News related to Neurontin (Gabapentin) and/or conditions it is approved for
Gabapentin Studies for Off-Label Uses Cooked? (CME/CE, with audio)
Source: MedPage Today Neurology [2009.11.11]
Primary outcome measures were apparently a moving target in many company-sponsored studies of gabapentin (Neurontin) for off-label uses such as neuropathic pain and bipolar disorder, researchers have suggested.
Promising Results In Reducing Neuropathic Pain With Combined Drug Treatment, Than With Either Drug Alone
Source: Body Aches News From Medical News Today [2009.09.30]
An article published Online First and in a future edition of The Lancet reports that combination treatment using gabapentin and nortriptyline reduces neuropathic pain more than either drug alone. This treatment could be used in patients that only partly respond to one drug or the other. The article is the work of Professor Ian Gilron, Director of Clinical Pain Research, Queen's University, and Kingston General Hospital, Kingston, Ontario, Canada, and colleagues.
NeuroTherapeutics Pharma Receives Investment From The Epilepsy Therapy Project
Source: Epilepsy News From Medical News Today [2009.11.11]
NeuroTherapeutics Pharma, Inc., or NTP, a biopharmaceutical company focused on developing novel therapies for central nervous system (CNS) disorders, today announced that it received a $100,000 investment from the Epilepsy Therapy Project. The Epilepsy Therapy Project invests in promising research efforts in order to help make new therapies a reality for patients, and the investment in NTP is one of the largest made in its history.
Ikano Therapeutics Receives Orphan Drug Designation For Epilepsy Drug
Source: Epilepsy News From Medical News Today [2009.11.11]
Ikano Therapeutics, Inc. (ITI) announced that it has received Orphan Drug designation for midazolam in the acute treatment of certain forms of epileptic seizure known as cluster seizures or alternatively, as acute repetitive seizures. ITI has a nasally administered form of midazolam called ITI-111 in late stage clinical development that is aimed at the treatment of these specific seizure types in an outpatient setting where other routes of administration can be difficult or inappropriate.
Alzheimer's Society Comment On The Use Of Epilepsy Drugs To Treat Alzheimer's
Source: Epilepsy News From Medical News Today [2009.10.29]
Epilepsy drugs could be developed as a treatment for neurodegenerative diseases according to research published in the journal Molecular Neurodegeneration. The study found that nerve cells lived longer when treated with T-type calcium-channel blockers, which are commonly used to treat epilepsy. 'This study is interesting since other research has shown that anti-convulsant drugs reduce the tangles of proteins linked to Alzheimer's disease.
Alzheimer's And Parkinson's Could Be Treated By Epilepsy Drugs
Source: Epilepsy News From Medical News Today [2009.10.29]
Researchers in the USA have discovered a potential new function for anti-epileptic drugs in treating neurodegenerative disorders such as Alzheimer's and Parkinson's disease. The study, published in BioMed Central's open access journal Molecular Neurodegeneration, found that neurons in the brain were protected after treatment with T-type calcium-channel blockers, which are commonly used to treat epilepsy.
Epilepsy Treatment Is A Possible Culprit For Development Of Schizophrenia
Source: Epilepsy News From Medical News Today [2009.10.21]
Researchers say antiepilectic drug treatments administered when the brain is developing appear to trigger schizophrenia-like behavior in animal models. In humans, having a history of seizures in infancy is a significant risk factor for development of schizophrenia later in life, but it is not known whether the elevated risk is due to seizures themselves, or from side effects antiepileptic drug (AED) treatment.
'Molecular Trigger' For Sudden Death In Epilepsy Revealed By BCM Scientists
Source: Epilepsy News From Medical News Today [2009.10.15]
The most common gene for a syndrome associated with abnormal heart rhythms and sudden death triggers epileptic seizures and could explain sudden unexplained death in epilepsy, said researchers from Baylor College of Medicine in a report that appears today in the journal Science Translational Medicine.
How A Well-Known Epilepsy And Pain Drug Works
Source: Epilepsy News From Medical News Today [2009.10.15]
A Duke University Medical Center researcher who spent years looking for the signals that prompt the brain to form new connections between neurons has found one that may explain precisely how a well-known drug for epilepsy and pain actually works. The finding may also point to new therapies for brain injury and neuropathic pain. The role of neurons in the brain and nervous system is well known, but astrocytes, a different type of brain cell, still are largely a mystery.
Routine Stroke Prevention Therapies Are Underused In The Very Elderly But Could Be Very Effective; And More Research In Epilepsy In Very Old Needed
Source: Epilepsy News From Medical News Today [2009.10.07]
Routine stroke prevention therapies are underused in the very elderly, but could be very effective in this age group. The issues are discussed in a Review published Online First and in the November edition of The Lancet Neurology, written by Dr Nerses Sanossian and Dr Bruce Ovbiagele, University of Southern California, Los Angeles, CA, USA. As the average human lifespan increases there are more individuals above the age of 80 years who have a high quality of life.
Very Elderly Age Group: Need For Routine Stroke Prevention Therapies And Research In Epilepsy
Source: Epilepsy News From Medical News Today [2009.10.05]
A review published Online First and in the November edition of The Lancet Neurology reports that routine stroke prevention therapies are underused in the very elderly, but could be very effective in this age group. The article is the work of Dr Nerses Sanossian of the University of Southern California and Dr Bruce Ovbiagele of the UCLA Stroke Center and Department of Neurology, Los Angeles, CA, USA.
Febrile Seizures And Severe Epilepsy In Infants Traced To A Sodium Channel Gene Mutation
Source: Epilepsy News From Medical News Today [2009.09.20]
Mutations in the SCN9A sodium channel gene are a cause of febrile seizures and contribute to a severe form of epilepsy in infants 6 months and younger, report researchers from the University of Utah, University of Antwerp, and University of Washington.
Discovery Of New Links Between Epilepsy And Brain Lipids
Source: Epilepsy News From Medical News Today [2009.09.19]
In mice that are missing a protein found only in the brain, neural signals "go crazy," leaving the animals with epileptic seizures from a young age, researchers have found. The report in the September 18th Cell, a Cell Press publication, details what it is that happens when the protein encoded by plasticity related gene-1 (PRG-1) gets lost, revealing an important fine-tuning mechanism for brain function.
Study Links Epilepsy to Brain Protein
Source: MedicineNet Seizure Specialty [2009.09.18]
Title: Study Links Epilepsy to Brain Protein
Category: Health News
Created: 9/17/2009 2:10:00 PM
Last Editorial Review: 9/18/2009
Registry To Track Children With Severe Type Of Epilepsy
Source: Epilepsy News From Medical News Today [2009.09.17]
Researchers have launched an online registry that ultimately aims to help children with a severe type of epilepsy that strikes in the first months of life. It is believed to be the first worldwide registry of children with infantile spasms and is a collaboration between Washington University School of Medicine in St. Louis and the University of Chicago.
Drug Shows Promise Against Childhood Epilepsy
Source: MedicineNet Pediatric Epilepsy Surgery Specialty [2009.06.16]
Title: Drug Shows Promise Against Childhood Epilepsy
Category: Health News
Created: 6/16/2009 7:00:00 AM
Last Editorial Review: 6/16/2009
Panel: Avoid Epilepsy Drug in Pregnancy
Source: MedicineNet Spina Bifida and Anencephaly Specialty [2009.04.28]
Title: Panel: Avoid Epilepsy Drug in Pregnancy
Category: Health News
Created: 4/28/2009
Last Editorial Review: 4/28/2009
Epilepsy Drug Linked to Babies' Lower IQ
Source: MedicineNet Bipolar Disorder Specialty [2009.04.16]
Title: Epilepsy Drug Linked to Babies' Lower IQ
Category: Health News
Created: 4/16/2009
Last Editorial Review: 4/16/2009
Epilepsy Drugs Get Suicide Risk Warning
Source: MedicineNet clonazepam Specialty [2008.12.17]
Title: Epilepsy Drugs Get Suicide Risk Warning
Category: Health News
Created: 12/17/2008
Last Editorial Review: 12/17/2008
Epilepsy Drug, Pregnancy Raise Autism Risk
Source: MedicineNet lamotrigine Specialty [2008.12.02]
Title: Epilepsy Drug, Pregnancy Raise Autism Risk
Category: Health News
Created: 12/2/2008
Last Editorial Review: 12/2/2008
FDA Panel: No Warning on Epilepsy Drugs
Source: MedicineNet lamotrigine Specialty [2008.07.11]
Title: FDA Panel: No Warning on Epilepsy Drugs
Category: Health News
Created: 7/11/2008
Last Editorial Review: 7/11/2008
Seizure (Epilepsy)
Source: MedicineNet Gaucher Disease Specialty [2008.05.09]
Title: Seizure (Epilepsy)
Category: Diseases and Conditions
Created: 12/31/1997
Last Editorial Review: 5/9/2008
Calm in the Storm: A Child's Life with Epilepsy
Source: MedicineNet Pediatric Epilepsy Surgery Specialty [2006.12.01]
Title: Calm in the Storm: A Child's Life with Epilepsy
Category: Health Tips
Created: 12/1/2006
Last Editorial Review: 12/1/2006
Increased Risk Of Seizures Faced By Current Cigarette Smokers
Source: Health News from Medical News Today [2009.11.19]
A recent study determined there is a significant risk of seizure for individuals who currently smoke cigarettes. Boston-based researchers from Brigham and Women's Hospital and Harvard Medical School also found that long-term, moderate intake of caffeine or alcohol does not increase the chance of having a seizure or developing epilepsy.
Registry To Track Children With Infantile Spasms
Source: Epilepsy News From Medical News Today [2009.10.10]
Researchers have launched an online registry that ultimately aims to help children with a severe type of epilepsy that strikes in the first months of life. It is believed to be the first worldwide registry of children with infantile spasms and is a collaboration between Washington University School of Medicine in St. Louis and the University of Chicago.
Researchers Question The Use Of Antiepileptic Drugs During Pregnancy
Source: Epilepsy News From Medical News Today [2009.09.30]
New research to be published in BJOG: An International Journal of Obstetrics and Gynaecology reports the pregnancy complications experienced by women with epilepsy and examines the use of antiepileptic drugs (AED) for treatment during pregnancy. Epileptic women (around 0.3-0.7% of the population) who become pregnant are classified as high-risk because prolonged fits can be dangerous for the baby as well as the mother.
Are Syncope And Implantable Loop Recorders Good Value For Money?
Source: Epilepsy News From Medical News Today [2009.09.03]
The REVISE Study (Reveal in the Investigation of Syncope and Epilepsy) found that 1 in 8 adult patients in the United Kingdom, previously thought to be suffering from epilepsy or in whom this diagnosis was in doubt, in fact had symptoms as a result of an abnormal pattern of heart beating, commonly found in patients with syncope (fainting).
|
