Published Studies Related to Oruvail Extended-Release (Ketoprofen)
Comparing the efficacy of intravenous tenoxicam, lornoxicam, and dexketoprofen
trometamol for the treatment of renal colic. 
dexketoprofen trometamol-for the treatment of patients with renal colic... CONCLUSIONS: Intravenous tenoxicam, lornoxicam, and dexketoprofen are all
Postoperative analgesic efficacy of intravenous dexketoprofen in lumbar disc surgery. [2011.07]
BACKGROUND: We investigated the postoperative analgesic efficacy and effect on total tramadol consumption of intravenous dexketoprofen trometamol, a new nonsteroidal anti-inflammatory drug, in patients that had undergone lumbar disc surgery... CONCLUSION: We found that dexketoprofen was an effective analgesic for postdiscectomy pain when used alone or in addition to opioids. It is easy to administer and decreases tramadol consumption and opioid-related side effects.
Clinical evaluation of meloxicam versus ketoprofen in cats suffering from painful acute locomotor disorders. [2011.04]
The aim of this study was to evaluate the efficacy and palatability of meloxicam 0.5mg/ml oral suspension, compared to ketoprofen tablets in cats suffering from painful acute locomotor disorders. This single blinded, positively-controlled, randomised, multicentre trial involved 121 client owned cats...
[Pre-emptive ketoprofen for postoperative pain relief after urologic surgery]. [2011.01]
BACKGROUND: Effective multimodal postoperative analgesia is one of determinants of patient satisfaction after successful surgery. Following the recommendations of non-steroidal antiinflammatory agents (NSAIDs) for pre-emptive analgesia, we assessed the efficacy of ketoprofen administered before urological surgery... CONCLUSION: Pre-emptive analgesia with intravenous ketoprofen was ineffective in patients undergoing urological surgery.
[The effects of preemptive dexketoprofen use on postoperative pain relief and tramadol consumption]. [2011.01]
OBJECTIVES: In this study, the efficacy of preemptive dexketoprofen usage on postoperative pain relief and tramadol consumption was evaluated... CONCLUSION: Preemptive use of dexketoprofen reduced postoperative tramadol consumption and incidence of adverse events.
Clinical Trials Related to Oruvail Extended-Release (Ketoprofen)
Trial on Metoclopramide and Ketoprofen in Acute Migraine of Childhood [Not yet recruiting]
This is a Randomized double blind trial with the aim to estimate the effectiveness of 3
therapeutic regimes per os on migraine pain:
- metoclopramide 0,15 mg/kg + placebo
- metoclopramide 0,15 mg/Kg + ketoprofen 1 mg/kg
- ketoprofen 1 mg/Kg + placebo
Intensity of pain will be measured with linear 1-10 scale or analogic McGrath type scale
every 20 min.
The main objective is the evaluation of healing times from pain in the 3 groups
Study to Assess the Efficacy and Safety of Ibuprofen 50 mg/g Gel Compared to Profenid 25mg/g Gel [Not yet recruiting]
The aim of this study is to determine that ibuprofen 50mg/g gel is effective and safety
treating patients with muscle aches, joint pains or due to sprains, bruises, tendinitis or
myofascial compared to Profenid 25mg/g gel.
Evaluation of Inflammatory Symptoms Reduction With Amoxicillin + Ketoprofen in Acute Pharyngeal- Tonsillitis in Pediatric Patients [Recruiting]
The purpose of this study is to evaluate the inflammatory symptoms and signs (hyperemia,
edema and pain) reduction after 24 hours of treatment with ketoprofen drops when associated
Topical Intra-Oral Ketoprofen for Migraine Prevention [Recruiting]
Intra-Oral Topical Ketoprofen gel, applied to a branch of the trigeminal nerve, has been
shown to prevent migraines when used once daily for 3 months in open label studies. This is
a randomized, double-blind, placebo controlled phase III prevention trial to determine
safety and efficacy.
Study of Non Inferiority Bi-Profenid® 200mg Versus Bi-Profenid® 300mg Among Patients Presenting of the Post-Traumatic or Rheumatologic Acute Affections of the Locomotor Apparatus (BIPROPAIN) [Recruiting]
To demonstrate the non-inferiority of Bi-Profenid 100 mg x 2 day versus Bi-Profenid 150 mg x
2 day in patients presenting with pain related to closed, benign, acute post-traumatic
conditions of the motor system or acute, non-infectious rheumatologic conditions, by
comparing, on the one hand, changes in resting pain intensity over the entire day, measured
at the end of the day using a numeric scale (NS), over 5 days and, on the other hand, total
intake over 5 days of concomitant analgesics.
- To describe concomitant analgesic treatments
- To describe the time between baseline and use of a step I, II or III analgesic
- To evaluate patients pain relief using a Likert 4-class scale (complete or substantial
relief, moderate relief slight relief and absence of relief) at D5
- To evaluate changes in intensity of pain when moving, over the entire day, measured at
the end of the day using a numeric scale, over 5 days
- To evaluate the patients overall satisfaction at the end of treatment using a 4-point
Simple Verbal Scale (SVS) (very satisfied, somewhat satisfied, somewhat unsatisfied,
- To evaluate the patients overall satisfaction at the end of the study using a 4-point
Simple Verbal Scale (EVS) (very satisfied, somewhat satisfied, somewhat unsatisfied,
- To compare the safety of the two treatments