Media Articles Related to Optison (Albumin Human)
The Biology of Borderline (and a Diagnostic Tip)
Source: Medscape NeurologyHeadlines [2015.03.23]
Dr Derick Vergne on the challenges of diagnosing borderline personality disorder and some of the unique factors that contribute to its pathophysiology.
Study examines diagnostic accuracy of pathologists interpreting breast biopsies
Source: Breast Cancer News From Medical News Today [2015.03.20]
In a study in which pathologists provided diagnostic interpretation of breast biopsy slides, overall agreement between the individual pathologists' interpretations and that of an expert consensus...
Comparing the diagnostic criteria for the DSM-5 and ICD-10
Source: Alcohol / Addiction / Illegal Drugs News From Medical News Today [2015.03.19]
Both the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5), and the International Statistical Classification of Diseases and Related Health Problems, 10th Edition (ICD-10)...
ACC: CT No Better Than Stress Test as Chest Pain Diagnostic (CME/CE)
Source: MedPage Today Radiology [2015.03.14]
(MedPage Today) -- No difference in outcomes but more radiation with CT angiography.
Cochrane Review of effectiveness of point of care diagnostics for schistosomiasis
Source: Tropical Diseases News From Medical News Today [2015.03.13]
Researchers from the Cochrane Infectious Disease Group, hosted at LSTM, have conducted an independent review to assess how well point of care tests detect Schistosoma infections in people living in...
Published Studies Related to Optison (Albumin Human)
Effects of combined lipoic acid and pyridoxine on albuminuria, advanced glycation
end-products, and blood pressure in diabetic nephropathy. 
This study was designed to investigate the effects of combined administration of
lipoic acid and pyridoxine on albuminuria, oxidative stress, blood pressure,
serum advanced glycation end-products, nitric oxide (NO), and endothelin-1 in
patients with diabetic nephropathy.
High-dose albumin treatment for acute ischaemic stroke (ALIAS) Part 2: a
randomised, double-blind, phase 3, placebo-controlled trial. 
proportion of patients with a favourable outcome... INTERPRETATION: Our findings show no clinical benefit of 25% albumin in patients
Albumin resuscitation for traumatic brain injury: is intracranial hypertension
the cause of increased mortality? 
Mortality is higher in patients with traumatic brain injury (TBI) resuscitated
with albumin compared with saline, but the mechanism for increased mortality is
Associations of albuminuria in patients with chronic heart failure: findings in the ALiskiren Observation of heart Failure Treatment study. [2011.07]
CONCLUSIONS: Increased UACR is common in patients with heart failure, including non-diabetics. Urinary albumin creatinine ratio is independently associated with HbA1c and NT-proBNP, even in non-diabetic patients.
Long-term effects of fosinopril and pravastatin on cardiovascular events in subjects with microalbuminuria:Ten years of follow-up of Prevention of Renal and Vascular End-stage Disease Intervention Trial (PREVEND IT). [2011.06]
BACKGROUND: The PREVEND IT investigated whether treatment targeted at lowering urinary albumin excretion (UAE) would reduce adverse cardiovascular events. We obtained extended follow-up data to approximately 10 years to investigate the long-term effects of fosinopril 20 mg and pravastatin 40 mg on cardiovascular outcomes in subjects with UAE >15 mg per 24 hours... CONCLUSIONS: Elevated UAE is associated with increased cardiovascular mortality and morbidity after 9.5 years of follow-up, with a doubling of the risk if the UAE is >50 mg per 24 hours. In this group, the benefits of 4-year treatment with fosinopril were sustained during posttrial follow-up for cardiovascular mortality and morbidity. We propose that UAE be used to estimate risk in the general population and that large clinical trials be designed to confirm the hypothesis that angiotensin-converting enzyme-inhibitor treatment may be beneficial in patients with mildly elevated UAE despite the absence of other comorbidities. Copyright (c) 2011 Mosby, Inc. All rights reserved.
Clinical Trials Related to Optison (Albumin Human)
Evaluate Effect of Optison on Pulmonary Artery Systolic Pressure and Pulmonary Vascular Resistance [Recruiting]
Determination of a Safe Dose of Optison in Pediatric Patients With Solid Tumors [Suspended]
St. Jude Children's Research Hospital is studying ways to make ultrasound images clearer - to
be able to see blood vessels, body structures, and tumors better. Ultrasound uses sound waves
to create pictures, allowing doctors and other medical professionals to "see" inside the
Researchers are studying a contrast agent (like a dye) called Optison™. St. Jude Children's
Research Hospital researchers want to learn the best and safest dose of this ultrasound
Dose-Finding, Feasibility Study of Optison in Contrast Enhanced U/S for the Detection of Carotid Artery Disease [Recruiting]
The purpose of this study is to find the optimal dose from 3 different dose levels - 0. 15
mL, 0. 5 mL and 1. 5 mL of Optison in assessing the presence of disease of the carotid
arteries when comparing pre-contrast to post-contrast ultrasound (U/S) by dose group.
A Prospective Surveillance Trial to Evaluate the Safety of Optison in Clinical Practice. [Recruiting]
This prospective surveillance trial will gather safety information for Optison when it is
used in routine practice.
CeVUS With Intravesical Administration of OPTISON TM (Trademark) in Children [Recruiting]
In this clinical trial the investigators aim to evaluate the diagnostic feasibility and
safety of ceVUS with the intravesical use of OPTISON for vesicoureteral reflux detection and
urethral imaging in children.