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Nexium I.V. (Esomeprazole Magnesium) - Summary

 


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NEXIUM I.V. SUMMARY

NEXIUM® I.V.
(esomeprazole sodium)
FOR INJECTION

The active ingredient in NEXIUM® I.V. (esomeprazole sodium) for Injection is (S)-5-methoxy-2[[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methyl]sulfinyl]-1 H -benzimidazole sodium a compound that inhibits gastric acid secretion. Esomeprazole is the S-isomer of omeprazole, which is a mixture of the S- and R- isomers.

NEXIUM I.V. for Injection is indicated for the short-term treatment (up to 10 days) of GERD patients with a history of erosive esophagitis as an alternative to oral therapy in patients when therapy with NEXIUM Delayed-Release Capsules is not possible or appropriate.

When oral therapy is possible or appropriate, intravenous therapy with NEXIUM I.V. for Injection should be discontinued and the therapy should be continued orally.


See all Nexium I.V. indications & dosage >>

NEXIUM I.V. NEWS HIGHLIGHTS

Published Studies Related to Nexium I.V. (Esomeprazole)

Efficacy of esomeprazole (20 mg once daily) for reducing the risk of gastroduodenal ulcers associated with continuous use of low-dose aspirin. [2008.10]

Double-blind, placebo-controlled trial with esomeprazole for symptoms and signs associated with laryngopharyngeal reflux. [2008.09]

Comparing laparoscopic antireflux surgery with esomeprazole in the management of patients with chronic gastro-oesophageal reflux disease: a 3-year interim analysis of the LOTUS trial. [2008.09]

Preoperative administration of esomeprazole has no influence on frequency of refluxes. [2008.05]

The effect of famotidine, esomeprazole, and ezetimibe on levothyroxine absorption. [2008.05]

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Clinical Trials Related to Nexium I.V. (Esomeprazole)

Prevention of Gastric Ulcers [Completed]

Study Comparing the Effects of Esomeprazole Adminstered Orally and Intravenously on Basal and Pentrigastrin-Stimulated Acid Output in Subjects With Symptoms of Gastroesophageal Reflux Disease (GERD) [Completed]

A Pharmacodynamic Study Comparing Zegerid® and Prilosec OTC® [Active, not recruiting]

Ulcer Prevention II [Completed]

A Comparative Efficacy and Safety Study of Nexium Delayed-Release Capsules (40mg qd and 20mg qd) Versus Ranitidine 150mg Bid for the Healing of NSAID-Associated Gastric Ulcers When Daily NSAID Use is Continued [Completed]

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Page last updated: 2008-11-03

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