MIOSTAT SUMMARY
Miostat
carbachol intraocular
solution, USP 0.01%
MIOSTAT® (carbachol intraocular solution, USP) is a sterile balanced salt solution of carbachol for intraocular injection.
Miostat (carbachol OPHTHALMIC) is indicated for the following:
Intraocular use for obtaining miosis during surgery. In addition, MIOSTAT (carbachol intraocular solution, USP) reduces the intensity of intraocular pressure elevation in the first 24 hours after cataract surgery.
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NEWS HIGHLIGHTS
Published Studies Related to Miostat (Carbachol Ophthalmic)
[The protective effects of carbachol on visceral ischemia-induced lipid peroxidation injury in rats with sepsis.] [2009.09]
OBJECTIVE: To investigate the effect of carbachol (CAR) on visceral perfusion and lipid oxidation injury in rats with sepsis... CONCLUSION: The results indicate that CAR promotes visceral perfusion, inhibits lipid peroxidation production and alleviates visceral edema and dysfunction in rats with sepsis.
Carbachol induces headache, but not migraine-like attacks, in patients with migraine without aura. [2009.07.09]
Schytz HW, Wienecke T, Olesen J & Ashina M. Carbachol induces headache, but not migraine-like attacks, in patients with migraine without aura.
Effects on hamster vocalization and aggression of carbachol injections into the MPOA/AH. [2009.02.16]
Recent work has shown that microinjections of the cholinergic agonist carbachol into the preoptic area (MPOA) increase 20-30 kHz ultrasonic vocalization in rats...
The cholinomimetic agent carbachol induces headache in healthy subjects. [2009.02]
The parasympathetic nervous system is likely to be involved in migraine pathogenesis. We hypothesized that the cholinomimetic agonist carbachol would induce headache and vasodilation of cephalic and radial arteries...
Curcumin reverses attenuated carbachol-induced contraction of the colon in a rat model of colitis. [2009]
BACKGROUND: Curcumin ameliorates colitis whether it reverses colitis-induced reduction in colonic contractility remains to be investigated. OBJECTIVES: To investigate the effect of curcumin on colitis-induced reduction of carbachol-induced contraction in colon segments from rats treated with trinitrobenzenesulphonic acid... CONCLUSIONS: Based on these findings it is concluded that curcumin prevented the reduction in carbachol-induced contraction in trinitrobenzenesulphonic acid -treated rats by modulating NF-kB signaling pathway.
Clinical Trials Related to Miostat (Carbachol Ophthalmic)
Carbachols Headache-Inducing Effect and Changes in Cerebral Blood Flow in Migraine Patients [Recruiting]
The purpose of this study is to test if carbachol infusion induces headache in migraine
subjects as well as intra- and extra-cerebral vasodilatation.
Carbachol´s Headache Inducing Characteristics and Effects on the Cerebral Blood Flow [Completed]
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