will postoperatively receive
oxycodone intravenously (IV) as pain management with morphine as an escape medicine, if there
is insufficient pain relief with oxycodone. Patients' pain and side effects will be
registered and after 24 hours they will answer a questionnaire. All included patients will be
genotyped accordingly to CYP2D6 and relevant single nucleotide polymorphisms (SNPs), and
measures of plasma levels of oxycodone will be performed.
OXY-2: The Pharmacogenetics of Oxycodone Analgesia in Human Experimental Pain Models [Completed]
Thirty-two healthy volunteers will be submitted to experimental pain and on the 2 study days
receive Oxycodone 20 mg po vs. placebo. Half of the volunteers will be poor metabolizers
according to CYP2D6 genotype and half will be extensive metabolizers (EM) and have an enzyme
with normal function. The study hypothesis is that PM will experience less pain relief than
EM.
Safety/Efficacy Study of Oxycodone HCl/Niacin to Treat Pain After Bunionectomy [Completed]
The purpose of this study is to determine whether oxycodone HCl and niacin are effective in
the treatment of pain following bunionectomy surgery.
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