Oxazepam (Oxazepam) - Indications and Dosage

INDICATIONS

Oxazepam is indicated for the management of anxiety disorders or for the short-term relief of the symptoms of anxiety. Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic.

Anxiety associated with depression is also responsive to oxazepam therapy.

This product has been found particularly useful in the management of anxiety, tension, agitation, and irritability in older patients.

Alcoholics with acute tremulousness, inebriation, or with anxiety associated with alcohol withdrawal are responsive to therapy.

The effectiveness of oxazepam in long-term use, that is, more than 4 months, has not been assessed by systematic clinical studies. The physician should reassess periodically the usefulness of the drug for the individual patient.

DOSAGE AND ADMINISTRATION

Because of the flexibility of this product and the range of emotional disturbances responsive to it, dosage should be individualized for maximum beneficial effects.

	Usual Dose
Mild-to-moderate anxiety, with associated tension, irritability, agitation, or related symptoms of functional origin or secondary to organic disease.	10 to 15 mg, 3 or 4 times daily
Severe anxiety syndromes, agitation, or anxiety associated with depression.	15 to 30 mg, 3 or 4 times daily
Older patients with anxiety, tension, irritability, and agitation.	Initial dosage: 10 mg, 3 times daily. If necessary, increase cautiously to 15 mg, 3 or 4 times daily.
Alcoholics with acute inebriation, tremulousness, or anxiety on withdrawal.	15 to 30 mg, 3 or 4 times daily

This product is not indicated in pediatric patients under 6 years of age. Absolute dosage for pediatric patients 6-12 years of age is not established.

HOW SUPPLIED

Oxazepam Capsules, USP are available as blue and white capsules filled with white powder, imprinted 4804, containing 10 mg of oxazepam, USP; as clear capsules filled with white powder, imprinted 4805, containing 15 mg of oxazepam, USP; and as orange and white capsules filled with white powder, imprinted 4806, containing 30 mg of oxazepam, USP. All strengths are packaged in bottles of 100, 500 and unit-dose boxes of 100 capsules.

PHARMACIST: Dispense in a well-closed container as defined in the USP. Use child-resistant closure (as required).

Store at 20°-25°C (68°-77°F) [See USP Controlled Room Temperature].