|
USE IN PREGNANCY
When used in pregnancy during the second and third trimesters, drugs that act directly on the renin-angiotensin system can cause injury and even death to the developing fetus. When pregnancy is detected, MICARDIS tablets should be discontinued as soon as possible.
See WARNINGS: Fetal/Neonatal Morbidity and Mortality
|
| |
MICARDIS SUMMARY
MICARDIS® (telmisartan) is a nonpeptide angiotensin II receptor (type AT1) antagonist.
MICARDIS (telmisartan) is indicated for the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents.
|
NEWS HIGHLIGHTSMedia Articles Related to Micardis (Telmisartan)
Micardis Given Wider Approval
Source: MedicineNet Heart Attack and Atherosclerosis Prevention Specialty [2009.10.20]
Title: Micardis Given Wider Approval
Category: Health News
Created: 10/19/2009 4:10:00 PM
Last Editorial Review: 10/20/2009
New Consortium Paves The Way For Improved Treatment Of Hypertension And Associated Vascular Complications
Source: Hypertension News From Medical News Today [2009.11.18]
Top Institute Pharma (TI Pharma) has formed a consortium with Actelion Pharmaceuticals Ltd, Erasmus Medical Centre and Maastricht University to define new modalities for the treatment of hypertension (high blood pressure) and associated vascular complications such as heart and kidney failure, myocardial infarction and stroke.
Kids with CKD Often Have Masked Hypertension (CME/CE)
Source: MedPage Today Nephrology [2009.11.13]
Many children with chronic kidney disease may have undetected hypertension, placing them at risk for enlarged hearts and future cardiovascular disease, a cross-sectional study showed.
Key Player Identified In Cascade That Leads To Hypertension-Related Kidney Damage
Source: Hypertension News From Medical News Today [2009.11.06]
A key player in a cascade that likely begins with stress and leads to high blood pressure and kidney damage has been identified by researchers who say the finding may lead to better ways to control both. Medical College of Georgia researchers have found endothelin, a powerful blood vessel constrictor and inflammatory peptide, increases the number of T cells in the kidneys, which helps recruit other immune cells, causing inflammation and destruction.
A Recipe For Hypertension: High Fructose Corn Syrup
Source: Hypertension News From Medical News Today [2009.10.31]
A diet high in fructose increases the risk of developing high blood pressure (hypertension), according to a paper presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego, California. The findings suggest that cutting back on processed foods and beverages that contain high fructose corn syrup (HFCS) may help prevent hypertension.
Published Studies Related to Micardis (Telmisartan)
Telmisartan in migraine prophylaxis: a randomized, placebo-controlled trial. [2009.09]
We evaluated telmisartan 80 mg for migraine prophylaxis. Migraine patients (n = 95) with three to seven migraine attacks in 3 months were randomized, double-blind to telmisartan or placebo...
Effect of telmisartan on renal outcomes: a randomized trial. [2009.07.07]
BACKGROUND: Angiotensin-receptor blockers (ARBs) blunt progression of advanced diabetic nephropathy, but their long-term renal effects in other patients are not clear. OBJECTIVE: To examine the long-term renal effects of telmisartan versus placebo in adults at high vascular risk... CONCLUSION: In adults with vascular disease but without macroalbuminuria, the effects of telmisartan on major renal outcomes were similar to those of placebo.
Prognostic value of blood pressure in patients with high vascular risk in the Ongoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial study. [2009.07]
BACKGROUND: Hypertension guidelines advise aggressive blood pressure (BP) lowering in patients with diabetes or high cardiovascular risk, but supporting evidence is limited. We analysed the impact of BP on cardiovascular events in well treated high-risk patients enrolled in a large clinical trial (Ongoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial)... CONCLUSION: In high-risk patients, the benefits from SBP lowering below 130 mmHg are driven mostly by a reduction of stroke; myocardial infarction is unaffected and cardiovascular mortality is unchanged or increased. Future trials should be designed to test the value of SBP lowering in high-risk patients with SBP in the range of 130-150 mmHg.
Comparison of the effects of ramipril versus telmisartan on high-sensitivity C-reactive protein and endothelial progenitor cells after acute coronary syndrome. [2009.06.01]
To compare the anti-inflammatory and endothelial progenitor cell mobilizing effects of ramipril and telmisartan in patients presenting with acute coronary syndrome (ACS), 42 patients with ACS were randomized after successful percutaneous coronary intervention to ramipril 5 mg/day (22 patients) or telmisartan 80 mg/day (20 patients)...
Results of treatment with telmisartan-amlodipine in hypertensive patients. [2009.04]
This randomized 4 x 4 factorial study determined the efficacy and safety of telmisartan (T) plus amlodipine (A) in hypertensive patients. Adults (N=1461) with stage 1 or 2 hypertension (baseline blood pressure [BP]: 153.2[12.1]/101.7[4.3] mm Hg) were randomized to 1 of 16 treatment groups with T 0, 20, 40, 80 mg and A 0, 2.5, 5, 10 mg for 8 weeks...
Clinical Trials Related to Micardis (Telmisartan)
Telmisartan80mg/hydrochlothiazide12.5mg (Micardis Plus) ABPM Study in China [Completed]
to evaluate the trough and peak effect of once daily MICARDIS PLUS? (Telmisartan 80mg /
hydrochlorot hiazide 12. 5 mg) by 24 ABPM in patients with mild to moderate essential
hypertension
INNOVATION Study - Telmisartan (Micardis?) in Incipient Diabetic Nephropathy [Completed]
The aim of this study is to compare the preventive effect of Telmisartan (Micardis?) versus
placebo control on the transition to overt nephropathy in patients with diabetic nephropathy
manifesting mic roalbuminuria associated with type II diabetes, and to evaluate the efficacy
and safety of Telmisart an (Micardis?, Gliosartan?, Kinzal?, Kinzalmono?, Predxal?, Pritor?,
Samertan?, Telmisartan?) for di abetic nephropathy patients.
Telmisartan80/HCTZ25 Versus telmisartan80/HCTZ12.5 in Hypertension Not Responding to telmisartan80/HCTZ12.5 [Completed]
The primary objective of this trial is to demonstrate that a fixed dose combination of
telmisartan 8 0 mg plus hydrochlorothiazide 25 mg (T80/H25) is superior in reducing blood
pressure after eight wee ks compared with a fixed dose combination of telmisartan 80 mg plus
hydrochlorothiazide 12. 5 mg (T80
/H12. 5) in patients who fail to respond to six weeks treatment with T80/H12. 5.
Trial of Telmisartan 80mg/HCTZ 12.5mg and Telmisartan 40mg/HCTZ 12.5mg in Patients With Hypertension [Completed]
The objective of this trial is to assess the safety and efficacy of 52 weeks of open-label
treatment with the fixed dose combination of telmisartan 80 mg plus HCTZ 12. 5 mg and
telmisartan 40 mg plus H CTZ 12. 5 mg in patients with essential hypertension.
Non-Responder Study to Telmisartan 40mg [Completed]
The objective of this trial is to demonstrate that the fixed dose combination of telmisartan
40 mg a nd HCTZ 12. 5 mg is superior to the monocomponent of telmisartan (Micardis?,
Gliosartan?, Kinzal?, Ki nzalmono?, Predxal?, Pritor?, Samertan?, Telmisartan?) 40 mg in
patients with essential hypertension who fail to respond adequately to telmisartan
monotherapy.
|
PATIENT REVIEWS / RATINGS / COMMENTSBased on a total of 3 ratings/reviews, Micardis has an overall score of 5.67. The effectiveness score is 6.67 and the side effect score is 7.33. The scores are on ten point scale: 10 - best, 1 - worst.
| | Micardis review by 55 year old female patient | | | Rating |
| Overall rating: | |   |
| Effectiveness: | | Considerably Effective |
| Side effects: | | No Side Effects | | |
Treatment Info |
| Condition / reason: | | hypertension |
| Dosage & duration: | | 40 mg taken daily for the period of ongoing, for six months |
| Other conditions: | | diabetes type 2, depression/anxiety |
| Other drugs taken: | | metformin hydrochloride, venlafaxine hydrochloride | | |
Reported Results |
| Benefits: | | reduced blood pressure to within acceptable limits. replaced previous drug (ACE inhibitor) with undesirable side effects. |
| Side effects: | | none noticed |
| Comments: | | one tablet daily, in the morning. |
|
| | Micardis review by 56 year old female patient | | | Rating |
| Overall rating: | | |
| Effectiveness: | | Moderately Effective |
| Side effects: | | Moderate Side Effects | | |
Treatment Info |
| Condition / reason: | | High blood pressure |
| Dosage & duration: | | 80 mg taken daily for the period of 5 years |
| Other conditions: | | menopause |
| Other drugs taken: | | premarin progesterone | | |
Reported Results |
| Benefits: | | The drug Micardis did seem to alleviate my high blood pressure to some degree though definitely not entirely. My blood pressure is still higher than I or my doctor would like it to be. At the moment it averages about 140 over 90 but it was 180 over 110. Therefore I would say it was somewhat efficacious. It also alleviated some headaches that I assume were blood pressure related. |
| Side effects: | | I find when I am taking Micardis that I tend to be very tired and my libido is decreased. |
| Comments: | | I take Micardis in pill form once daily. |
|
| | Micardis review by 56 year old female patient | | | Rating |
| Overall rating: | | |
| Effectiveness: | | Moderately Effective |
| Side effects: | | Moderate Side Effects | | |
Treatment Info |
| Condition / reason: | | High blood pressure |
| Dosage & duration: | | 80 mg taken daily for the period of 5 years |
| Other conditions: | | menopause |
| Other drugs taken: | | premarin progesterone | | |
Reported Results |
| Benefits: | | The drug Micardis did seem to alleviate my high blood pressure to some degree though definitely not entirely. My blood pressure is still higher than I or my doctor would like it to be. At the moment it averages about 140 over 90 but it was 180 over 110. Therefore I would say it was somewhat efficacious. It also alleviated some headaches that I assume were blood pressure related. |
| Side effects: | | I find when I am taking Micardis that I tend to be very tired and my libido is decreased. |
| Comments: | | I take Micardis in pill form once daily. |
|
|
|
Page last updated: 2009-11-18
|
