Oxybutynin (Oxybutynin Chloride) - Summary

OXYBUTYNIN SUMMARY

Chemically, oxybutynin chloride is d,I (racemic) 4-diethylamino-2-butynyl phenylcyclohexylglycolate hydrochloride. The empirical formula of oxybutynin chloride is C₂₂H₃₁NO₃•HCl.

Oxybutynin Chloride Tablets are indicated for the relief of symptoms of bladder instability associated with voiding in patients with uninhibited neurogenic or reflex neurogenic bladder (i.e., urgency, frequency, urinary leakage, urge incontinence, dysuria).

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OXYBUTYNIN NEWS HIGHLIGHTS

Published Studies Related to Oxybutynin

Efficacy and safety of extended-release oxybutynin in combination with tamsulosin for treatment of lower urinary tract symptoms in men: randomized, double-blind, placebo-controlled study. [2008.09]

Intravesical oxybutynin for children with poorly compliant neurogenic bladder: a systematic review. [2008.09]

Intravesical Oxybutynin for Children With Poorly Compliant Neurogenic Bladder: A Systematic Review. [2008.07.17]

Randomized, placebo-controlled trial of the cognitive effect, safety, and tolerability of oral extended-release oxybutynin in cognitively impaired nursing home residents with urge urinary incontinence. [2008.05]

A prospective, randomized, double-blinded placebo-controlled comparison of extended release oxybutynin versus phenazopyridine for the management of postoperative ureteral stent discomfort. [2008.05]

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Clinical Trials Related to Oxybutynin

A Study Comparing the Efficacy and Safety of OROS® Oxybutynin to That of Ditropan® (Immediate-Release Oxybutynin) for the Treatment of Patients With Urge or Mixed Urinary Incontinence. [Completed]

Transdermal (TDS) Oxybutynin (Oxytrol(r)) in Overactive Bladder [Completed]

Efficacy and Safety of OROS Oybutynin and TTS Oxybutynin in Middle-Aged and Elderly Women With Urinary Incontinence [Completed]

Fasting Study of Oxybutynin Chloride ER Tablets 10 mg and Ditropan XL® Tablets 10 mg [Completed]

Food Study of Oxybutynin Chloride ER Tablets 10 mg and Ditropan XL® Tablets 10 mg [Completed]

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OXYBUTYNIN PATIENT REVIEWS / RATINGS / COMMENTS

Oxybutynin review by 49 year old female patient
		Rating
Overall rating:
Effectiveness:		Considerably Effective
Side effects:		Mild Side Effects
		Treatment Info
Condition / reason:		Spastic bladder
Dosage & duration:		10 mg tab taken once a day for the period of 2 years
Other conditions:		Multiple Sclerosis
Other drugs taken:		Wellbutrin 300 mg, Copaxone 20 mg, Adderall 20 mg
		Reported Results
Benefits:		Oxybutynin Chloride reduced my urinary urgency by lessening my bladder spasms, and reduced my urinary frequency, decreasing the number of times I needed to use the bathroom during the day. It also eliminated the need for me to have to get out of bed to void during night.
Side effects:		Dry mouth, constipation
Comments:		Take one tablet once a day.