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Nesacaine (Chloroprocaine Hydrochloride) - Description

 


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NESACAINE®
(chloroprocaine HCl Injection, USP)
NESACAINE®-MPF
(chloroprocaine HCl Injection, USP)
For Infiltratrion and Nerve Block

DESCRIPTION

Nesacaine and Nesacaine-MPF Injections are sterile non pyrogenic local anesthetics. The active ingredient in Nesacaine and Nesacaine-MPF Injections is chloroprocaine HCl (benzoic acid, 4-amino-2-chloro-2-(diethylamino) ethyl ester, monohydrochloride), which is represented by the following structural formula:

Table 1 Composition of Available Injections

Formula (mg/mL)

Product Identification

Chloroprocaine HCl

Sodium Chloride

Disodium EDTA dihydrate

Methylparaben

Nasacaine 1%

10

6.7

0.111

1

Nesacaine 2%

20

4.7

0.111

1

Nesacaine-MPF 2%

20

4.7

---

---

Nesacaine-MPF 3%

30

3.3

---

---

The solutions are adjusted to pH 2.7−4.0 by means of sodium hydroxide and/or hydrochloric acid. Filled under nitrogen.

Nesacaine and Nesacaine-MPF Injections should not be resterilized by autoclaving.

Page last updated: 2006-05-11

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