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Nitroglycerin (Nitroglycerin) - Summary

 


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NITROGLYCERIN SUMMARY

NITROGLYCERIN TRANSDERMAL SYSTEM
0.1, 0.2, 0.4 and 0.6 mg/hr

FOR INTRAVENOUS USE ONLY. NOT FOR DIRECT INTRAVENOUS INJECTION. NITROGLYCERIN INJECTION, USP MUST BE DILUTED IN 5% DEXTROSE INJECTION, USP, OR 0.9% SODIUM CHLORIDE INJECTION, USP PRIOR TO ITS INFUSION (SEE DOSAGE AND ADMINISTRATION SECTION). THE ADMINISTRATION SET USED FOR INFUSION WILL AFFECT THE AMOUNT OF NITROGLYCERIN DELIVERED TO THE PATIENT (SEE WARNINGS, AND DOSAGE AND ADMINISTRATION SECTIONS).

CAUTION: SEVERAL PREPARATIONS OF NITROGLYCERIN FOR INJECTION ARE AVAILABLE. THEY DIFFER IN CONCENTRATION AND/OR VOLUME PER VIAL. WHEN SWITCHING FROM ONE PRODUCT TO ANOTHER ATTENTION MUST BE PAID TO THE DILUTION AND DOSAGE AND ADMINISTRATION INSTRUCTIONS.

Nitroglycerin is 1,2,3-propanetriol trinitrate, an organic nitrate.

Nitroglycerin Injection, USP is indicated for treatment of perioperative hypertension; for control of congestive heart failure in the setting of acute myocardial infarction; for treatment of angina pectoris in patients who have not responded to sublingual nitroglycerin and β-blockers; and for induction of intraoperative hypotension.


See all Nitroglycerin indications & dosage >>

NITROGLYCERIN NEWS HIGHLIGHTS

Published Studies Related to Nitroglycerin

The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients. [2008.10]

Intravenous nitroglycerin for prevention of pancreatitis after therapeutic endoscopic retrograde cholangiography: a randomized, double-blind, placebo-controlled multicenter trial. [2008.08]

Efficacy of nitroglycerine infusion versus sublingual nifedipine in severe pre-eclampsia: a randomized, triple-blind, controlled trial. [2008.05]

The effect of intravenous nitroglycerine on blood pressure during intubation. [2008.02]

Effects of sublingual nitroglycerin on coronary lumen diameter and number of visualized septal branches on 64-MDCT angiography. [2008.01]

more >>

Clinical Trials Related to Nitroglycerin

MQX-503 vs Nitroglycerin Ointment: A Pharmacokinetic Comparison in Normal Subjects [Completed]

A Study of a Topical Form of Nitroglycerin and Placebo in the Treatment and Prevention of Raynaud's Phenomenon [Active, not recruiting]

Blood Pressure Interaction Between Sildenafil and Sublingual Glyceryl Trinitrate (GTN) in Men With Angina [Completed]

Nitrate and Hypertension in Heart Transplanted Patients [Completed]

Radial Artery Dilation Study: The Effect of Topical Administration of Nitroglycerin and Lidocaine Versus Lidocaine Alone of the Radial Artery Diameter [Recruiting]

more >>

Page last updated: 2008-11-03

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