Nitro-Bid (Nitroglycerin Topical) - Side Effects and Adverse Reactions

ADVERSE REACTIONS:

Adverse reactions to nitroglycerin are generally dose-related, and almost all of these reactions are the result of nitroglycerin's activity as a vasodilator. Headache, which may be severe, is the most commonly reported side effect. Headache may be recurrent with each daily dose, especially at higher doses. Transient episodes of lightheadedness, occasionally related to blood pressure changes, may also occur. Hypotension occurs infrequently, but in some patients it may be severe enough to warrant discontinuation of therapy. Syncope, crescendo angina, and rebound hypertension have been reported but are uncommon.

Allergic reactions to nitroglycerin are also uncommon, and the great majority of those reported have been cases of contact dermatitis or fixed drug eruptions in patients receiving nitroglycerin in ointments or patches. There have been a few reports of genuine anaphylactoid reactions, and these reactions can probably occur in patients receiving nitroglycerin by any route.

Extremely rarely, ordinary doses of organic nitrates have caused methemoglobinemia in normal-seeming patients; for further discussion of its diagnosis and treatment see OVERDOSAGE .

Data are not available to allow estimation of the frequency of adverse reactions during treatment with nitroglycerin ointment.

REPORTS OF SUSPECTED NITRO-BID SIDE EFFECTS / ADVERSE REACTIONS

Possible Nitro-BID side effects / adverse reactions in 76 year old male

Reported by a consumer/non-health professional from United States on 2012-08-15

Patient: 76 year old male weighing 68.0 kg (149.7 pounds)

Reactions: OFF Label USE, Contusion, Capillaritis

Suspect drug(s):
Nitro-BID

Other drugs received by patient: Pravastatin; Cyanocobalamin; Nefazodone HCL; Fenofibrate; Aspirin

Possible Nitro-BID side effects / adverse reactions in 61 year old male

Reported by a consumer/non-health professional from United States on 2012-08-15

Patient: 61 year old male weighing 125.2 kg (275.4 pounds)

Reactions: OFF Label USE, Dizziness, Drug Dispensing Error, Blood Pressure Fluctuation, Epistaxis

Suspect drug(s):
Nitro-BID

Other drugs received by patient: Propranolol