Neurontin® (gabapentin) Capsules, Neurontin® (gabapentin) Tablets, and Neurontin® (gabapentin) Oral Solution are supplied as imprinted hard shell capsules containing 100 mg, 300 mg, and 400 mg of gabapentin, elliptical film-coated tablets containing 600 mg and 800 mg of gabapentin or an oral solution containing 250 mg/5 mL of gabapentin.
Neurontin (gabapentin) is indicated for the management of postherpetic neuralgia in adults.
Neurontin (gabapentin) is indicated as adjunctive therapy in the treatment of partial seizures with and without secondary generalization in patients over 12 years of age with epilepsy. Neurontin is also indicated as adjunctive therapy in the treatment of partial seizures in pediatric patients age 3 12 years.
Media Articles Related to Neurontin (Gabapentin)
Updated epilepsy classification may lead to advances in diagnosis, treatment, and research
Source: Epilepsy News From Medical News Today [2017.03.10]
It has been nearly three decades since experts published a classification system related to epilepsy.
Modified Atkins diet helps children with rare form of epilepsy
Source: Epilepsy News From Medical News Today [2017.02.24]
Doose syndrome or myoclonic-astatic epilepsy is a rare syndrome accounting for one to two percent of childhood epilepsies.
Significant epilepsy gene discovery in dogs
Source: Epilepsy News From Medical News Today [2017.02.22]
Researh groups from the University of Helsinki, the LMU Munich and the University of Guelph have described in collaboration a novel myoclonic epilepsy in dogs and identified its genetic cause.
Epilepsy drug discovered in fish model shows promise in small pediatric clinical trial
Source: Clinical Trials / Drug Trials News From Medical News Today [2017.02.13]
"Bench-to-bedside" describes research that has progressed from basic science in animal models that has led to therapies used in patients.
Many older adults with epilepsy may not be receiving optimal care
Source: Epilepsy News From Medical News Today [2017.02.10]
Many older adults with newly diagnosed epilepsy in the United States are being prescribed older anti-epileptic drugs (AEDs), and only half begin treatment with AEDs within the first 30 days of a...
Published Studies Related to Neurontin (Gabapentin)
Comparing Gabapentin with Clonazepam for Residual Sleeping Problems following
Antidepressant Therapy in Patients with Major Depressive Disorder: A Randomized
Clinical Trial. 
for treating residual sleeping disturbances... CONCLUSION: This study revealed that gabapentin is comparable to clonazepam for
The effect of a combination of gabapentin and donepezil in an experimental pain
model in healthy volunteers: Results of a randomized controlled trial. 
This double-blind, placebo-controlled, 3-period cross-over, 4-treatment option,
incomplete block study (ClinicalTrials.gov number NCT01485185), with an adaptive
design for sample size re-estimation, was designed to evaluate gabapentin plus
donepezil in an established experimental model of electrical hyperalgesia...
Efficacy and safety of gabapentin for treatment of postherpetic neuralgia: a
meta-analysis of randomized controlled trials. 
gabapentin for management of PHN... CONCLUSION: This meta-analysis indicates that gabapentin is an effective and
Sleep parameters and health-related quality of life with bazedoxifene/conjugated
estrogens: a randomized trial. 
and active-controlled phase 3 trial... CONCLUSIONS: Symptomatic postmenopausal women who are treated with BZA/CE for 1
The effects of gabapentin on methadone based addiction treatment: a randomized
controlled trial. 
Gabapentin is a potentially useful drug in alleviating the hyperexcitatory
painful states in the control of opiate dependence in acute detoxification and
the stabilization phase. This study aim was to evaluate the effectiveness of
gabapentin adds-on methadone therapy on lowering the methadone... This drug leads to
relief of withdrawal symptoms and lower methadone consumption.
Clinical Trials Related to Neurontin (Gabapentin)
Gabapentin for Smoking Cessation [Completed]
Gabapentin is an anti-epileptic agent that has shown preliminary evidence of efficacy for
improving symptoms of cocaine and alcohol withdrawal in pilot studies. Since the
neurobiology of alcohol, cocaine and nicotine withdrawal is similar, the preliminary
evidence of efficacy of gabapentin for symptoms of alcohol and cocaine withdrawal suggests,
that gabapentin might likely help nicotine withdrawal symptoms and thus tobacco abstinence.
The effect of gabapentin on two of the neurotransmitters, gamma-aminobutyric acid (GABA) and
glutamate further suggest a potential therapeutic mechanism for gabapentin in tobacco
abstinence. However, the exact mechanism of action of gabapentin is currently not known.
We have recently completed an open label pilot trial of gabapentin for tobacco abstinence
involving 50 smokers. The findings from that study provide promising preliminary results
and suggest that further testing of gabapentin for helping cigarette smokers quit tobacco
use is worth pursuing. Overall, gabapentin is well tolerated and has low abuse potential.
Our goal is to evaluate novel, safe, acceptable, and effective therapies that may help
increase tobacco abstinence rates. Currently, no randomized trials testing the efficacy of
gabapentin for smoking abstinence have been published. While our previous study provides
promising evidence regarding the potential efficacy of gabapentin for smoking abstinence, an
additional dose ranging study is needed prior to pursuing a large randomized trial. The
primary aim of the dose ranging study will be to obtain additional evidence of efficacy, and
information on the optimal dose of gabapentin to employ in the larger randomized controlled
Study of the Effect of the Drug Gabapentin on Postoperative Pain and Incidence of Postoperative Nausea and Vomiting [Enrolling by invitation]
Pain Control in Pediatric Posterior Spine Fusion Patients: The Effect of Gabapentin [Recruiting]
The purpose of this study is to evaluate the patient experience when using gabapentin with
other pain control medications after posterior spinal fusion surgery for scoliosis in
adolescents. These results will be compared to patients who underwent the same procedure
during the study period and received the same standardized pain control regimen excluding
gabapentin. Effects on pain level, opioid use, satisfaction and narcotic use after discharge
from the hospital will be measured. Opioid side effects including nausea, sedation and
urinary retention (inability to empty one's bladder) will also be recorded. The null
hypotheses are as follows:
1. There is no significant difference in pain control when adding gabapentin to a
multimodal pain management protocol in pediatric post-operative posterior spinal fusion
2. There is no significant difference in the amount of opiate medication required for pain
control in pediatric post-operative posterior spinal fusion patients.
The Effects of Gabapentin Premedication on Neurosurgery [Recruiting]
The study is to observe the effects of gabapentin premedication on postoperative
pain,vomiting and nausea in patients undergoing neurosurgery. 100 neurosurgical patients are
randomized into groups gabapentin(GG) or placebo(GP). Patients are given gabapentin or
placebo orally the night before operation day and 2hours before surgery,respectively. The
investigators hypothesized that lower incidence of postoperative pain,vomiting and nausea
be observed in GG than GP.
The Effectiveness of Gabapentin for Post-operative Pain Following Cesarean Section [Completed]
Gabapentin has been very effective at treating pain after knee and hip operations,
hysterectomies, and many other types of operations. A previous study at the investigators'
hospital found that a single pre-operative dose of 600mg gabapentin produced a significant
reduction in pain after caesarean section. However, 19% complained of sedation. The purpose
of this study is to see whether a reduced dose of gabapentin will produce a similar
improvement in pain scores while avoiding adverse effects such as sedation or dizziness. The
objective of this study is to compare the efficacy of a single pre-operative oral dose of
gabapentin 300mg, versus 600mg and placebo in women undergoing Cesarean section. The
investigators' hypothesis is that gabapentin 300mg will result in decreased pain scores
similar to gabapentin 600mg, but with reduced side effects.
Reports of Suspected Neurontin (Gabapentin) Side Effects
Drug Ineffective (392),
Feeling Abnormal (116),
Pain in Extremity (115),
Fatigue (96), more >>
PATIENT REVIEWS / RATINGS / COMMENTS
Based on a total of 38 ratings/reviews, Neurontin has an overall score of 6.03. The effectiveness score is 6.84 and the side effect score is 6.63. The scores are on ten point scale: 10 - best, 1 - worst. Below are selected reviews: the highest, the median and the lowest rated.
Neurontin review by 45 year old female patient
|Overall rating:|| || |
|Effectiveness:|| || Highly Effective|
|Side effects:|| || No Side Effects|
|Condition / reason:|| || difficulty sleeping because of nervous system prob|
|Dosage & duration:|| || 500 mg at bedtime taken daily for the period of 6 years|
|Other conditions:|| || thyroid disease, allergies|
|Other drugs taken:|| || thyroid medication|
|Benefits:|| || Helped to promote sleep without side effects, hangover or any of the other problems associated with other sleep medications. The sleep difficulty was caused by a horrible reaction to another medication called Celexa, which appeared to sensitize my nervous system even after the Celexa was stopped. Ever since taking the Celexa my nervous system has been exquisitely sensitive, with symptoms such as pain, heart palpitations, restless legs, and other such things that totally interrupted my ability to fall asleep and stay asleep.|
|Side effects:|| || None|
|Comments:|| || Used 400-500 mg at bedtime.|
Neurontin review by 53 year old female patient
|Overall rating:|| || |
|Effectiveness:|| || Moderately Effective|
|Side effects:|| || Moderate Side Effects|
|Condition / reason:|| || Chronic pain (neck and migraines)|
|Dosage & duration:|| || 300 mg. taken 3 times per day for the period of 2 years|
|Other conditions:|| || insomnia|
|Other drugs taken:|| || Seroquel, Maxalt, Fosamax|
|Benefits:|| || The course of treatment reduced the severity and the frequency of the neck pain and migraines by about 50%. |
|Side effects:|| || Dizziness and fatigue|
|Comments:|| || the dose was started small and raised gradually to monitor side effects. It was only moderately successful and the side effects were quite a challenge. It was used as a standard prophylactic treatmemt against frequent migraines. |
Neurontin review by 25 year old female patient
|Overall rating:|| || |
|Effectiveness:|| || Ineffective|
|Side effects:|| || Moderate Side Effects|
|Condition / reason:|| || Severe neck pain lasting 8-9 mons|
|Dosage & duration:|| || 1 every 12 hours (dosage frequency: have taken only one so far!) for the period of one|
|Other conditions:|| || Neck pain / severe headaches|
|Other drugs taken:|| || n/a|
|Benefits:|| || Well I just wanted to comment or get some incite on this medication. I was just proscribed this medication yesterday took first one before bed as doctor said and woke up this morning feeling like i had drank a case of beer i stumbled getting up out of bed then i felt like i was dying of thirst was just wondering how normal this was? Oh and i was very sleepy and unable to wake up till nearly noon i started to sober up. I have a 3yr old son that i stay home with so i need to be able to function. when i had spoke to my doctor about the problems i was having i told him that i did not want to be on anything strong i had previously been put on Vicodin, oxy-codone and flexeral i hated it i could not take care of my son i could not function im just trying to find a solution for my pain without being messed up.! See back in October of 2009 i fell backwards into a dresser corner while putting my sons clothes up in welkin closet had two possible fractures and two slipped disks was in a neck brace from oct-feb so please let me know if you have any idea what i can do my insurance will not cover physical therapy unfortunately .....|
|Side effects:|| || dizziness , sleepy , dry mouth very thirsty|
|Comments:|| || treatment was suppose to be to help control neck pain and headaches|
Page last updated: 2017-03-10