DOSAGE AND ADMINISTRATION
Osteoarthritis and Rheumatoid Arthritis
Carefully consider the potential benefits and risks of Mobic® (meloxicam) tablets/oral suspension and other treatment options before deciding to use MOBIC tablets/oral suspension. Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals (see WARNINGS).
After observing the response to initial therapy with MOBIC tablets/oral suspension, the dose should be adjusted to suit an individual patient's needs.
For the relief of the signs and symptoms of osteoarthritis the recommended starting and maintenance oral dose of MOBIC is 7.5 mg once daily. Some patients may receive additional benefit by increasing the dose to 15 mg once daily. For the relief of the signs and symptoms of rheumatoid arthritis, the recommended starting and maintenance oral dose of MOBIC is 7.5 mg once daily. Some patients may receive additional benefit by increasing the dose to 15 mg once daily.
MOBIC oral suspension 7.5 mg/5 mL or 15 mg/10 mL may be substituted for MOBIC tablets 7.5 mg or 15 mg, respectively.
The maximum recommended daily oral dose of MOBIC is 15 mg regardless of formulation.
Pauciarticular and Polyarticular Course Juvenile Rheumatoid Arthritis (JRA)
MOBIC oral suspension is available in the strength of 7.5 mg/5 mL. To improve dosing accuracy in smaller weight children, the use of the MOBIC oral suspension is recommended. For the treatment of juvenile rheumatoid arthritis, the recommended oral dose of MOBIC is 0.125 mg/kg once daily up to a maximum of 7.5 mg. There was no additional benefit demonstrated by increasing the dose above 0.125 mg/kg once daily in these clinical trials.
Juvenile Rheumatoid Arthritis dosing using the oral suspension should be individualized based on the weight of the child:
|12 kg (26 lb)||1.0 mL||1.5 mg|
|24 kg (54 lb)||2.0 mL ||3.0 mg|
|36 kg (80 lb)||3.0 mL ||4.5 mg|
|48 kg (106 lb)||4.0 mL ||6.0 mg|
|≥60 kg (132 lb)||5.0 mL||7.5 mg|
Shake the oral suspension gently before using.
Mobic® (meloxicam) tablets/oral suspension may be taken without regard to timing of meals.