News related to Orencia (Abatacept) and/or conditions it is approved for
Abatacept, Adalimumab Equal Head-to-Head for RA at 2 Years
Source: Medscape Medical News Headlines [2013.06.14]
The first head-to-head comparison of 2 biologics showed comparable efficacy for the 2 commonly used drugs.
Medscape Medical News
In Rheumatoid Arthritis, Abatacept As Effective As Adalimumab, With Fewer Injection Site Reactions
Source: Health News from Medical News Today [2013.06.14]
Data from AMPLE presented at EULAR 2013, the Annual Congress of the European League Against Rheumatism, demonstrate comparable efficacy and similar safety profiles between subcutaneous abatacept (ABA) and adalimumab (ADA). AMPLE, the first two-year head-to-head biologics trial, was comprised of 646 biologic-naïve patients with active rheumatoid arthritis (RA) equally randomised to either ABA or ADA, with a stable dose of methotrexate (MTX). 79.2% (252 of 318) ABA patients and 74.7% (245 of 328) ADA patients completed the trial...
Drug Discontinuations Rampant in Rheumatoid Arthritis
Source: Medscape Medical News Headlines [2013.06.15]
In the modern era of biologics, up to one third of patients with rheumatoid arthritis still discontinue therapy within a year, most often because of lack of efficacy.
Medscape Medical News
The Impact Of Rheumatoid Arthritis On Joint Replacement Surgery Outcomes
Source: Health News from Medical News Today [2013.06.15]
Two new studies by researchers at Hospital for Special Surgery have shed light on joint replacement outcomes in patients with rheumatoid arthritis (RA). One study overturns the common belief that RA patients have worse outcomes after a total knee replacement (TKR) than patients who undergo the operation for osteoarthritis. The other study demonstrates that RA patients who undergo a total hip replacement were as likely to have significant improvements in function and pain as patients with osteoarthritis (OA), even though they did not do as well...
Roche's RoActemra® (Tocilizumab) Shows Long-Term Efficacy In Monotherapy And Also Benefits In Early Rheumatoid Arthritis
Source: Health News from Medical News Today [2013.06.14]
Roche (SIX: RO, ROG; OTCQX: RHHBY) have announced data from two phase III studies using RoActemra in patients with rheumatoid arthritis (RA): the long-term extension (LTE) follow up of the AMBITION study demonstrated long-term efficacy of RoActemra without methotrexate (MTX); and the FUNCTION study showed the clinical benefits of the medicine, alone or in combination with MTX, when used to treat patients with early RA.1,2 These studies are being presented at the 2013 European League Against Rheumatism (EULAR) Congress...
Joint Damage Successfully Identified In Rheumatoid Arthritis
Source: Health News from Medical News Today [2013.06.14]
A new study presented at EULAR 2013, the Annual Congress of the European League Against Rheumatism, demonstrates the efficacy of the ARASHI method at evaluating radiographic (X-ray) joint damage in RA. The study validated the use of ARASHI to assess joint damage in RA, and clarified the pattern of progression of damage during two-year TNF-blocking therapies. In addition to concluding the success of the scoring method, the data also showed that hip and knee joints with pre-existing damage were predisposed to continue destruction, even during two-year treatment with TNF-blocking therapies...
Standard Rheumatoid Arthritis Therapy as Good as Costlier Newcomer: Study
Source: MedicineNet Arthritis Specialty [2013.06.12]
Title: Standard Rheumatoid Arthritis Therapy as Good as Costlier Newcomer: Study
Category: Health News
Created: 6/11/2013 8:36:00 PM
Last Editorial Review: 6/12/2013 12:00:00 AM
Choosing a Biologic in Rheumatoid Arthritis
Source: Medscape Pharmacists Headlines [2013.06.11]
Dr. Kay summarizes recent comparative effectiveness trials of biologic therapy for RA.
Medscape Rheumatology
Medication Compliance In Rheumatoid Arthritis
Source: Arthritis / Rheumatology News From Medical News Today [2013.06.03]
A new study conducted in an ethnically diverse and predominantly low income population found that only one-fifth of rheumatoid arthritis (RA) patients had an overall adherence rate to prescribed oral medications at 80% or greater...
In The Most Severe Form Of Rheumatoid Arthritis, Enzyme-Activating Antibodies Identified As A Marker
Source: Arthritis / Rheumatology News From Medical News Today [2013.05.25]
In a series of lab experiments designed to unravel the workings of a key enzyme widely considered a possible trigger of rheumatoid arthritis, researchers at Johns Hopkins have found that in the most severe cases of the disease, the immune system makes a unique subset of antibodies that have a disease-promoting role...
Fat Triggers Rheumatoid Arthritis: Discovery Paves Way For New Gene Therapies, Treatments
Source: Arthritis / Rheumatology News From Medical News Today [2013.05.13]
Scientists have discovered that fat cells in the knee secrete a protein linked to arthritis, a finding that paves the way for new gene therapies that could offer relief and mobility to millions worldwide. ar "We found that fat in the knee joints secretes a protein called pro-factor D which gives rise to another protein known as factor D that is linked to arthritis," said Nirmal Banda, Ph.D...
Women Who Smoke May Have Higher Risk for Rheumatoid Arthritis
Source: MedicineNet Rheumatoid Arthritis Specialty [2013.04.29]
Title: Women Who Smoke May Have Higher Risk for Rheumatoid Arthritis
Category: Health News
Created: 4/26/2013 12:35:00 PM
Last Editorial Review: 4/29/2013 12:00:00 AM
Medications Used To Treat Rheumatoid Arthritis May Affect Abortion Rate In Women
Source: Abortion News From Medical News Today [2013.04.16]
A new study published in the American College of Rheumatology (ACR) journal, Arthritis Care & Research, reveals that women with rheumatoid arthritis (RA) who were on methotrexate (MTX), a drug commonly used to reduce inflammation caused by RA, had lower rates of induced abortions compared to women with RA who were not exposed to the medication...
Rheumatoid Arthritis
Source: MedicineNet Amyloidosis Specialty [2013.04.16]
Title: Rheumatoid Arthritis
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 4/16/2013 12:00:00 AM
Salty Diet Might Help Trigger MS, Rheumatoid Arthritis
Source: MedicineNet Ankylosing Spondylitis Specialty [2013.03.07]
Title: Salty Diet Might Help Trigger MS, Rheumatoid Arthritis
Category: Health News
Created: 3/6/2013 2:35:00 PM
Last Editorial Review: 3/7/2013 12:00:00 AM
Newer Rheumatoid Arthritis Drugs Don't Seem to Increase Risk of Shingles
Source: MedicineNet Shingles Specialty [2013.03.06]
Title: Newer Rheumatoid Arthritis Drugs Don't Seem to Increase Risk of Shingles
Category: Health News
Created: 3/5/2013 4:36:00 PM
Last Editorial Review: 3/6/2013 12:00:00 AM
Myeloma, Lupus, Rheumatoid Arthritis Patients May One Day Benefit From Research On Immune Cell 'Survival' Gene
Source: Lupus News From Medical News Today [2013.02.06]
Scientists have identified the gene essential for survival of antibody-producing cells, a finding that could lead to better treatments for diseases where these cells are out of control, such as myeloma and chronic immune disorders...
Aging Overweight Males At Increased Risk For Gout, Rheumatoid Arthritis
Source: Gout News From Medical News Today [2012.11.13]
Refuting a belief long held by many physicians, a Mayo Clinic study found that rheumatoid arthritis patients also can get gout. The research is among several studies Mayo Clinic presented at the American College of Rheumatology annual meeting in Washington...
The Impact Of Rheumatoid Arthritis And Lupus On Joint Replacement Surgery Outcomes
Source: Lupus News From Medical News Today [2012.11.13]
Two new studies by researchers at Hospital for Special Surgery have overturned common beliefs about joint replacement in patients with lupus and rheumatoid arthritis (RA). In one study, researchers demonstrated that RA patients who undergo a knee replacement can expect outcomes that are similar to individuals undergoing the operation for osteoarthritis...
Newer Rheumatoid Arthritis Drugs Don't Raise Cancer Risk: Study
Source: MedicineNet adalimumab Specialty [2012.09.07]
Title: Newer Rheumatoid Arthritis Drugs Don't Raise Cancer Risk: Study
Category: Health News
Created: 9/6/2012 4:06:00 PM
Last Editorial Review: 9/7/2012 12:00:00 AM
Elevated Antibody Levels May Predict Rheumatoid Arthritis Risk
Source: MedicineNet Rheumatoid Factor Specialty [2012.09.07]
Title: Elevated Antibody Levels May Predict Rheumatoid Arthritis Risk
Category: Health News
Created: 9/7/2012 10:05:00 AM
Last Editorial Review: 9/7/2012 12:00:00 AM
Study Compares Safety of 'Biologic' Meds for Rheumatoid Arthritis
Source: MedicineNet adalimumab Specialty [2012.08.08]
Title: Study Compares Safety of 'Biologic' Meds for Rheumatoid Arthritis
Category: Health News
Created: 8/8/2012 10:05:00 AM
Last Editorial Review: 8/8/2012 12:00:00 AM
No Dip in Cancer Screening for Rheumatoid Arthritis Patients
Source: MedicineNet Cancer Detection Specialty [2012.07.10]
Title: No Dip in Cancer Screening for Rheumatoid Arthritis Patients
Category: Health News
Created: 7/10/2012 10:05:00 AM
Last Editorial Review: 7/10/2012 12:00:00 AM
Yoga May Improve Symptoms of Rheumatoid Arthritis
Source: MedicineNet Juvenile Arthritis Specialty [2012.05.25]
Title: Yoga May Improve Symptoms of Rheumatoid Arthritis
Category: Health News
Created: 5/25/2012 11:00:00 AM
Last Editorial Review: 5/25/2012 12:00:00 AM
Rheumatoid Arthritis - When Do I Call the Doctor?
Source: MedicineNet hydroxychloroquine Specialty [2012.01.31]
Title: Rheumatoid Arthritis - When Do I Call the Doctor?
Category: Doctor's Views
Created: 7/7/2001 12:46:00 PM
Last Editorial Review: 1/31/2012 12:00:00 AM
Rheumatoid Arthritis: Test Your Arthritis IQ
Source: MedicineNet anakinra Specialty [2012.01.18]
Title: Rheumatoid Arthritis: Test Your Arthritis IQ
Category: MedicineNet Quiz
Created: 1/31/2011 5:38:00 PM
Last Editorial Review: 1/18/2012 1:06:51 PM
Patient Story: Rheumatoid Arthritis Symptoms
Source: MedicineNet Rheumatoid Factor Specialty [2012.01.18]
Title: Patient Story: Rheumatoid Arthritis Symptoms
Category: Doctor's Views
Created: 1/18/2012 4:28:00 PM
Last Editorial Review: 1/18/2012 12:00:00 AM
Rheumatoid Arthritis (RA) Pictures Slideshow
Source: MedicineNet Baker Cyst Specialty [2011.09.26]
Title: Rheumatoid Arthritis (RA) Pictures Slideshow
Category: Slideshows
Created: 11/10/2008 12:00:00 AM
Last Editorial Review: 9/26/2011 12:00:00 AM
Rheumatoid Arthritis Pictures Slideshow
Source: MedicineNet Elbow Bursitis Specialty [2008.11.13]
Title: Rheumatoid Arthritis Pictures Slideshow
Category: Slideshows
Created: 11/10/2008
Last Editorial Review: 11/13/2008
Juvenile Arthritis (Juvenile Rheumatoid Arthritis)
Source: MedicineNet Citrulline Antibody Specialty [2008.03.25]
Title: Juvenile Arthritis (Juvenile Rheumatoid Arthritis)
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 3/25/2008 12:00:00 AM
The impact of smoking and genes on rheumatoid arthritis
Source: The Doctors Lounge - Orthopedics
New insight into the autoimmune triggers for rheumatoid arthritis among smokers with shared epitope genes.
The impact of smoking and genes on rheumatoid arthritis
Source: The Doctors Lounge - Rheumatology
New insight into the autoimmune triggers for rheumatoid arthritis among smokers with shared epitope genes.
Adalimumab plus methotrexate effective for rheumatoid arthritis
Source: The Doctors Lounge - Rheumatology
Adalimumab and methotrexate is about five times more effective than methotrexate alone, according to a new systematic review of studies.
NSAID Use Raises Heart Risk in Arthritis (CME/CE)
Source: MedPageToday.com - medical news plus CME for physicians [2013.06.15]
MADRID (MedPage Today) -- Patients with rheumatoid arthritis and other inflammatory musculoskeletal diseases continue to be treated with nonsteroidal anti-inflammatory drugs, even with their high risk for ischemic heart disease, a researcher said here.
Depression Key Reason to Stop Work with RA (CME/CE)
Source: MedPageToday.com - medical news plus CME for physicians [2013.06.14]
MADRID (MedPage Today) -- Depression was the strongest predictor of the decision by rheumatoid arthritis patients to apply for disability leave from work within a year of disease onset, a researcher said here.
No Long-Term Adherence for Biologics in RA? (CME/CE)
Source: MedPageToday.com - medical news plus CME for physicians [2013.06.14]
MADRID (MedPage Today) -- Despite the many biologics now available and the hope of more individualized therapy, half of U.S. patients with rheumatoid arthritis stopped these meds within 2 years, a large database analysis found.
Long-Term Efficacy And Safety Profile Of The Anti-TNF Golimumab Confirmed
Source: Arthritis / Rheumatology News From Medical News Today [2013.06.13]
MSD have announced that five-year data from pivotal Phase 3 clinical studies demonstrate that once-monthly, subcutaneous (SC) injections of Simponi® (golimumab) provided sustained improvements in the signs and symptoms of patients with both active ankylosing spondylitis (AS) and moderate to severe, active rheumatoid arthritis (RA) over five years...
Lilly says arthritis pill effective in mid-stage study
Source: Yahoo! Health News [2013.06.13]
(Reuters) - Eli Lilly and Co and Incyte Corp said their experimental drug was effective in reducing painful symptoms associated with rheumatoid arthritis after 52 weeks of treatment. The drug, baricitinib, is part of a new family of medicines call...
Drug Adherence Falters in RA Patients (CME/CE)
Source: MedPage Today Rheumatology [2013.05.31]
(MedPage Today) -- Many patients with rheumatoid arthritis (RA) don't take their oral medications as prescribed, which can have clinical consequences, researchers found.
Early Treatment Start Key to RA Remission (CME/CE)
Source: MedPage Today Rheumatology [2013.05.30]
(MedPage Today) -- Initiating aggressive treatment within 3 months of symptom onset was crucial to patients with new-onset rheumatoid arthritis achieving remission, a prospective study confirmed.
Link Between Immune Cell Death Defects And Autoimmune Diseases
Source: Lupus News From Medical News Today [2013.01.25]
Melbourne researchers have discovered that the death of immune system cells is an important safeguard against the development of diseases such as type 1 diabetes, rheumatoid arthritis and lupus, which occur when the immune system attacks the body's own tissues...
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