Oxycodone and Acetaminophen (Oxycodone / Acetaminophen) - Summary

SUMMARY

Oxycodone and Acetaminophen
Capsules C-II
Revised: January 2004
Rx only
30166-3

Each capsule, for oral administration, contains:

Oxycodone hydrochloride USP 5 mg (equivalent to 4.4815 mg of oxycodone)

Acetaminophen USP 500 mg

The oxycodone component is 14-hydroxydihydrocodeinone, an opiate analgesic.

Acetaminophen, 4’-hydroxyacetanilide, is a non-opiate, non-salicylate analgesic and antipyretic.

Oxycodone and acetaminophen capsules are indicated for the relief of moderate to moderately severe pain.

See all Oxycodone and Acetaminophen indications & dosage >>

NEWS HIGHLIGHTS RELATED TO OXYCODONE AND ACETAMINOPHEN

Published Studies Related to Oxycodone and Acetaminophen (Oxycodone / Acetaminophen)

The effect of single-dose tramadol on oxycodone clearance. [2007.11]

Postoperative intravenous morphine consumption, pain scores, and side effects with perioperative oral controlled-release oxycodone after lumbar discectomy. [2007.07]

Efficacy and tolerability of once-daily OROS hydromorphone and twice-daily extended-release oxycodone in patients with chronic, moderate to severe osteoarthritis pain: results of a 6-week, randomized, open-label, noninferiority analysis. [2007.05]

PTI-821: sustained-release oxycodone using gel-cap technology. [2007.03]

Premedication with controlled-release oxycodone does not improve management of postoperative pain after day-case gynaecological laparoscopic surgery. [2007.02]

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Clinical Trials Related to Oxycodone and Acetaminophen (Oxycodone / Acetaminophen)

Oxycodone-Naloxone in Relieving Opioid-Related Constipation [Active, not recruiting]

Oxycodone-Naloxone Prolonged Release Tablets in Relieving Opioid-Related Constipation [Active, not recruiting]

OXY-1: The Pharmacogenetics of Oxycodone Analgesia in Postoperative Pain [Completed]

OXY-2: The Pharmacogenetics of Oxycodone Analgesia in Human Experimental Pain Models [Completed]

Safety/Efficacy Study of Oxycodone HCl/Niacin to Treat Pain After Bunionectomy [Completed]

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OXYCODONE AND ACETAMINOPHEN PATIENT REVIEWS / RATINGS / COMMENTS

Oxycodone and Acetaminophen review by 49 year old male patient
		Rating
Overall rating:
Effectiveness:		Moderately Effective
Side effects:		Moderate Side Effects
		Treatment Info
Condition / reason:		NECK AND BACK PAIN
Dosage & duration:		5 / 325 TAB MCK - FOUR TIMES PER DAY. taken 4 tablets per day- every six hours for the period of FOR 2 & 1/2 MONTHS AND STILL TAKING IT.
Other conditions:		NONE
Other drugs taken:		NAPROXEN SODIUM
		Reported Results
Benefits:		IT WORKED FOR RELIEVING SOME OF MY NECK AND BACK PAIN. PLEASE NOTE, MY CAUSE OF PAIN WAS DUE TO SURGERY PAIN AND NOT YOUR NORMAL KIND OF BACK PAIN. I MUST SAY THAT IT JUST KIND OF TOOK THE EDGE OFF OF THE SEVERE PAIN I WAS FEELING. AS TIME WENT ON I BEGAN TO HEAL AND FEEL MUCH BETTER AND NOW IT TENDS TO WORK MUCH BETTER.
Side effects:		SOMETIMES TROUBLE BREATHING AND TROUBLE URINATING. ALSO, FELT DROWSY DURING THE DAY. THE BREATHING AND THE URINATING PROBLEMS STOPPED AFTER ABOUT A WEEK ON THIS MEDICATION. AS FOR THE DROWSY FEELING, I STILL EXPERIENCE THAT AND TRY NOT TO DRIVE WHILE ON THIS MEDICATION. I EXPERIENCE NO OTHER SIDE EFFECT EVEN THOUGH I AM STILL TAKING THE MEDICATION.
Comments:		DUE TO A SLIP AND FALL ACCIDENT, I NEEDED TO GET BACK SURGERY FOR MY CONDITION. THE TYPE OF SURGERY I HAD WAS CALLED ANTERIOR CERVICAL DISKECTOMY AND FUSION FOR CERVICAL DISC DISPLACEMENT. THE DOCTOR PRESCRIBED OXYCODONE ALONG WITH NAPROXEN. I RARELY TOOK THE NAPROXEN BUT TOOK THE OXYCODONE FOUR TIMES A DAY FOR TWO MONTHS. AT THIS TIME, I STILL TAKE THE MEDICATION ONLY WHEN I FEEL I NEED IT - APPROXIMATELY ONCE OR TWICE A DAY.