Metrogel (Metronidazole Topical Gel) - Summary

METROGEL SUMMARY

MetroGel^® Topical Gel contains metronidazole, USP, at a concentration of 7.5 mg per gram (0.75%) in a gel consisting of purified water, methylparaben, propylparaben, propylene glycol, carbomer 940, sodium hydroxide, and edetate disodium. Metronidazole is classified therapeutically as an antiprotozoal and antibacterial agent.

MetroGel^® Topical Gel is indicated for topical application in the treatment of inflammatory papules and pustules of rosacea.

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METROGEL NEWS HIGHLIGHTS

Published Studies Related to Metrogel (Metronidazole Topical)

Therapy of metronidazole with azathioprine to prevent postoperative recurrence of Crohn's disease: a controlled randomized trial. [2008.10]

Clinical and microbiological benefits of systemic metronidazole and amoxicillin in the treatment of smokers with chronic periodontitis: a randomized placebo-controlled study. [2008.10]

Intravaginally applied metronidazole is as effective as orally applied in the treatment of bacterial vaginosis, but exhibits significantly less side effects. [2008.09.03]

Ciprofloxacin or metronidazole for the treatment of perianal fistulas in patients with Crohn's disease: A randomized, double-blind, placebo-controlled pilot study. [2008.07.30]

Topical metronidazole can reduce pain after surgery and pain on defecation in postoperative hemorrhoidectomy. [2008.02]

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Clinical Trials Related to Metrogel (Metronidazole Topical)

An Evaluation of the Cosmetic Appearance of Metronidazole Gel (MetroGel®) 1% [Completed]

Efficacy of Metronidazole Versus Metronidazole and Rifampin in CDAD Treatment [Completed]

Sequential Vaccinations in Prostate Cancer Patients [Active, not recruiting]

Assess the Ability of MetroGel 1% to Deliver Moisture to Facial Skin After a Single Application [Completed]

A Study to Evaluate the Safety and Effectiveness of Ertapenem Versus Ceftriaxone/Metronidazole in the Treatment of Intra-Abdominal Infections in Adults [Completed]

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METROGEL PATIENT REVIEWS / RATINGS / COMMENTS

Metrogel review by 36 year old female patient
		Rating
Overall rating:
Effectiveness:		Ineffective
Side effects:		Moderate Side Effects
		Treatment Info
Condition / reason:		rosacea
Dosage & duration:		topical (dosage frequency: twice per day) for the period of a few weeks
Other conditions:		none
Other drugs taken:		none
		Reported Results
Benefits:		There were not any benefits. Galderma changed metrogel and the new formula didn't agree with my skin.
Side effects:		my skin became very red and irritated.
Comments:		i used the new metrogel. the old formula is no longer available. The new one doesn't work for me.

Metrogel review by 56 year old male patient
		Rating
Overall rating:
Effectiveness:		Considerably Effective
Side effects:		No Side Effects
		Treatment Info
Condition / reason:		roseasa
Dosage & duration:		1 x per day (dosage frequency: 1 x per day) for the period of 4 years and counting
Other conditions:		Psoriatic Arthritis
Other drugs taken:		Enbrel [biologic drug]
		Reported Results
Benefits:		--reduced redness on face [especially around nose and cheek areas] --helps reduce time that an open sore heals on face. --overall - I am satisfied with Metrogel's performance concering Roseasa.
Side effects:		I have not found any side affects as of yet.
Comments:		Thin layer of Metrogel over affected areas of face 1x per day after face has been washed and is dry.

Metrogel review by 60 year old female patient
		Rating
Overall rating:
Effectiveness:		Ineffective
Side effects:		Extremely Severe Side Effects
		Treatment Info
Condition / reason:		redness from rosacea flushing
Dosage & duration:		1% (dosage frequency: applied it twice a day) for the period of just a few days because of bad reaction
Other conditions:		fibromyalgia, cervical disc disease, depression
Other drugs taken:		Effexor XR, Hydrocodone, Klonopin
		Reported Results
Benefits:		None. This product as all prescription and nonprecriptions products that are available in the USA have offered no relief whatsoever from the flushing of Rosacea and extremely sensitive skin.
Side effects:		This product immeidately caused my skin to turn bright red. It stung and I had to wash it off. I tried it a couple more days and then gave up, just as I have on all Rosacea medications. Very very frustrating.
Comments:		My dermatologist doctor has yet to find something to help me. I have also had laser treatments that are suppose to calm the skin but to no avail. There is a new medication out that is like doxycycline but is suppose to help the redness of Rosacea. I can't remember the name of it. But I tried that also and was on it for two months. With no improvement, the doctor stopped me taking it.