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Oxistat (Oxiconazole Nitrate Topical) - Summary

 
 



OXISTAT SUMMARY

OXISTAT Cream and Lotion formulations contain the antifungal active compound oxiconazole nitrate. Both formulations are for topical dermatologic use only.

OXISTAT Cream and Lotion are indicated for the topical treatment of the following dermal infections: tinea pedis, tinea cruris, and tinea corporis due to Trichophyton rubrum, Trichophyton mentagrophytes, or Epidermophyton floccosum. OXISTAT Cream is indicated for the topical treatment of tinea (pityriasis) versicolor due to Malassezia furfur (see DOSAGE AND ADMINISTRATION and CLINICAL STUDIES).

OXISTAT Cream may be used in pediatric patients for tinea corporis, tinea cruris, tinea pedis, and tinea (pityriasis) versicolor; however, these indications for which OXISTAT Cream has been shown to be effective rarely occur in children below the age of 12.


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NEWS HIGHLIGHTS

Published Studies Related to Oxistat (Oxiconazole Topical)

[Oxiconazole cream versus ketoconazole cream. A prospective, randomized, double-blind, multicenter study in the treatment of inguinocrural dermatophytoses] [1996]
INTRODUCTION: The aim of this study was to compare oxiconazole, 1 p. 100 cream, with ketoconazole, 2 p... DISCUSSION: After 3 weeks of topical treatment oxiconazole has revealed itself to be as efficient as ketoconazole, but it seems more rapidly efficient and better tolerated than ketoconazole.

Oxiconazole nitrate lotion, 1 percent: an effective treatment for tinea pedis. [1994.07]
Four hundred and ten subjects were enrolled in a randomized, double-blind, parallel vehicle-controlled study to confirm the effectiveness and safety of topically applied oxiconazole nitrate (Oxistat) lotion, 1 percent, used once or twice daily in the treatment of tinea pedis..

One daily application of oxiconazole cream is sufficient for treating dermatomycoses. [1987]
A single daily application of oxiconazole cream was shown, in a double-blind, randomized, multicentric study, to be effective in treating various dermatomycoses as well as erythrasma. Tolerance was excellent and side effects were negligible..

Oxiconazole nitrate: pharmacology, efficacy, and safety of a new imidazole antifungal agent. [1991.01]
Oxiconazole nitrate (1%) cream became available in the United States in 1989 for the once-daily treatment of tinea pedis, tinea cruris, and tinea corporis... Once-daily use of oxiconazole cream could be valuable in patients with a history of noncompliance with multiple-daily regimens of other topical antifungal agents.

Clinical and experimental mycotic keratitis caused by Aspergillus terreus and the effect of subconjunctival oxiconazole treatment in the animal model. [1990.12]
Aspergillus terreus was isolated from a case of Keratomycosis. The patient, a 50 year old, female presented with a large corneal ulcer with hypopyon...

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Page last updated: 2006-01-31

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