NEWS HIGHLIGHTSMedia Articles Related to Ophthetic (Proparacaine Ophthalmic)
Abdominal Surgery Without General Anesthesia Source: GastroIntestinal / Gastroenterology News From Medical News Today [2009.11.04] A recent review in Faculty of 1000 Medicine Reports, a publication in which clinicians highlight advances in medical practice, suggests regional pain relief could be used during abdominal surgery. In this review, Michael Schaefer recommends a new approach that can be performed without the need for general anaesthetics.
Anesthesia, Exertional Heat Deaths May Be Linked Source: MedicineNet Hyperthermia Specialty [2009.10.26] Title: Anesthesia, Exertional Heat Deaths May Be Linked Category: Health News Created: 10/23/2009 4:10:00 PM Last Editorial Review: 10/26/2009
Anesthesia in Youngest Kids May be Linked to Learning Disabilities Source: MedicineNet Hernia Specialty [2009.03.25] Title: Anesthesia in Youngest Kids May be Linked to Learning Disabilities Category: Health News Created: 3/25/2009 2:00:00 AM Last Editorial Review: 3/25/2009
Need For Emergency Airway Surgery For Hard-to-Intubate Patients Reduced Source: Respiratory / Asthma News From Medical News Today [2009.11.18] Be prepared, that old Boy Scout motto, is being applied with great success to operating room patients whose anatomy may make it difficult for physicians to help them breathe during surgery, Johns Hopkins researchers report in a new study. When patients undergo general anesthesia, they stop breathing on their own and anesthesiologists must quickly insert a tube into the airway as a first step in machine-assisted breathing.
New Technique For Injectable Facial Fillers Improves Comfort, Recovery Source: Cosmetic Medicine / Plastic Surgery News From Medical News Today [2009.10.29] Less pain during injections for wrinkle-fighting facial fillers. Less swelling afterward. Less time in the office waiting for anesthesia to take effect. These and other benefits of a new injection technique that UT Southwestern Medical Center plastic surgeons are helping pioneer are outlined in the October issue of Plastic and Reconstructive Surgery.
Published Studies Related to Ophthetic (Proparacaine Ophthalmic)
Subtenon lidocaine vs topical proparacaine in adult strabismus surgery. [2006.09] Intraoperative subtenon 2% lidocaine and topical 0.5% proparacaine in patients undergoing strabismus surgery were compared. No additional systemic analgesics and sedatives were used.Topical 0.5% proparacaine may be preferred because of its easy administration and fewer side effects, lack of hospital admission, and immediate and predictable alignment of the eyes.
Duration of effect and effect of multiple doses of topical ophthalmic 0.5% proparacaine hydrochloride in clinically normal dogs. [2005.01] OBJECTIVE: To determine the duration of effect and the effect of multiple doses of topical ophthalmic application of 0.5% proparacaine hydrochloride on corneal sensitivity in clinically normal dogs...
Topical proparacaine and episcleral venous pressure in the rabbit. [2009.06] PURPOSE: To determine the effect of proparacaine-induced topical anesthesia on episcleral venous pressure (EVP)... CONCLUSIONS: These results suggest that the episcleral circulation is under tonic neural control and that either an upstream resistance site is under tonic vasodilatory control or a downstream site is under vasoconstrictor control.
Evaluation of duration of corneal anesthesia induced with ophthalmic 0.5% proparacaine hydrochloride by use of a Cochet-Bonnet aesthesiometer in clinically normal horses. [2008.12] Objective-To measure duration of corneal anesthesia and time and degree of maximal anesthetic effect of 0.5% proparacaine hydrochloride by use of a Cochet-Bonnet aesthesiometer in horses... Conclusions and Clinical Relevance-Duration of corneal anesthesia in horses was shorter than in dogs, and degree of maximal effect was less than in cats and dogs, most likely because of increased sensitivity of the equine cornea, compared with corneal sensitivity in those species.
Effect of proparacaine on central corneal thickness values: an evaluation using noncontact specular microscopy and pentacam. [2007.01] PURPOSE: To study the effect of 1 drop of 0.5% proparacaine on central corneal thickness values monitored by nonspecular microscopy and Pentacam, a corneal topographer with rotating Scheimpflug camera... CONCLUSION: One drop of 0.5% proparacaine does not produce any significant change in central corneal thickness.
Clinical Trials Related to Ophthetic (Proparacaine Ophthalmic)
Clinical Assessment of an in-Patient Glucose Monitoring System (Accu-Chek Inform Cobas IT 1000) [Completed]
The principal objective of this single-center 2-period study is to evaluate the glycemic
control of in-patients in 3 hospital departments (Diabetology, Cardiology and Pulmonary Care)
as the rate of capillary blood glucose measurements within a pre-define target range, and to
compare results during the period I (warning of the Accu-Check Inform glucose meter on
glucose levels not activated) and period II (warning activated).
Proparacaine vs Placebo for Corneal Injuries [Completed]
Introduction: Traumatic injuries to the outer covering of the eye (the cornea) are a common
emergency department complaint. They cause significant patient distress including pain, loss
of sleep and missed work days. There is currently no accepted, uniform approach to pain
management in this patient population. Emergency medicine and ophthalmology texts state that
prolonged use of medications that anesthetize the cornea is not recommended. Several recent
publications in the ophthalmology literature show that the outpatient use of dilute local
anesthesia in patients after eye surgery is a safe and effective method of pain control. In
this study, we used Proparacaine (a local anesthetic), in a similar manner, for the
outpatient emergency department management of traumatic corneal injuries.
Methods: We performed a clinical trial on a sample of adult patients presenting with
traumatic corneal injuries to two university affiliated emergency departments in London,
Canada.
Patients providing signed informed consent to participate in the study received a vial of
clear liquid that contained either Proparacaine or plain water (placebo), a pain log, topical
antibiotics and oral Acetaminophen (Tylenol) with Codeine for breakthrough pain.
Patients were instructed to use the "study drug" on an "as-needed" basis for the next seven
days. Patients completed a pain scale describing their discomfort immediately prior to, and
five minutes after self-administration of the study drug. All patients were followed closely
in an ophthalmology outpatient clinic on Days 1, 3 and 5 after presentation to the emergency
department. At the last ophthalmology clinic visit, the patients' pain logs were collected.
The protocol was approved by the Research Ethics Board for Health Sciences Research
Involving Human Subjects at the University of Western Ontario.
Remote Management of Diabetic Patients Via Data Transmission by Accu-Chek 360 Software [Not yet recruiting]
Impact of Accu-Chek 360 in Veterans With Type 2 Diabetes [Not yet recruiting]
To show that a structured treatment plan based upon Accu-Chek 360 View has a favorable
effect on physician decision-making and HbA1c for patients on oral hypoglycemic agents (OHA)
or insulin for type 2 diabetes (T2D).
Hypothesis 1: Compared to controls, intervention subjects will undergo a greater number of
medication changes and have a lower HbA1 at the conclusion of the study.
Hypothesis 2: Higher rates of monitoring at entry will be associated with lower CHO
consumption, lower percent body fat, higher medication compliance, and higher physical
activity levels.
Hypothesis 3: Patients with lower rates of monitoring at entry will have higher rates of
depression, more likely to have an external locus of control, and express greater fear about
self-testing.
Comparison of Tetracaine 0.5% and Lidocaine 2% Jelly for Topical Phacoemulsification Cataract Surgery [Recruiting]
The purpose of this study is to determine if there is a difference on the penetration of
betadine 5% when using lidocaine 2% jelly versus topical tetracaine 0. 5% in topical cataract
surgery. This will be assessed comparing bacterial colony count and species by taking swabs
from the eye surface before and after the topical anesthesia has been administered.
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