NEWS HIGHLIGHTS
Published Studies Related to Omnitrope (Somatropin Subcutaneous)
Effect of the inhaled corticosteroid mometasone on small airway patency in patients with asthma. [2009.05]
The inflammation in asthma involves both the large and the small airways. This study was designed to examine whether mometasone delivered from a dry powder inhaler would improve those parameters thought to reflect patency and obstruction of the small airways (diameter <2 mm)... Mometasone delivered by a dry powder inhaler improved asthma control and pulmonary function in tests reflecting both large and small airways.
Clinical Trials Related to Omnitrope (Somatropin Subcutaneous)
Extension Study on Safety of Long-Term Growth Hormone Replacement in Adult Patients With Growth Hormone Deficiency [Completed]
To evaluate long-term safety of growth hormone replacement in adult patients with growth
hormone deficiency
Cool.Click™ Adolescent Transition Study: Study of Saizen® in Subjects With Childhood-Onset Growth Hormone Deficiency [Completed]
The primary objective is to evaluate the efficacy and safety of two different dose regimens
of r-hGH (Saizen®) in subjects with childhood-onset growth hormone deficiency (COGHD) during
the transition phase from childhood to adulthood.
Effect of Growth Hormone in Children With Growth Hormone Deficiency [Completed]
This trial was conducted in the United States of America (USA).
The purpose of the trial was to compare the effect of Norditropin® using different dosing
regimens in children suspected of growth hormone deficiency.
Growth Hormone Administration and Its Effects on Cardiovascular Risk Factors in Growth Hormone Deficient Women [Completed]
The purpose of the study is to evaluate the effects of growth hormone replacement on women
with growth hormone deficiency. Growth hormone deficiency means the body no longer produces
growth hormone due to a tumor or some kind of disease of the brain in an area called the
pituitary/hypothalamic region. This is the area of the brain where growth hormone is
normally produced. We, the researchers at Massachusetts General Hospital, will establish the
effects of growth hormone replacement on cardiovascular parameters (laboratory tests, the
flexibility of the arteries, changes in heart rate) in women with growth hormone deficiency.
Our goal is to see if this therapy:
- has effects on women's cardiovascular risk markers (special blood tests which indicate
how healthy the heart and arteries are)
- has effects on women's types and levels of various substances circulating in their
blood
- in women affects the stiffness of their arteries and heart rate variability in parallel
with changes in cardiovascular risk markers
- has different effects depending on whether women are pre or post menopausal.
Participation in this study is expected to last approximately 12 months.
Growth Hormone to Increase Immune Function in People With HIV [Active, not recruiting]
Growth hormone plays an important role in the development of the immune system. Studies
suggest that growth hormone may promote growth of the thymus, a gland responsible for the
production of important immune cells called T cells. Since these cells are lost during the
course of HIV infection, it is possible that growth hormone treatment could help restore the
immune system. This study will determine whether the administration of growth hormone can
increase the size and function of the thymus and cause an increase in the number of new T
cells in the blood of people infected with HIV.
Study hypothesis: Growth hormone treatment will enhance T cell production in HIV infected
adults.
|
