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Mexitil (Mexiletine Hydrochloride) - Published Studies

 
 



Mexitil Related Published Studies

Well-designed clinical trials related to Mexitil (Mexiletine)

Mexiletine for symptoms and signs of myotonia in nondystrophic myotonia: a randomized controlled trial. [2012]

Mexiletine is an effective antimyotonia treatment in myotonic dystrophy type 1. [2010.05.04]

Morphine versus mexiletine for treatment of postamputation pain: a randomized, placebo-controlled, crossover trial. [2008.08]

Well-designed clinical trials possibly related to Mexitil (Mexiletine)

Evaluation of the traditional Chinese Medicine Shensongyangxin capsule on treating premature ventricular contractions: a randomized, double-blind, controlled multicenter trial. [2011.01]

Evaluation of the traditional Chinese Medicine Shensongyangxin capsule on treating premature ventricular contractions: a randomized, double-blind, controlled multicenter trial. [2011]

Skeletal muscle channelopathies: new insights into the periodic paralyses and nondystrophic myotonias. [2009.10]

Other research related to Mexitil (Mexiletine)

Translation of flecainide- and mexiletine-induced cardiac sodium channel inhibition and ventricular conduction slowing from nonclinical models to clinical. [2011.05]

Refractory erythromelalgia of the ears: response to mexiletine. [2011.03]

Combination therapy with mexiletine and sotalol suppresses inherited ventricular arrhythmias in German shepherd dogs better than mexiletine or sotalol monotherapy: a randomized cross-over study. [2010.08]

Mexiletine suppresses nodal persistent sodium currents in sensory axons of patients with neuropathic pain. [2010.05]

Intravenous lidocaine and mexiletine in the management of trigeminal autonomic cephalalgias. [2010.04]

Effects of mexiletine, a CYP1A2 inhibitor, on tizanidine pharmacokinetics and pharmacodynamics. [2010.03]

Comparison of the effect of mexiletine and methylprednisolone on neural function and histopathological damage after transient spinal cord ischemia in rabbits. [2010.01]

A case of mexiletine-induced hypersensitivity syndrome presenting as eosinophilic pneumonia. [2010.01]

Mexiletine is an effective antimyotonia treatment in myotonic dystrophy type 1. [2010]

Design and assessment of a potent sodium channel blocking derivative of mexiletine for minimizing experimental neuropathic pain in several rat models. [2009.10]

Effect of mexiletine on dynamic allodynia induced by chronic constriction injury of the sciatic nerve in rats. [2009.07]

Experience with oral mexiletine in primary erythromelalgia in children. [2009.07]

Mexiletine-responsive erythromelalgia due to a new Na(v)1.7 mutation showing use-dependent current fall-off. [2009.04]

Mexiletine for refractory chronic daily headache: a report of nine cases. [2008.11]

Mexiletine therapy for chronic pain: survival analysis identifies factors predicting clinical success. [2008.03]

[Determination of mexiletine in human blood by liquid chromatography-tandem mass spectrometry] [2007.12]

Gating properties of SCN5A mutations and the response to mexiletine in long-QT syndrome type 3 patients. [2007.09.04]

The effect of mexiletine on the level of lipid peroxidation and apoptosis of endothelium following experimental subarachnoid hemorrhage. [2006.12]

The effect of intravenously administered mexiletine on tinnitus - a pilot study. [2006.12]

Effect of congestive heart failure on mexiletine pharmacokinetics in a Japanese population. [2006.11]

Neuroprotective effect of mexiletine in the central nervous system of diabetic rats. [2006.06]

Effect of mexiletine on vincristine-induced painful neuropathy in mice. [2006.04.24]

Effects of mexiletine on electrical field stimulation-induced contractile responses in the ipsilateral and contralateral vasa deferentia after unilateral testicular torsion/detorsion. [2006]

Drug-induced hypersensitivity syndrome due to mexiletine hydrochloride associated with reactivation of human herpesvirus 7. [2006]

Prevention of ventricular extrasystole by mexiletine in patients with normal QT intervals is associated with a reduction of transmural dispersion of repolarization. [2005.08.03]

Drug-induced hypersensitivity syndrome due to mexiletine associated with human herpes virus 6 and cytomegalovirus reactivation. [2005.04]

Primary erythromelalgia in a child responding to intravenous lidocaine and oral mexiletine treatment. [2005.04]

The effects of mexiletine on excitability properties of human median motor axons. [2005.02]

Other possibly related research studies

Adjuvant analgesics. [2007.01]

Myotonia congenita--a cause of muscle weakness and stiffness. [2006.07]

Successful parental use of an automated external defibrillator for an infant with long-QT syndrome. [2006.08]

Evaluation of patients with paramyotonia at 23Na MR imaging during cold-induced weakness. [2006.08]

[An uncommon cause of recurrent abdominal pain in a 63-year-old obese woman] [2006.03.03]

Paced electrogram fractionation analysis of arrhythmogenic tendency in DeltaKPQ Scn5a mice. [2005.12]

Systemic administration of local anesthetics to relieve neuropathic pain: a systematic review and meta-analysis. [2005.12]

Drug therapy in Brugada syndrome. [2005.10]

Varicella zoster virus induces neuropathic changes in rat dorsal root ganglia and behavioral reflex sensitisation that is attenuated by gabapentin or sodium channel blocking drugs. [2005.11]

Relationship between sodium channel NaV1.3 expression and neuropathic pain behavior in rats. [2005.09]

Novel cyclopentane dicarboxamide sodium channel blockers as a potential treatment for chronic pain. [2005.04.01]

[A girl with hereditary myotonia due to an exceptional sodium channel mutation] [2006.11.11]

Anti-convulsants and anti-depressants. [2007]

The role of late I and antiarrhythmic drugs in EAD formation and termination in Purkinje fibers. [2006.05]

The effect of dehydroepiandrosterone sulfate (DHEAS) on myotonia: intracellular studies. [2005.12]

Sodium channel blockers in neuropathic pain. [2005]

Acute pain management pharmacology for the patient with concurrent renal or hepatic disease. [2005.06]

Specific therapy based on the genotype and cellular mechanism in inherited cardiac arrhythmias. Long QT syndrome and Brugada syndrome. [2005]

Critical review of oral drug treatments for diabetic neuropathic pain-clinical outcomes based on efficacy and safety data from placebo-controlled and direct comparative studies. [2005.05]

The effect of glutamate receptor blockers on glutamate release following spinal cord injury. Lack of evidence for an ongoing feedback cascade of damage --> glutamate release --> damage --> glutamate release --> etc. [2005.03.15]

Appropriate dosing of antiarrhythmic drugs in Japan requires therapeutic drug monitoring. [2005.02]

The cutaneous analgesic effect of class I antiarrhythmic drugs. [2007.04]

Intravenous lidocaine for neuropathic pain: diagnostic utility and therapeutic efficacy. [2007.02]

Optical mapping of ventricular arrhythmias in LQTS mice with SCN5A mutation N1325S. [2007.01.26]

Pharmacogenetics and anti-arrhythmic drug therapy: a theoretical investigation. [2007.01]

Comparative neuroprotective effect of sodium channel blockers after experimental spinal cord injury. [2007.07]

Burning mouth syndrome: will better understanding yield better management? [2007.06]

Ventricular ectopy during REM sleep: implications for nocturnal sudden cardiac death. [2007.05]

Do sodium channel blockers have neuroprotective effect after onset of ischemic insult? [2007.04]

[Current status and prospects of medical therapy for dystonia] [2006.11]

Ionic basis of pharmacological therapy in Brugada syndrome. [2007.02]

Effects of cardioactive medications on retrograde conduction: continuing relevance for current devices. [2006.01]

Pharmacologic management of neuropathic pain: Evidence-based recommendations. [2007.10.05]

[Gabapentin mitigates neuropathic pain in cancer patients--a case report] [2007.08]

Pharmacologic management of neuropathic pain: evidence-based recommendations. [2007.12.05]

Differential contribution of sodium channel subtypes to action potential generation in unmyelinated human C-type nerve fibers. [2007.09]

Treatment of painful neuropathy. [2007.10]

[Eulenburg's paramyotonia congenita] [2007.11]

Pharmacological management of neuropathic pain following spinal cord injury. [2008]

Pharmacological evaluation of morphine and non-opioid analgesic adjuvants in a mouse model of skin cancer pain. [2008.03]

The cardiac persistent sodium current: an appealing therapeutic target? [2008.03]

Effect of drugs on defibrillation capacity. [2008]

The evolution of pain management in the critically ill trauma patient: Emerging concepts from the global war on terrorism. [2008.07]

Multiple episodes of ventricular tachycardia induced by silent coronary vasospasm. [2008.04]

[Evaluation of efficacy and safety of adjuvant analgesics for peripheral neuropathy induced by cancer chemotherapy in digestive cancer patients-a pilot study] [2009.01]

[Central and peripheral mechanisms in antinociception: current and future perspectives] [2008.06]

Experimental studies of potential analgesics for the treatment of chemotherapy-evoked painful peripheral neuropathies. [2008.07]

Treatment of neuropathic pain: an overview of recent guidelines. [2009.10]

Effects of antiarrhythmic drugs on the hyperpolarization-activated cyclic nucleotide-gated channel current. [2009.06]

Central poststroke pain: a review of pathophysiology and treatment. [2009.05]

Involvement of voltage-gated sodium channels blockade in the analgesic effects of orphenadrine. [2009.04]

Characteristics of recurrent ventricular fibrillation associated with inferolateral early repolarization role of drug therapy. [2009.02.17]

Intravenous lidocaine infusion for the treatment of post-acoustic neuroma resection headache: a case report. [2009.02]

Pharmacological characterization and gene expression profiling of an L5/L6 spinal nerve ligation model for neuropathic pain in mice. [2008.05.02]

Pharmacologic management of chronic pain. [2010.06]

Trafficking defects and gating abnormalities of a novel SCN5A mutation question gene-specific therapy in long QT syndrome type 3. [2010.04.30]

Clinical characteristics and genetic background of congenital long-QT syndrome diagnosed in fetal, neonatal, and infantile life: a nationwide questionnaire survey in Japan. [2010.02.01]

Polymyositis presenting with cardiac manifestations: Report of two cases and review of the literature. [2010.02]

A case of myotonic dystrophy presenting with ventricular tachycardia and atrial fibrillation. [2009.07]

Malignant perinatal variant of long-QT syndrome caused by a profoundly dysfunctional cardiac sodium channel. [2008.12]

Neonatal long QT syndrome type 3 predicted by positive lidocaine challenge. [2010.03]

[Post-surgical neuropathic pain] [2009.07]

An interactive voice response diary for patients with non-dystrophic myotonia. [2011.07]

Class I/B antiarrhythmic property of ranolazine, a novel antianginal agent, in dog and human cardiac preparations. [2011.07.15]

The Electro-Mechanical window: a risk marker for Torsade de Pointes in a canine model of drug induced arrhythmias. [2010.12]

Is epidural analgesia necessary after video-assisted thoracoscopic lobectomy? [2010.10]

Ventricular tachycardia in infants with structurally normal heart: a benign disorder. [2010.12]

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