Media Articles Related to Olux (Clobetasol Topical)
Stem Cells Show Promise as Treatment for Moderate to Severe Atopic Dermatitis
Source: Medscape Pathology & Lab Medicine Headlines [2016.06.21]
Subcutaneous injection of human umbilical cord blood-derived stem cells appears to improve the features of atopic dermatitis, according to results from an early trial.
Reuters Health Information
Atopic dermatitis: Positive topline Phase 3 results announced for dupilumab
Source: Clinical Trials / Drug Trials News From Medical News Today [2016.06.06]
Regeneron Pharmaceuticals, Inc. and Sanofi have announced that a one-year Phase 3 study, known as LIBERTY AD CHRONOS, evaluating investigational dupilumab met its primary and key secondary...
Eczema (Atopic Dermatitis) Causes, Symptoms, Treatment
Source: MedicineNet Atopic Dermatitis Specialty [2016.05.24]
Title: Eczema (Atopic Dermatitis) Causes, Symptoms, Treatment
Created: 3/26/2012 12:00:00 AM
Last Editorial Review: 5/24/2016 12:00:00 AM
Source: MedicineNet Seborrhea Specialty [2016.03.18]
Title: Seborrheic Dermatitis
Category: Diseases and Conditions
Created: 3/16/2012 12:00:00 AM
Last Editorial Review: 3/18/2016 12:00:00 AM
Source: MedicineNet Otitis Externa Specialty [2015.10.09]
Title: Atopic Dermatitis
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 10/9/2015 12:00:00 AM
Published Studies Related to Olux (Clobetasol Topical)
Clobetasol propionate, 0.05%, vs hydrocortisone, 1%, for alopecia areata in
children: a randomized clinical trial. 
IMPORTANCE: Alopecia areata is an idiopathic cause of hair loss with limited
therapeutic repertoire. OBJECTIVE: To compare the efficacy and safety of a high- vs low-potency topical
corticosteroid in pediatric patients...
A comparative study in efficacy and safety of 0.1% tacrolimus and 0.05%
clobetasol propionate ointment in discoid lupus erythematosus by modified
cutaneous lupus erythematosus disease area and severity index. 
CONCLUSION: The present study proved the efficacy of twice-daily tacrolimus and
A double-blind, randomized, placebo-controlled trial of topical tacrolimus 0.1% vs. clobetasol propionate 0.05% in childhood vitiligo. [2011.09]
BACKGROUND: Both clobetasol propionate 0.05% (CP 0.05%) and tacrolimus 0.1% (T 0.1%) ointments have been shown to be efficacious and safe in treating vitiligo in the paediatric population. OBJECTIVES: To assess efficacy and safety of these two therapies compared with each other and with placebo... CONCLUSIONS: Both CP 0.05% and T 0.1% ointments offer similar benefit in paediatric vitiligo, both facial and nonfacial. The facial lesions responded faster than the nonfacial ones. (c) 2011 The Authors. BJD (c) 2011 British Association of Dermatologists.
Clobetasol propionate 0.05% spray for the management of moderate-to-severe plaque psoriasis of the scalp: results from a randomized controlled trial. [2011.08]
BACKGROUND: Clobetasol propionate 0.05% spray is available for treating moderate-to-severe plaque psoriasis; however, there is limited information with plaque psoriasis of the scalp. OBJECTIVE: Evaluate the efficacy, safety, and quality-of-life impact of clobetasol propionate 0.05% spray in patients with moderate to severe plaque psoriasis of the scalp... CONCLUSION: Treatment with clobetasol propionate 0.05% spray for up to four weeks is effective and well tolerated for moderate-to-severe plaque psoriasis of the scalp.
Comparison of clobetasol propionate cream plus coal tar vs. topical psoralen and solar ultraviolet A therapy in palmoplantar psoriasis. [2011.08]
AIM: Palmoplantar psoriasis (PPP) produces significant morbidity and requires prompt treatment. Topical agents form the mainstay of therapy. We compared the efficacy and side-effect profile of a steroid/coal-tar combination with topical psoralen and solar ultraviolet A (PUVAsol) in PPP... CONCLUSION: Both treatments had comparable efficacy. In both groups, patients experienced 'good improvement' after 16 weeks of therapy. (c) The Author(s). CED (c) 2011 British Association of Dermatologists.
Clinical Trials Related to Olux (Clobetasol Topical)
A Comparison Between Clobetasol Propionate 0.05% (Clobex�) Spray and Clobetasol Propionate 0.05% (Olux�) Foam [Completed]
Comparison of Efficacy of Intralesional Triamcinolone Injection and Clobetasol Propionate Ointment for Psoriatic Nails [Completed]
Psoriatic nails can significantly affect a quality of life of patients. Psoriasis affects
both nail matrix and nail bed. Pitting, leukonychia and red spots in lunula indicate a
defect in the nail matrix. Psoriasis can change the nail bed as the results in onycholysis,
discoloration, splinter hemorrhage and subungual hyperkeratosis. The main treatment of
psoriatic nails is using topical high- potent steroids however topical steroids are limited
their ability to penetrate deep nail matrix or nail bed which are the main pathology. Use of
such a treatment can lead to skin atrophy and report in the case of "Disappearing digits".
Previous studies of steroid injection in the treatment of psoriatic nails show satisfactory
results without any serious permanent adverse effects. At present, there is no comparison
study between intralesional steroid and ultrapotent topical steroid for the treatment of
The purpose of the study is to evaluate the efficacy and safety of intralesional
triamcinolone comparing to 0. 05% clobetasol ointment in the treatment of psoriatic nails.
A Study to Evaluate the Efficacy and Tolerability of Topical Therapies for the Condition of Plaque-Type Psoriasis [Completed]
The purpose of the study is to determine the efficacy and safety of two different forms of a
topical steroid (clobetasol propionate) in patients with plaque-type psoriasis.
Efficacy/Safety/Subject Satisfaction/Duration of Response of Clobetasol Propionate Spray vs Ointment in Plaque Psoriasis [Completed]
This study is a comparison between Clobetasol Propionate Spray and Clobetasol Propionate
Ointment with Regard to Efficacy, Safety, Subject Satisfaction and Duration of Response in
Moderate to Severe Stable Plaque Psoriasis. Subjects will be enrolled and randomized into
one of two groups: clobetasol propionate Spray for 4 weeks of treatment or clobetasol
propionate ointment for 2 weeks of treatment with a 2 week follow-up visit for each group.
Clobetasol for Oral Graft-Versus-Host Disease [Recruiting]
- Oral graft-versus-host disease (GVHD) is a possible complication of bone marrow
transplants. It is the result of the donor cells trying to attack the recipient s body.
Symptoms include dry mouth, sensitivity and pain when tasting certain spices and flavors,
and painful swallowing. Steroids are a possible effective treatment for GHVD, but they can
cause side effects when given as pills or injections. Steroids given in a cream or rinse
form, applied directly to the site of the symptoms, can have fewer side effects. However,
their effectiveness as a rinse has not been tested in the mouth. Researchers want to see if
a steroid called clobetasol can be used as a mouth rinse to treat oral GHVD.
- To see if a clobetasol rinse is a safe and effective treatment for oral graft-versus-host
- Individuals at least 12 years of age who have oral GHVD and are not allergic to
- Participants will be screened with a physical exam and medical history. Blood and urine
samples will be collected. They will also have an oral exam, a mouth tissue biopsy, and
other tests before starting the study drug.
- Participants will be separated into two groups. One group will receive clobetasol; the
other will have a placebo liquid.
- Participants will rinse their mouths with the study liquid three times a day after
meals for 2 weeks.
- After 2 weeks, participants will have another study visit with blood tests and other
- After the study visit, all participants will start to use the clobetasol rinse. Those
who originally had clobetasol will use the rinse for another 2 weeks. Those who
originally had a placebo will use the rinse for 4 weeks.
- Participants will have a follow-up exam after the end of treatment.