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Optison (Albumin Human) - Summary

 


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WARNING: Serious Cardiopulmonary Reactions

Serious cardiopulmonary reactions, including fatalities, have occurred during or within 30 minutes following perflutren-containing microsphere administration.

  • Assess all patients for the presence of any condition that precludes OPTISON administration (see CONTRAINDICATIONS).
  • Monitor patients during and for 30 minutes following OPTISON administration, including vital sign measurements and electrocardiography in all patients and cutaneous oxygen saturation in patients at risk for hypoxemia. Always have resuscitation equipment and trained personnel readily available (see WARNINGS).
 

OPTISON SUMMARY

OPTISON™ (Perflutren Protein-Type A Microspheres for Injection, USP) is a sterile non-pyrogenic suspension of microspheres of human serum albumin with perflutren for contrast enhancement during the indicated ultrasound imaging procedures. The vial contains a clear liquid lower layer and a white upper layer that, after resuspension by gentle mixing, provides a homogeneous, opaque, milky-white suspension for intravenous injection.

OPTISON is indicated for use in patients with suboptimal echocardiograms to opacify the left ventricle and to improve the delineation of the left ventricular endocardial borders.


See all Optison indications & dosage >>

OPTISON NEWS HIGHLIGHTS

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Published Studies Related to Optison (Albumin Human)

Paricalcitol reduces albuminuria and inflammation in chronic kidney disease: a randomized double-blind pilot trial. [2008.08]

Recombinant human growth hormone increases albumin and prolongs survival in patients with chronic liver failure: a pilot open, randomized, and controlled clinical trial. [2008.07]

Effect of maternal egg consumption on breast milk ovalbumin concentration. [2008.07]

HES 130/0.4 (Voluven) or human albumin in children younger than 2 yr undergoing non-cardiac surgery. A prospective, randomized, open label, multicentre trial. [2008.06]

Midodrine versus albumin in the prevention of paracentesis-induced circulatory dysfunction in cirrhotics: a randomized pilot study. [2008.06]

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Clinical Trials Related to Optison (Albumin Human)

Determination of a Safe Dose of Optison in Pediatric Patients With Solid Tumors [Suspended]

A Prospective Surveillance Trial to Evaluate the Safety of Optison in Clinical Practice. [Recruiting]

Microbubble-Enhanced Clotbust Treatment of Acute Ischemic Stroke [Terminated]

Prospective Analysis and Comparison of Stress Echo to Real-Time Myocardial Contrast Stress Echo [Available]

Pre-Operative Evaluation of Kidney & Pancreas Transplant Patients [Recruiting]

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Page last updated: 2008-11-29

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