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Nembutal (Pentobarbital Sodium) - Summary

 

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NEMBUTAL SUMMARY

NEMBUTAL®
SODIUM SOLUTION
Pentobarbital Sodium Injection, USP

The barbiturates are nonselective central nervous system depressants which are primarily used as sedative hypnotics and also anticonvulsants in subhypnotic doses. The barbiturates and their sodium salts are subject to control under the Federal Controlled Substances Act (See "Drug Abuse and Dependence" section).

Barbiturates are indicated for the following:

Parenteral:

  1. Sedatives.
  2. Hypnotics, for the short-term treatment of insomnia, since they appear to lose their effectiveness for sleep induction and sleep maintenance after 2 weeks (See " Clinical Pharmacology " section).
  3. Preanesthetics.
  4. Anticonvulsant, in anesthetic doses, in the emergency control of certain acute convulsive episodes, e.g., those associated with status epilepticus, cholera, eclampsia, meningitis, tetanus, and toxic reactions to strychnine or local anesthetics.

NEMBUTAL NEWS HIGHLIGHTS

Published Studies Related to Nembutal (Pentobarbital)

Comparison of propofol with pentobarbital/midazolam/fentanyl sedation for magnetic resonance imaging of the brain in children. [2007.09]

Relative abuse liability of GHB in humans: A comparison of psychomotor, subjective, and cognitive effects of supratherapeutic doses of triazolam, pentobarbital, and GHB. [2006.11]

[Comparison of the effectiveness of pentobarbital and thiopental in patients with refractory intracranial hypertension. Preliminary report of 20 patients] [2005.02]

Etomidate versus pentobarbital for sedation of children for head and neck CT imaging. [2004.08]

Pentobarbital vs chloral hydrate for sedation of children undergoing MRI: efficacy and recovery characteristics. [2004.07]

more>>

Clinical Trials Related to Nembutal (Pentobarbital)

Comparison of Effectiveness of Pentobarbital and Thiopental in Patients With Refractory Intracranial Hypertension [Terminated]

Pharmacokinetics and Pharmacodynamics of Pentobarbital in Neonates, Infants, and Children Following Open Heart Surgery [Recruiting]

Prediction of Childhood Epilepsy Outcome in Bangladesh [Completed]

Physiological, Behavioral and Subjective Effects of Drugs (GHB) [Recruiting]

GHB Withdrawal Symptoms and Effectiveness of Treatment With Lorazepam Versus Pentobarbital - 1 [Recruiting]

more>>

Page last updated: 2007-10-18

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