ADVERSE REACTIONS
The adverse reactions caused by morphine are essentially those observed with other opioid analgesics. They include the following major hazards: respiratory depression, apnea, and to a lesser degree, circulatory depression, respiratory arrest, shock and cardiac arrest.
Most Frequently Observed
Constipation, lightheadedness, dizziness, sedation, nausea, vomiting, sweating, dysphoria and euphoria.
Some of these effects seem to be more prominent in ambulatory patients and in those not experiencing severe pain. Some adverse reactions in ambulatory patients may be alleviated if the patient lies down.
Less Frequently Observed Reactions
Central Nervous System
Weakness, headache, agitation, tremor, uncoordinated muscle movements, seizure, alterations of mood (nervousness, apprehension, depression, floating feelings), dreams, muscle rigidity, transient hallucinations and disorientation, visual disturbances, insomnia and increased intracranial pressure
Gastrointestinal
Dry mouth, biliary tract spasm, laryngospasm, anorexia, diarrhea, cramps, taste alterations, constipation, ileus, intestinal obstruction, and increases in hepatic enzymes
Cardiovascular
Flushing of the face, chills, tachycardia, bradycardia, palpitation, faintness, syncope, hypotension and hypertension
Genitourinary
Urine retention or hesitance, reduced libido and/or potency
Dermatologic
Pruritus, urticaria, other skin rashes, edema and diaphoresis
Other
Antidiuretic effect, paresthesia, muscle tremor, blurred vision, nystagmus, diplopia, miosis and anaphylaxis
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REPORTS OF SIDE EFFECTS / ADVERSE REACTIONS RELATED TO MORPHINE
Below is a sample of reports where side effects / adverse reactions may be related to Morphine. The information is not vetted and should not be cosidered as verified clinical evidence.
Possible Morphine side effects / adverse reactions in 50 year old male
Reported by a consumer/non-health professional from United States on 2007-01-05
Patient: 50 year old male weighing 111.1 kg (244.5 pounds)
Reactions: Urinary Incontinence, Somnolence, Loss of Consciousness, Cardio-Respiratory Arrest, Medication Error, Device Malfunction, Cold Sweat, Anuria, Cough, Muscle Spasms, Dyspnoea, Incorrect Dose Administered, Faecal Incontinence, Respiratory Arrest, Disturbance in Attention, Memory Impairment
Adverse event resulted in: life threatening event
Suspect drug(s):
Morphine
Possible Morphine side effects / adverse reactions in 40 year old female
Reported by a individual with unspecified qualification from United States on 2007-01-05
Patient: 40 year old female weighing 133.8 kg (294.4 pounds)
Reactions: Respiratory Rate Decreased, Post Procedural Complication, Oxygen Saturation Decreased, Loss of Consciousness
Suspect drug(s):
Morphine
Other drugs received by patient: Venlafaxine HCL; Cefazolin; Apap TAB; Lansoprazole
Possible Morphine side effects / adverse reactions in 62 year old male
Reported by a individual with unspecified qualification from Norway on 2007-01-12
Patient: 62 year old male
Reactions: Vomiting, Abdominal Pain Upper, Gastritis, Gastroduodenitis
Adverse event resulted in: hospitalization
Suspect drug(s):
Albyl-E
Dosage: 75 mg/day
Administration route: Oral
Indication: Nephrolithiasis
Start date: 2006-12-19
Confortid
Dosage: 100 mg/day
Indication: Nephrolithiasis
Start date: 2006-12-19
Morphine
Indication: Nephrolithiasis
Start date: 2006-12-19
Voltaren
Dosage: 100 mg/day
Indication: Nephrolithiasis
Start date: 2006-12-19
End date: 2006-12-19
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