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Mytelase (Ambenonium Chloride) - Description and Clinical Pharmacology

 
 



MYTELASE® (ambenonium chloride)

DESCRIPTION

MYTELASE, brand of ambenonium chloride, is [Oxalylbis (iminoethylene)] bis[(o -chlorobenzyl) diethylammonium] dichloride, a white crystalline powder, soluble in water to 20 percent (w/v).

Inactive Ingredients: Acacia, Dibasic Calcium Phosphate, Gelatin, Lactose, Magnesium Stearate, Starch, Sucrose.

CLINICAL PHARMACOLOGY

The compound is a cholinesterase inhibitor with all the pharmacologic actions of acetylcholine, both the muscarinic and nicotinic types. Cholinesterase inactivates acetylcholine. Like neostigmine, MYTELASE suppresses cholinesterase but has the advantage of longer duration of action and fewer side effects on the gastrointestinal tract. The longer duration of action also results in more even strength, better endurance, and greater residual effect during the night and on awakening than is produced by shorter-acting anticholinesterase compounds.

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