News related to Namenda (Memantine) and/or conditions it is approved for
Enzyme activity bolstered by gene therapy to combat Alzheimer's disease in mice
Source: Genetics News From Medical News Today [2013.12.06]
St. Jude Children's Research Hospital scientists have identified an enzyme that can halt or possibly even reverse the build-up of toxic protein fragments known as plaques in the brains of mice with Alzheimer's disease. The research appeared in a recent edition of the scientific journal Nature Communications.
Source: MedicineNet Advance Medical Directives Specialty [2013.12.05]
Title: Alzheimer's Disease
Category: Diseases and Conditions
Created: 8/26/2008 12:00:00 AM
Last Editorial Review: 12/5/2013 12:00:00 AM
Vascular changes in the neck may play role in Alzheimer's disease
Source: Seniors / Aging News From Medical News Today [2013.11.28]
Studies on Alzheimer's disease and other forms of dementia have long focused on what's happening inside the brain. Now an international research team studying Alzheimer's and mild cognitive impairment is reporting potentially significant findings on a vascular abnormality outside the brain.
Progression of Alzheimer's disease may be slowed by stress reduction through meditation
Source: Complementary Medicine / Alternative Medicine News From Medical News Today [2013.11.20]
It's well known that the brains of meditators change, but it's not entirely clear what those changes mean or how the changes might benefit the meditator.
Novel genomic approach reveals gene mutation isn't simple answer in familial Alzheimer's disease
Source: Stem Cell Research News From Medical News Today [2013.11.18]
Researchers at the University of California, San Diego School of Medicine have used genetic engineering of human induced pluripotent stem cells to specifically and precisely parse the roles of a key mutated protein in causing familial Alzheimer's disease (AD), discovering that simple loss-of-function does not contribute to the inherited form of the neurodegenerative disorder.
New compound inhibits cognitive impairment in animal models of Alzheimer's disease
Source: Clinical Trials / Drug Trials News From Medical News Today [2013.11.13]
The novel compound IRL-1620 may be useful in treating Alzheimer's disease (AD) as it has been shown to prevent cognitive impairment and oxidative stress in animal models. This research is being presented at the 2013 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition, the world's largest pharmaceutical sciences meeting, in San Antonio, Nov. 10 - 14.
FDA approves second brain imaging drug to help evaluate patients for Alzheimer's disease, dementia
Source: MRI / PET / Ultrasound News From Medical News Today [2013.10.30]
The U.S. Food and Drug Administration has approved Vizamyl (flutemetamol F 18 injection), a radioactive diagnostic drug for use with positron emission tomography (PET) imaging of the brain in adults being evaluated for Alzheimer's disease (AD) and dementia.Dementia is associated with diminishing brain functions such as memory, judgment, language and complex motor skills.
Researchers demonstrate preventive effect of sterols in Alzheimer's disease
Source: Cholesterol News From Medical News Today [2013.10.28]
"Plant sterols are present in various combinations in nuts, seeds and plant oils. As plant sterols are the equivalents of animal cholesterol, they can in principal influence metabolic processes, where cholesterol is involved," explained Marcus Grimm, Head of the Experimental Neurology Laboratory at Saarland University.
Drugs for hypertension shown to decrease risk of Alzheimer's disease dementia
Source: Hypertension News From Medical News Today [2013.10.18]
A Johns Hopkins-led analysis of data previously gathered on more than 3,000 elderly Americans strongly suggests that taking certain blood pressure medications to control blood pressure may reduce the risk of dementia due to Alzheimer's disease (AD).
Diabetes Doesn't Seem to Affect Alzheimer's Disease Progression
Source: MedicineNet Insulin Resistance Specialty [2013.07.30]
Title: Diabetes Doesn't Seem to Affect Alzheimer's Disease Progression
Category: Health News
Created: 7/29/2013 4:36:00 PM
Last Editorial Review: 7/30/2013 12:00:00 AM
Study first to use 'structural' approach in hunt for amyloid-inhibiting agents to treat Alzheimer's disease
Source: Muscular Dystrophy / ALS News From Medical News Today [2013.07.29]
UCLA chemists and molecular biologists have for the first time used a "structure-based" approach to drug design to identify compounds with the potential to delay or treat Alzheimer's disease, and possibly Parkinson's, Lou Gehrig's disease and other degenerative disorders.
Studying The Cell's Folding Machines May Help Prevent Alzheimer's Disease
Source: Huntingtons Disease News From Medical News Today [2013.07.02]
Scientists using sophisticated imaging techniques have observed a molecular protein folding process that may help medical researchers understand and treat diseases such as Alzheimer's, Lou Gehrig's and cancer.The study, reported in the journal Cell, verifies a process that scientists knew existed but with a mechanism they had never been able to observe, according to Dr.
Molecular System Identified That Could Help Develop Treatments For Alzheimer's Disease
Source: CJD / vCJD / Mad Cow Disease News From Medical News Today [2013.02.25]
Scientists from the University of Southampton have identified the molecular system that contributes to the harmful inflammatory reaction in the brain during neurodegenerative diseases.An important aspect of chronic neurodegenerative diseases, such as Alzheimer's, Parkinson's, Huntington's or prion disease, is the generation of an innate inflammatory reaction within the brain.
Alzheimer's Disease - Test Your Medical IQ
Source: MedicineNet donepezil Specialty [2012.02.07]
Title: Alzheimer's Disease - Test Your Medical IQ
Category: MedicineNet Quiz
Created: 2/2/2012 5:35:00 PM
Last Editorial Review: 2/7/2012 2:00:43 PM
Alzheimer's Disease Patient Caregiver Guide
Source: MedicineNet galantamine Specialty [2010.07.27]
Title: Alzheimer's Disease Patient Caregiver Guide
Category: Diseases and Conditions
Created: 8/26/2008 12:00:00 AM
Last Editorial Review: 7/27/2010 12:00:00 AM
ARICEPT (Donepezil) effective for severe Alzheimer's disease
Source: The Doctors Lounge - Neurology
Donepezil reverses some aspects of cognitive deterioration seen in severe Alzheimer's disease.
Global Burden of Dementia Underestimated: Report
Source: Medscape NeurologyHeadlines [2013.12.06]
On the eve of the G8 Dementia Summit, new estimates from Alzheimer's Disease International show a 'staggering' increase of 17% on figures published in 2009.
Medscape Medical News
Alzheimer's-related changes in the brains of those with risk gene may begin showing effects in childhood
Source: Genetics News From Medical News Today [2013.12.05]
People who carry a high-risk gene for Alzheimer's disease show changes in their brains beginning in childhood, decades before the illness appears, new research from the Centre for Addiction and Mental Health (CAMH) suggests.The gene, called SORL1, is one of a number of genes linked to an increased risk of late-onset Alzheimer's disease, the most common form of the illness.
Global dementia set to treble by 2050, says G8 briefing
Source: Public Health News From Medical News Today [2013.12.05]
A new analysis suggests that the number of people worldwide living with dementia is set to treble by 2050. Alzheimer's Disease International, a federation of Alzheimer associations, reveals their findings in a policy briefing on the global impact of dementia ahead of the first G8 Dementia Summit set to take place in the UK on December 11th.
Problems in clock genes contribute to neurodegeneration
Source: Sleep / Sleep Disorders / Insomnia News From Medical News Today [2013.11.28]
A new discovery may help explain the surprisingly strong connections between sleep problems and neurodegenerative conditions such as Alzheimer's disease. Sleep loss increases the risk of Alzheimer's disease, and disrupted sleeping patterns are among the first signs of this devastating disorder.Scientists at Washington University School of Medicine in St.
Tentative molecular link between head injury and Alzheimer's
Source: Sports Medicine / Fitness News From Medical News Today [2013.11.28]
Using a powerful laser imaging technique, a study led by the University of Cambridge in the UK shows how tiny pieces of a protein linked with Alzheimer's Disease could be the start of a process that leads to the onset and spread of the disease. The researchers also cautiously suggest the finding offers a plausible explanation as to why head injuries are linked to Alzheimer's.
Alzheimer's Gene Effects Show Up in Infancy (CME/CE)
Source: MedPage Today Neurology [2013.11.25]
(MedPage Today) -- Infants and toddlers with the Alzheimer's disease-associated APOE4 genotype already showed distinctive patterns of brain structure relative to other young children, researchers said.
Resveratrol mitigates effects of methamphetamine abuse
Source: Alcohol / Addiction / Illegal Drugs News From Medical News Today [2013.11.22]
Studies have shown that resveratrol, a natural compound found in colored vegetables, fruits and especially grapes, may minimize the impact of Parkinson's disease, stroke and Alzheimer's disease in those who maintain healthy diets or who regularly take resveratrol supplements.
APOE2 May Be Therapeutic in Alzheimer's (CME/CE)
Source: MedPage Today Psychiatry [2013.11.21]
(MedPage Today) -- Bathing the mouse brain in the APOE2 form of apolipoprotein E reduced levels of abnormal beta-amyloid protein compared with controls, suggesting that the protein could prevent Alzheimer's disease, researchers said.
Statin 'combats cognitive decline after surgery'
Source: Statins News From Medical News Today [2013.10.21]
A commonly prescribed statin has been found to reduce inflammation in the brains of mice following surgery - a process that can lead to post-operative cognitive dysfuntion and Alzheimer's disease. This is according to a study published in the journal Annals of Surgery.Researchers from Imperial College London in the UK, led by Dr.
How oxidative stress and mitochondrial damage relate to neurodegenerative diseases
Source: Muscular Dystrophy / ALS News From Medical News Today [2013.08.11]
Oxidative stress and mitochondrial damage have been implicated in the pathogenesis of several neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis.