Media Articles Related to Monurol (Fosfomycin)
Urinary Tract Infection in Adults Quiz
Source: MedicineNet Hydronephrosis Specialty [2014.02.28]
Title: Urinary Tract Infection in Adults Quiz
Category: MedicineNet Quiz
Created: 6/10/2010 12:17:00 PM
Last Editorial Review: 2/28/2014 1:19:24 PM
Important mechanism which plays a role in urinary tract infections decoded
Source: Urology / Nephrology News From Medical News Today [2014.02.07]
Bacterial urinary tract infections are a painful nuisance. A team of researchers led by scientists from the University of Bonn Medical Center has now decoded the way in which immune cells communicate with each other in defense against infections via the messenger tumor necrosis factor (TNF). The results are now being published in the renowned journal Cell.
New research: Cranberry concentrate reduces risk of urinary tract infections in elderly
Source: Complementary Medicine / Alternative Medicine News From Medical News Today [2014.01.22]
New research  published in the American Journal of Geriatrics shows that over 25% of bladder infections (cystitis) can be reduced with the regular use of cranberry concentrate supplements in vulnerable older people in nursing homes at high risk of urinary tract infections. Over 20% of these high-risk elderly did not develop any UTI's at all when taking the cranberry capsule.
Urinary Tract Infections in Children
Source: MedicineNet Bedwetting Specialty [2013.12.20]
Title: Urinary Tract Infections in Children
Category: Diseases and Conditions
Created: 2/1/2010 5:57:00 PM
Last Editorial Review: 12/20/2013 12:00:00 AM
Urinary Tract Infection (UTI) Pictures Slideshow: Bladder Infection Symptoms, Causes and Treatments
Source: MedicineNet Interstitial Cystitis Specialty [2013.07.29]
Title: Urinary Tract Infection (UTI) Pictures Slideshow: Bladder Infection Symptoms, Causes and Treatments
Created: 2/18/2011 1:26:00 PM
Last Editorial Review: 7/29/2013 12:00:00 AM
Published Studies Related to Monurol (Fosfomycin)
A randomized comparative study of single-dose fosfomycin and 5-day ciprofloxacin in female patients with uncomplicated lower urinary tract infections. [2010.12]
Uncomplicated lower urinary tract infections (UTIs) are the most frequent infections in females... It was concluded that the use of FMT as a first-line treatment in the empirical treatment of uncomplicated UTIs might have a positive impact on the problem of resistance to other antibiotics.
Fosfomycin versus other antibiotics for the treatment of cystitis: a
meta-analysis of randomized controlled trials. 
other antibiotics for the treatment of patients with cystitis... CONCLUSIONS: In the era of high drug resistance rates, reported even among
Fosfomycin in a single dose versus a 7-day course of amoxicillin-clavulanate for the treatment of asymptomatic bacteriuria during pregnancy. [2009.12]
The purpose of this paper was to compare the efficacy of a single dose of 3 g of fosfomycin to that of a 7-day regimen of amoxicillin-clavulanate in the treatment of asymptomatic bacteriuria during pregnancy. A randomised, prospective, interventional, analytical, longitudinal study was undertaken, in which the efficacy of two antibiotic regimens (one short and the other long) in the treatment of pregnant women with asymptomatic bacteriuria is compared...
Intravenous and intramuscular pharmacokinetics of a single-daily dose of disodium-fosfomycin in cattle, administered for 3 days. [2007.02]
Pharmacokinetic parameters of fosfomycin in cattle were determined after administration of buffered disodium fosfomycin either intravenously (i.v.) or intramuscularly (i.m.) at a dose of 20 mg/kg/day for 3 days. Calculated concentrations at time zero and maximum serum concentrations were 34.42 and 10.18 mug/mL, respectively.
Prevention of recurrent lower urinary tract infections by long-term administration of fosfomycin trometamol. Double blind, randomized, parallel group, placebo controlled study. 
Three hundred and seventeen non pregnant females, suffering of recurrent lower urinary tract infections (UTIs; at least three episodes in the preceding 12 months) were enrolled in a double blind, randomized placebo (PL) controlled, parallel group clinical study, addressed to evaluate the efficacy and safety of fosfomycin trometamol (CAS 78964-85-9, FT, Monuril) in the prevention of infectious recurrences of lower urinary tract.
Clinical Trials Related to Monurol (Fosfomycin)
Colistin Versus Colistin Plus Fosfomycin for Infections Caused by MDR Acinetobacter Baumannii [Recruiting]
In Siriraj Hospital, colistin alone for treatment of MDR A. baumannii contributed to
mortality 45% Fosfomycin is an antimicrobial which has activity against gram-negative
bacterial including MDR A. baumannii In this study, we compare the clinical and
microbiologicalresponse of colistin alone versus colistin plus fosfomycin in treatment of A.
baumannii infected patients
Single Dose Monurol for Treatment of Acute Cystitis [Recruiting]
Urinary tract infecton (UTI) is a very common problem in young healthy women, afflicting
approximately one-half of women by their late 20's. One of the most common antibiotics used
to treat UTIs is Trimethoprim-sulfa (TMP-SMX), usually for total of three days. However,
concerns about increased antibiotic resistance have led to increased interest in studying
other antibiotics for UTI.
An alternative antibiotic which is also FDA approved for the treatment of UTIs is fosfomycin
(Monurol). The effectiveness of fosfomycin in curing UTIs when given as a single dose is not
well studied. The purpose of this research study is to determine what the cure rates are
with a single dose of fosfomycin versus the more standard 3-day course of TMP-SMX.
Fosfomycin Plus Imipenem for Treatment of Infective Endocarditis [Recruiting]
Immediate vs. Conditional Use of Antibiotics in Uncomplicated Urinary Tract Infection (UTI) - ICUTI [Recruiting]
In this study, patients with uncomplicated urinary infection are investigated. It is
investigated if treatment of only symptoms of the uncomplicated urinary infection is as
effective as treatment with antibiotics with respect to the outcome of the urinary
infection. If this is the case, the use of antibiotics in the treatment of uncomplicated
urinary infections might be reduced.
Secondary aim of the study is the safety evaluation of both treatment strategies with
respect to SAEs during treatment. Additionally, relapse frequency after 28 days is
Study Evaluating Fosfomycin/Tobramycin for Inhalation in Cystic Fibrosis Patients With Pseudomonas Aeruginosa Lung Infection [Recruiting]
The purpose of this study is to evaluate the safety and efficacy of 2 dose combinations of
fosfomycin/tobramycin for inhalation (FTI), following a 28-day course of Aztreonam for
Inhalation (AZLI) in patients with cystic fibrosis and Pseudomonas aeruginosa lung