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Ovide (Malathion Topical) - Summary

 
 



OVIDE SUMMARY

OVIDE Lotion contains 0.005 g of malathion per mL in a vehicle of isopropyl alcohol (78%), terpineol, dipentene, and pine needle oil.

OVIDE Lotion is indicated for patients infected with Pediculus humanus capitis (head lice and their ova) of the scalp hair.


See all Ovide indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Ovide (Malathion Topical)

Healthcare providers do not fully understand cancer risk from CT scans
Source: Cancer / Oncology News From Medical News Today [2016.06.24]
Knowledge of radiation dose and associated risks varies among referring physicians, radiologists, and technicians, according to a new study in the Journal of Medical Imaging and Radiation Sciences.

Plant kingdom provides 2 new candidates for the war on antibiotic resistance
Source: Infectious Diseases / Bacteria / Viruses News From Medical News Today [2016.06.22]
Scientists have isolated peptides (strings of amino acids) with antibiotic effects on bacteria that spoil food and cause food poisoning, after turning to the plant kingdom for help in boosting our...

A novel therapy for genital herpes engages immune cells to provide significant patient benefits for at least a year
Source: Immune System / Vaccines News From Medical News Today [2016.06.21]
A phase II clinical trial demonstrated that a new type of treatment for genital herpes, an immunotherapy called GEN-003, may reduce the activity of the virus and the number of days with recurrent...

'Map' of teenage brain provides strong evidence of link between serious antisocial behaviour and brain development
Source: Psychology / Psychiatry News From Medical News Today [2016.06.16]
The brains of teenagers with serious antisocial behaviour problems differ significantly in structure to those of their peers, providing the clearest evidence to date that their behaviour stems from...

New research provides hope for patients with hard-to-treat breast cancer
Source: Breast Cancer News From Medical News Today [2016.06.13]
Cancer Research UK scientists have found a new way to slow the growth of the most aggressive type of breast cancer, according to research published in the journal Oncogene.

more news >>

Published Studies Related to Ovide (Malathion Topical)

Oral ivermectin for head lice: a comparison with 0.5 % topical malathion lotion. [2010.12]
BACKGROUND: Reports of treatment failure of head lice have become increasingly common. Oral ivermectin has been proposed as a potential alternative for the treatment of head lice infestation. The aim of this study was to compare the efficacy of oral ivermectin with topical malathion lotion in the treatment of head lice... CONCLUSIONS: Oral ivermectin is a promising effective approach for the treatment of head lice and could be an ideal substitute for conventional pediculicides. (c) The Author * Journal compilation (c) Blackwell Verlag GmbH, Berlin.

Oral ivermectin versus malathion lotion for difficult-to-treat head lice. [2010.03.11]
BACKGROUND: Head-lice infestation is prevalent worldwide, especially in children 3 to 11 years old. Topical insecticides (i.e., pyrethroids and malathion) used as a lotion, applied twice at an interval of 7 to 11 days, are typically used for treatment. Resistance of lice to insecticides, particularly pyrethroids, results in treatment failure. The efficacy of alternative agents is controversial... CONCLUSIONS: For difficult-to-treat head-lice infestation, oral ivermectin, given twice at a 7-day interval, had superior efficacy as compared with topical 0.5% malathion lotion, a finding that suggests that it could be an alternative treatment. (ClinicalTrials.gov number, NCT00819520.) 2010 Massachusetts Medical Society

Randomised, controlled, assessor blind trial comparing 4% dimeticone lotion with 0.5% malathion liquid for head louse infestation. [2007.11.07]
BACKGROUND: Malathion 0.5% has been the most prescribed pediculicide in the United Kingdom for around 10 years, and is widely used in Europe and North America...

Efficacy of a reduced application time of Ovide lotion (0.5% malathion) compared to Nix creme rinse (1% permethrin) for the treatment of head lice. [2004.11]
Our objective was to conduct a randomized, investigator-blinded evaluation of the pediculicidal and ovicidal activity of a reduced application time (20 minutes) of Ovide (0.5% malathion) compared to Nix (1% permethrin) in a south Florida population infested with Pediculus humanus capitis...

Oral ivermectin for head lice: a comparison with 0.5 % topical malathion lotion. [2010.08.13]
Summary Background: Reports of treatment failure of head lice have become increasingly common...

more studies >>

Clinical Trials Related to Ovide (Malathion Topical)

Pharmacokinetics of Malathion Gel 0.5% and Malathion 0.5% Lotion (Ovide) in Patients With Head Lice [Completed]
In this study, 24 adult patients with head lice will be treated with a topical malathion head lice treatment; 12 patients will be treated with a novel product, Malathion Gel, 0. 5%, and other 12 patients will be treated with Ovide Lotion 0. 5% marketed by Taro Pharmaceuticals USA, Inc. The primary objective of this study is to compare the blood level exposure of Malathion 0. 5% Gel to that of the OVIDE Lotion 0. 5%.

Efficacy, Safety and Tolerability of a Novel Malathion Formulation in Patients 2 Years and Older With Head Lice [Completed]
In this study, Malathion Gel 0. 5% will be compared to Nix (permethrin 1%) as a treatment for head lice in patients 2 years of age and older. Malathion Gel 0. 5% is a new formulation of an established head lice treatment. The new formulation has been evaluated in 2 previous studies of patients 2 years of age and older.

Safety and Efficacy of a Novel Malathion Formulation in the Treatment of Head Lice [Completed]
Current treatments for head lice include over-the-counter products such as permethrin and prescription products such as OVIDE (malathion 0. 5%) lotion. In a previous phase II study, a novel, easy-to-use malathion 0. 5% formulation was found to be a safe treatment for head lice. The current study will compare the efficacy and safety of this novel formulation of malathion with OVIDE and with an over-the-counter permethrin product.

Efficacy, Safety and Tolerability of a Novel Malathion Formulation in Patients 2 Years and Older With Head Lice [Completed]
In this study, Malathion Gel 0. 5% will be compared to Nix (permethrin 1%) as a treatment for head lice in patients 2 years of age and older. Malathion Gel 0. 5% is a new formulation of an established head lice treatment. The new formulation has been evaluated in 2 previous studies of patients 2 years of age and older.

Ivermectin in the Treatment of Head Lice [Completed]
The purpose of this study is to compare 2 single doses of ivermectin as tablets with 2 single applications of malathion 0. 5% lotion (Days 1 and 8) in clearing head lice, in patients who have recently used standard head lice treatments without success.

more trials >>

Reports of Suspected Ovide (Malathion Topical) Side Effects

Application Site Burn (3)Burns Second Degree (3)Fall (2)Loss of Consciousness (2)Skin Infection (2)Accidental Exposure (2)Chemical Injury (2)Muscle Atrophy (1)Peroneal Nerve Palsy (1)Oedema Peripheral (1)more >>


Page last updated: 2016-06-24

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