ADVERSE REACTIONS
| NOTE: THE SUSTAINED RELEASE OF MORPHINE FROM ORAMORPH SR SHOULD BE TAKEN INTO CONSIDERATION IN THE EVENT OF OCCURRING ADVERSE REACTIONS. |
Adverse reactions caused by morphine are essentially those observed with other opioid analgesics. They include the following major hazards: respiratory depression, and less frequently, circulatory depression, apnea, shock and cardiac arrest secondary to respiratory and/or circulatory depression.
Most Frequently Observed Reactions:
Constipation, nausea, vomiting, lightheadedness, dizziness, sedation, dysphoria, euphoria, and sweating. Some of these effects seem to be more prominent in ambulatory patients and in those not experiencing severe pain. Some adverse reactions in ambulatory patients may be alleviated if the patient is in a supine position.
Less Frequently Observed Reactions:
Body as a Whole: Edema, antidiuretic effect, chills, muscle tremor, muscle rigidity.
Cardiovascular: Flushing of the face, tachycardia, bradycardia, palpitation, faintness, syncope, hypotension, hypertension.
Gastrointestinal: Dry mouth, biliary tract spasm, laryngospasm, anorexia, diarrhea, cramps, taste alterations.
Genitourinary: Urine retention or hesitance, reduced libido and/or potency.
Nervous System: Weakness, headache, agitation, tremor, uncoordinated muscle movements, seizure, paresthesia, alterations of mood (nervousness, apprehension, depression, floating feelings), dreams, transient hallucination and disorientation, visual disturbances, insomnia, increased intracranial pressure.
Skin: Pruritus, urticaria and other skin rashes.
Special Senses: Blurred vision, nystagmus, diplopia, miosis.
|
REPORTS OF SIDE EFFECTS / ADVERSE REACTIONS RELATED TO ORAMORPH SR
Below is a sample of reports where side effects / adverse reactions may be related to Oramorph SR. The information is not vetted and should not be cosidered as verified clinical evidence.
Possible Oramorph SR side effects / adverse reactions in 62 year old female
Reported by a physician from United Kingdom on 2007-01-26
Patient: 62 year old female
Reactions: Overdose, Drug Administration Error
Adverse event resulted in: death
Suspect drug(s):
Oramorph SR
Dosage: 100mg administered
Indication: Lung Neoplasm Malignant
MST
Indication: Lung Neoplasm Malignant
Possible Oramorph SR side effects / adverse reactions in 84 year old female
Reported by a health professional (non-physician/pharmacist) on 2007-03-07
Patient: 84 year old female
Reactions: Incorrect Route of Drug Administration, Injection Site Pain
Suspect drug(s):
Oramorph SR
Possible Oramorph SR side effects / adverse reactions in 74 year old male
Reported by a physician on 2007-03-15
Patient: 74 year old male
Reactions: Confusional State, Emotional Distress, Fatigue, Dizziness, Depressed Level of Consciousness, Memory Impairment, Hallucination, Feeling Abnormal
Suspect drug(s):
Oramorph SR
Lyrica
Administration route: Oral
Indication: Neuralgia
Other drugs received by patient: Acetylsalicylic Acid SRT; Allopurinol; Aspirin; Carbocisteine; Furosemide; Oxygen; Prednisolone; Quinine Sulfate; Salbutamol; Slozem
|
