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Oramorph SR (Morphine Sulfate) - Summary

 
 



ORAMORPH SR SUMMARY

ORAMORPH® SR
(MORPHINE SULFATE)
Sustained Release Tablets
15 mg, 30 mg, 60 mg, 100 mg

Each tablet for oral administration contains morphine sulfate.....15 mg, 30 mg, 60 mg, or 100 mg in a tablet that provides for sustained release of the medication.

ORAMORPH SR is indicated for the relief of pain in patients who require opioid analgesics for more than a few days.


See all Oramorph SR indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Oramorph SR (Morphine)

The Myth of Morphine Equivalent Daily Dosage
Source: Medscape Anesthesiology Headlines [2016.05.24]
A new study suggests that a commonly used means of dosing opioid analgesics is flawed.
Medscape Neurology

Friends better than morphine: Larger social networks release more pain-killing endorphin
Source: Pain / Anesthetics News From Medical News Today [2016.04.28]
People with more friends have higher pain tolerance, Oxford University researchers have found.

Medical News Today: Can Weight Loss Help Ease Knee Pain?
Source: Featured Health News from Medical News Today [2016.05.28]
Learn all about how weight loss can ease knee pain linked with osteoarthritis. This article also looks at the effect of obesity on osteoarthritis.

Can Weight Loss Help Ease Knee Pain?
Source: Arthritis / Rheumatology News From Medical News Today [2016.05.28]
Learn all about how weight loss can ease knee pain linked with osteoarthritis. This article also looks at the effect of obesity on osteoarthritis.

Tools Refined to Assess Catastrophizing in Chronic Pain
Source: Medscape Anesthesiology Headlines [2016.05.27]
The response to a key catastrophizing measure can predict the risk for opioid misuse, a new study suggests.
Medscape Medical News

more news >>

Published Studies Related to Oramorph SR (Morphine)

Influence of Morphine on Pharmacokinetics and Pharmacodynamics of Ticagrelor in Patients with Acute Myocardial Infarction (IMPRESSION): study protocol for a randomized controlled trial. [2015]
BACKGROUND: Ticagrelor is an oral platelet P2Y12 receptor antagonist which is recommended for patients suffering from myocardial infarction, both with and without persistent ST segment elevation... DISCUSSION: This study is expected to provide essential evidence-based data on the impact of morphine on the absorption of ticagrelor in patients with myocardial infarction as well as to shed some light on the suspected connection between morphine use and antiplatelet activity of ticagrelor in the same group of patients.

Efficacy and safety of sublingual fentanyl orally disintegrating tablet at doses determined from oral morphine rescue doses in the treatment of breakthrough cancer pain. [2015]
evaluate the efficacy and safety of sublingual fentanyl tablet... CONCLUSIONS: Patients treated with strong opioid analgesics at fixed intervals

Evaluation of a single-dose, extended-release epidural morphine formulation for pain control after lumbar spine surgery. [2014]
DepoDur, an extended-release epidural morphine, has been used effectively for postoperative pain control following many orthopaedic and general surgery procedures and has provided prolonged analgesia when compared with Duramorph. The goal of this article was to compare the safety and analgesic efficacy of DepoDur versus Duramorph after lumbar spine surgery...

Morphine decreases clopidogrel concentrations and effects: a randomized, double-blind, placebo-controlled trial. [2014]
effects on platelets... CONCLUSIONS: Morphine delays clopidogrel absorption, decreases plasma levels of

Transversus abdominis plane block versus perioperative intravenous lidocaine versus patient-controlled intravenous morphine for postoperative pain control after laparoscopic colorectal surgery: study protocol for a prospective, randomized, double-blind controlled clinical trial. [2014]
BACKGROUND: Despite the laparoscopic approach becoming the standard in colorectal surgery, postoperative pain management for minimally invasive surgery is still mainly based on strategies that have been established for open surgical procedures... DISCUSSION: Recognizing the importance of a multimodal approach for perioperative pain management, we aim to investigate whether a transversus abdominis plane block delivers superior pain control in comparison to perioperative intravenous lidocaine and patient-controlled intravenous analgesia with morphine alone.

more studies >>

Clinical Trials Related to Oramorph SR (Morphine)

Patients-Controlled Epidural Analgesia After Gastric Bypass for Morbid Obesity Using Morphine-Levobupivacaine Regimens [Completed]
Adequate postoperative analgesia can facilitate recovery following gastric bypass surgery

for morbid obesity. The efficacy and safety of intravenous patient - controlled analgesia

has been studied, but up to date no data are available concerning the use of thoracic epidural patient-controlled analgesia regarding the use of levobupivacaine combined with morphine in morbidly obese patients. The investigators' aim in this prospective, randomized, double-blinded study was to compare the analgesic effectiveness, the dose requirements and side effects of thoracic epidural patient controlled analgesia 0. 1% and 0. 2% levobupivacaine combined with a continuous epidural administration of morphine, with or without a loading dose, after open gastric bypass for morbid obesity.

The Median Effective Dose (ED50) of Paracetamol and Morphine : A Study of Interaction Study [Completed]
The aim of our study is to define the median effective analgesic doses (ED50) of paracetamol, morphine, and their combination and determination the nature of their interaction administered IV for postoperative pain after moderate painful surgery using up-and-down and isobolographic methods.

A Comparison of Morphine and Morphine Plus Dexmedetomidine in Chronic Cancer Pain [Recruiting]
The purpose of this study is to determine whether dexmedetomidine added to morphine is effective in the treatment of chronic cancer pain.

Ketamine Associated With Morphine PCA After Total Hip Arthroplasty [Completed]
Ketamine (an analgesic drug often associated with morphine in the treatment of Opioid Induced Hyperalgesia) is often mixed in Morphine PCA syringe. We make the hypothesis that ketamine administrated separately via a continuous infusion, could induced a better analgesic effect. We will perform a randomised double blind study to determine the best infusion mode of intravenous ketamine, associated with morphine in PCA syringe or alone in continuous infusion.

Continuous Pre-uterine Wound Infiltration Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean Section [Recruiting]
The cesarean section is considered as a painful surgery during the post operative period. Mothers may need to move immediately after the surgery to take care of their babies. This may increase the risk of major pain and chronic pain. Thus, excellent postoperative analgesia is required so that mothers do not experience pain in caring for their baby. Currently, several techniques have been developed to manage postoperative pain related to c-section scar such as intrathecal morphine during spinal anesthesia or continuous pre-peritoneal wound infiltration. The comparison between anesthetic techniques has never been performed and it is still not know if the combination of intrathecal morphine plus continuous pre-peritoneal wound infiltration provide a synergistic or additional effect on pain relief.

more trials >>

Reports of Suspected Oramorph SR (Morphine) Side Effects

Abdominal Pain (26)Cardio-Respiratory Arrest (26)Completed Suicide (6)Respiratory Depression (5)Depression (5)Multiple Drug Overdose (5)Renal Failure Acute (5)Intentional Drug Misuse (4)Lethargy (4)Respiratory Arrest (4)more >>


Page last updated: 2016-05-28

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